"Caffeine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.
| Descriptor ID |
D002110
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| MeSH Number(s) |
D03.132.960.175 D03.633.100.759.758.824.175
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Caffeine".
Below are MeSH descriptors whose meaning is more specific than "Caffeine".
This graph shows the total number of publications written about "Caffeine" by people in this website by year, and whether "Caffeine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Caffeine" by people in Profiles.
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Association of Maternal Caffeine Consumption During Pregnancy With Child Growth. JAMA Netw Open. 2022 10 03; 5(10):e2239609.
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Association between self-reported caffeine intake during pregnancy and social responsiveness scores in childhood: The EARLI and HOME studies. PLoS One. 2021; 16(1):e0245079.
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Dietary behaviors and poor sleep quality among young adult women: watch that sugary caffeine! Sleep Health. 2020 04; 6(2):214-219.
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Maternal caffeine intake during pregnancy and risk of obesity in offspring: a prospective cohort study. Int J Obes (Lond). 2015 Apr; 39(4):658-64.
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Coffee, ADORA2A, and CYP1A2: the caffeine connection in Parkinson's disease. Eur J Neurol. 2011 May; 18(5):756-65.
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Maternal caffeine consumption during pregnancy and the risk of miscarriage: a prospective cohort study. Am J Obstet Gynecol. 2008 Mar; 198(3):279.e1-8.
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Association of fractures with caffeine and alcohol in postmenopausal women: the Iowa Women's Health Study. Public Health Nutr. 2000 Sep; 3(3):253-61.
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Intake of fluids and methylxanthine-containing beverages: association with colon cancer. Int J Cancer. 1999 Apr 12; 81(2):199-204.
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Differences in fertility associated with caffeinated beverage consumption. Am J Public Health. 1998 Feb; 88(2):270-4.
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Caffeine intake in relation to the risk of primary cardiac arrest. Epidemiology. 1997 Sep; 8(5):505-8.