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Anny Hui Xiang, PhD, MS

TitleSenior Investigator
InstitutionKaiser Permanente Southern California
DepartmentDepartment of Research and Evaluation
ORCID ORCID Icon0000-0003-2786-1268 Additional info
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    Other Positions
    TitleDirector, Division of Biostatistics Research
    InstitutionKaiser Permanente Southern California
    DepartmentDepartment of Research and Evaluation


    Collapse Overview 
    Collapse overview
    Dr. Anny Xiang is an investigator and applied biostatistician who uses statistical methodologies to understand disease development and to conduct clinical trials in disease prevention and intervention. Her focus has been on diabetes, gestational diabetes, obesity, women’s health, racial and ethnic disparities as well as impact of diabetic exposure on offspring. Additional research interests include methodological investigation of biostatistical questions arising from clinical studies; design and conduct of clinical trials to assess treatment and intervention efficacy/safety and effectiveness; collaborative investigations of etiology, biology, and risk factors for disease development. Dr. Xiang is an adjunct research associate professor at the University of Southern California’s Keck School of Medicine.

    Collapse Research 
    Collapse research activities and funding
    R01DK061628     (BUCHANAN, THOMAS A)Apr 1, 2002 - Apr 30, 2014
    NIH/NIDDK
    Genetics of Beta Cell Failure in Mexican Americans
    Role: Co-Principal Investigator

    R21DK066243     (XIANG, ANNY H)Jan 1, 2004 - Dec 31, 2006
    NIH/NIDDK
    Contraceptive in Women with Prior Gestational Diabetes
    Role: Principal Investigator

    R18DK062319     (XIANG, ANNY H)Sep 1, 2004 - Sep 30, 2009
    NIH/NIDDK
    Prevention and Control of Diabetes in Families
    Role: Principal Investigator

    R01DK100302     (XIANG, ANNY H)Jul 21, 2014 - Jun 30, 2017
    NIH/NIDDK
    The Role of Adipokines in Glucose Regulation and Metabolic Decline
    Role: Principal Investigator

