TCF Transcription Factors
"TCF Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of DNA-binding proteins that are primarily expressed in T-LYMPHOCYTES. They interact with BETA CATENIN and serve as transcriptional activators and repressors in a variety of developmental processes.
| Descriptor ID |
D051820
|
| MeSH Number(s) |
D12.776.260.730 D12.776.660.235.400.800 D12.776.664.235.400.800 D12.776.930.875
|
| Concept/Terms |
TCF Transcription Factors- TCF Transcription Factors
- Transcription Factors, TCF
- Lymphoid Enhancer Factors
- T-Cell Factors
- T Cell Factors
- LEF Transcription Factors
- Transcription Factors, LEF
|
Below are MeSH descriptors whose meaning is more general than "TCF Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "TCF Transcription Factors".
This graph shows the total number of publications written about "TCF Transcription Factors" by people in this website by year, and whether "TCF Transcription Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 3 | 0 | 3 |
| 2007 | 3 | 0 | 3 |
| 2008 | 2 | 1 | 3 |
| 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "TCF Transcription Factors" by people in Profiles.
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Genetic architecture of type 2 diabetes: recent progress and clinical implications. Diabetes Care. 2009 Jun; 32(6):1107-14.
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Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways. Mutat Res. 2009 Jan 15; 660(1-2):12-21.
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Transcription factor 7-like 2 polymorphism and colon cancer. Cancer Epidemiol Biomarkers Prev. 2008 Apr; 17(4):978-82.
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Effects of TCF7L2 polymorphisms on obesity in European populations. Obesity (Silver Spring). 2008 Feb; 16(2):476-82.
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TCF7L2 rs7903146 variant does not associate with smallness for gestational age in the French population. BMC Med Genet. 2007 Jun 25; 8:37.
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TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis. J Mol Med (Berl). 2007 Jul; 85(7):777-82.
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Transcription factor 7-like 2 (TCF7L2) is associated with gestational diabetes mellitus and interacts with adiposity to alter insulin secretion in Mexican Americans. Diabetes. 2007 May; 56(5):1481-5.
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No major contribution of TCF7L2 sequence variants to maturity onset of diabetes of the young (MODY) or neonatal diabetes mellitus in French white subjects. Diabetologia. 2007 Jan; 50(1):214-6.
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TCF7L2 variation predicts hyperglycemia incidence in a French general population: the data from an epidemiological study on the Insulin Resistance Syndrome (DESIR) study. Diabetes. 2006 Nov; 55(11):3189-92.
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Transcription factor TCF7L2 genetic study in the French population: expression in human beta-cells and adipose tissue and strong association with type 2 diabetes. Diabetes. 2006 Oct; 55(10):2903-8.