"Theophylline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.
| Descriptor ID |
D013806
|
| MeSH Number(s) |
D03.132.960.751 D03.633.100.759.758.824.751
|
| Concept/Terms |
Theophylline- Theophylline
- 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
- 1,3-Dimethylxanthine
- 1,3 Dimethylxanthine
|
Below are MeSH descriptors whose meaning is more general than "Theophylline".
Below are MeSH descriptors whose meaning is more specific than "Theophylline".
This graph shows the total number of publications written about "Theophylline" by people in this website by year, and whether "Theophylline" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Theophylline" by people in Profiles.
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Asthma exacerbation rates in adults are unchanged over a 5-year period despite high-intensity therapy. J Allergy Clin Immunol Pract. 2014 Sep-Oct; 2(5):570-4.e1.
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Shared treatment decision making improves adherence and outcomes in poorly controlled asthma. Am J Respir Crit Care Med. 2010 Mar 15; 181(6):566-77.
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The effect of active and passive household cigarette smoke exposure on pregnant women with asthma. Chest. 2010 Mar; 137(3):601-8.
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Clinical practice. Asthma in pregnancy. N Engl J Med. 2009 Apr 30; 360(18):1862-9.
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Randomized trial of inhaled beclomethasone dipropionate versus theophylline for moderate asthma during pregnancy. Am J Obstet Gynecol. 2004 Mar; 190(3):737-44.
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The efficacy and safety of asthma medications during pregnancy. Semin Perinatol. 2001 Jun; 25(3):145-52.
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ATP modification of serotonin-induced contraction of the rat pulmonary artery. Proc Soc Exp Biol Med. 1997 Mar; 214(3):233-41.
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Adenosine modulates reactive hyperemia in rat gut. J Physiol Pharmacol. 1993 Jun; 44(2):119-37.
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Cardiac arrhythmias during the combined use of beta-adrenergic agonist drugs and theophylline. Chest. 1986 Jul; 90(1):45-51.