"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
| Descriptor ID |
D007328
|
| MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
|
| Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
|
Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 2 | 1 | 3 |
| 1996 | 2 | 0 | 2 |
| 1997 | 1 | 1 | 2 |
| 1998 | 1 | 1 | 2 |
| 1999 | 2 | 3 | 5 |
| 2000 | 1 | 0 | 1 |
| 2001 | 3 | 1 | 4 |
| 2002 | 2 | 2 | 4 |
| 2003 | 4 | 1 | 5 |
| 2004 | 1 | 4 | 5 |
| 2005 | 1 | 5 | 6 |
| 2006 | 6 | 10 | 16 |
| 2007 | 4 | 7 | 11 |
| 2008 | 4 | 1 | 5 |
| 2009 | 4 | 5 | 9 |
| 2010 | 3 | 7 | 10 |
| 2011 | 0 | 5 | 5 |
| 2012 | 4 | 4 | 8 |
| 2013 | 7 | 5 | 12 |
| 2014 | 2 | 3 | 5 |
| 2015 | 2 | 6 | 8 |
| 2016 | 4 | 3 | 7 |
| 2017 | 4 | 2 | 6 |
| 2018 | 0 | 2 | 2 |
| 2019 | 2 | 1 | 3 |
| 2020 | 1 | 2 | 3 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 4 | 4 |
| 2023 | 0 | 2 | 2 |
| 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Insulin" by people in Profiles.
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Cardiovascular and mortality benefits of sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide 1 receptor agonists as third-step glucose-lowering medicine in patients with type 2 diabetes: a retrospective cohort analysis. BMJ Open Diabetes Res Care. 2024 May 06; 12(3).
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Newer Pharmacologic Treatments in Adults With Type 2 Diabetes: A Clinical Guideline From the American College of Physicians. Ann Intern Med. 2024 May; 177(5):658-666.
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Metformin Cessation and Dementia Incidence. JAMA Netw Open. 2023 10 02; 6(10):e2339723.
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Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake. Nat Genet. 2023 06; 55(6):973-983.
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Development and validation of prediction models for gestational diabetes treatment modality using supervised machine learning: a population-based cohort study. BMC Med. 2022 09 15; 20(1):307.
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Weight loss and ß-cell responses following gastric banding or pharmacotherapy in adults with impaired glucose tolerance or type 2 diabetes: a randomized trial. Obesity (Silver Spring). 2022 08; 30(8):1579-1588.
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Evaluation of Outcomes Following Hospital-Wide Implementation of a Subcutaneous Insulin Protocol for Diabetic Ketoacidosis. JAMA Netw Open. 2022 04 01; 5(4):e226417.
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Association of Glyburide and Subcutaneous Insulin With Perinatal Complications Among Women With Gestational Diabetes. JAMA Netw Open. 2022 Mar 01; 5(3):e225026.
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Incentivizing Prescription Drug Switching to Reduce Patient and Health Plan Spending: A Microsimulation Model. Value Health. 2022 03; 25(3):427-434.
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Association of Real-time Continuous Glucose Monitoring With Glycemic Control and Acute Metabolic Events Among Patients With Insulin-Treated Diabetes. JAMA. 2021 06 08; 325(22):2273-2284.