    R56ES028121     (XIANG, ANNY H)Sep 15, 2017 - Sep 14, 2018
    NIH/NIEHS
    Effects of air pollution and gestational diabetes on autism
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Koebnick C, Black MH, Wu J, Shu YH, MacKay AW, Watanabe RM, Buchanan TA, Xiang AH. A diet high in sugar-sweetened beverage and low in fruits and vegetables is associated with adiposity and a pro-inflammatory adipokine profile. Br J Nutr. 2018 Dec; 120(11):1230-1239. PMID: 30375290.
      View in: PubMed
    2. Xiang AH, Wang X, Martinez MP, Getahun D, Page KA, Buchanan TA, Feldman K. Maternal Gestational Diabetes Mellitus, Type 1 Diabetes, and Type 2 Diabetes During Pregnancy and Risk of ADHD in Offspring. Diabetes Care. 2018 Dec; 41(12):2502-2508. PMID: 30373735.
      View in: PubMed
    3. Xiang AH, Trigo E, Martinez M, Katkhouda N, Beale E, Wang X, Wu J, Chow T, Montgomery C, Nayak KS, Hendee F, Buchanan TA. Impact of Gastric Banding Versus Metformin on ß-Cell Function in Adults With Impaired Glucose Tolerance or Mild Type 2 Diabetes. Diabetes Care. 2018 Dec; 41(12):2544-2551. PMID: 30282699.
      View in: PubMed
    4. Xiang AH, Black MH, Shu YH, Wu J, MacKay A, Koebnick C, Watanabe RM, Buchanan TA. Association of weight gain and fifteen adipokines with declining beta-cell function in Mexican Americans. PLoS One. 2018; 13(8):e0201568. PMID: 30102726.
      View in: PubMed
    5. Luo S, Alves J, Hardy K, Wang X, Monterosso J, Xiang AH, Page KA. Neural processing of food cues in pre-pubertal children. Pediatr Obes. 2018 Jul 17. PMID: 30019454.
      View in: PubMed
    6. Nguyen HQ, Moy ML, Fan VS, Gould MK, Xiang A, Bailey A, Desai S, Coleman KJ. Applying the pragmatic-explanatory continuum indicator summary to the implementation of a physical activity coaching trial in chronic obstructive pulmonary disease. Nurs Outlook. 2018 Sep; 66(5):455-463. PMID: 30144938.
      View in: PubMed
    7. Xiang AH, Wang X, Martinez MP, Page K, Buchanan TA, Feldman RK. Maternal Type 1 Diabetes and Risk of Autism in Offspring. JAMA. 2018 07 03; 320(1):89-91. PMID: 29936530.
      View in: PubMed
    8. Langer-Gould A, Lucas R, Xiang AH, Chen LH, Wu J, Gonzalez E, Haraszti S, Smith JB, Quach H, Barcellos LF. MS Sunshine Study: Sun Exposure But Not Vitamin D Is Associated with Multiple Sclerosis Risk in Blacks and Hispanics. Nutrients. 2018 Feb 27; 10(3). PMID: 29495467.
      View in: PubMed
    9. Black MH, Shu YH, Wu J, Koebnick C, MacKay A, Watanabe RM, Buchanan TA, Xiang AH. Longitudinal Increases in Adiposity Contribute to Worsening Adipokine Profile over Time in Mexican Americans. Obesity (Silver Spring). 2018 04; 26(4):703-712. PMID: 29427376.
      View in: PubMed
    10. Langer-Gould A, Lucas RM, Xiang AH, Wu J, Chen LH, Gonzales E, Haraszti S, Smith JB, Quach H, Barcellos LF. Vitamin D-Binding Protein Polymorphisms, 25-Hydroxyvitamin D, Sunshine and Multiple Sclerosis. Nutrients. 2018 Feb 07; 10(2). PMID: 29414925.
      View in: PubMed
    11. Getahun D, Jacobsen SJ, Fassett MJ, Wing DA, Xiang AH, Chiu VY, Peltier MR. Association between maternal hypothyroidism and autism spectrum disorders in children. Pediatr Res. 2018 Mar; 83(3):580-588. PMID: 29244797.
      View in: PubMed
    12. Manosroi W, Tan JW, Rariy CM, Sun B, Goodarzi MO, Saxena AR, Williams JS, Pojoga LH, Lasky-Su J, Cui J, Guo X, Taylor KD, Chen YI, Xiang AH, Hsueh WA, Raffel LJ, Buchanan TA, Rotter JI, Williams GH, Seely EW. The Association of Estrogen Receptor-ß Gene Variation With Salt-Sensitive Blood Pressure. J Clin Endocrinol Metab. 2017 11 01; 102(11):4124-4135. PMID: 28938457.
      View in: PubMed
    13. Langer-Gould A, Wu J, Lucas R, Smith J, Gonzales E, Amezcua L, Haraszti S, Chen LH, Quach H, James JA, Barcellos LF, Xiang AH. Epstein-Barr virus, cytomegalovirus, and multiple sclerosis susceptibility: A multiethnic study. Neurology. 2017 Sep 26; 89(13):1330-1337. PMID: 28855411.
      View in: PubMed
    14. Langer-Gould A, Smith JB, Hellwig K, Gonzales E, Haraszti S, Koebnick C, Xiang A. Breastfeeding, ovulatory years, and risk of multiple sclerosis. Neurology. 2017 Aug 08; 89(6):563-569. PMID: 28701499.
      View in: PubMed
    15. Wood AR, Jonsson A, Jackson AU, Wang N, van Leewen N, Palmer ND, Kobes S, Deelen J, Boquete-Vilarino L, Paananen J, Stancáková A, Boomsma DI, de Geus EJC, Eekhoff EMW, Fritsche A, Kramer M, Nijpels G, Simonis-Bik A, van Haeften TW, Mahajan A, Boehnke M, Bergman RN, Tuomilehto J, Collins FS, Mohlke KL, Banasik K, Groves CJ, McCarthy MI, Pearson ER, Natali A, Mari A, Buchanan TA, Taylor KD, Xiang AH, Gjesing AP, Grarup N, Eiberg H, Pedersen O, Chen YD, Laakso M, Norris JM, Smith U, Wagenknecht LE, Baier L, Bowden DW, Hansen T, Walker M, Watanabe RM, 't Hart LM, Hanson RL, Frayling TM. A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants. Diabetes. 2017 08; 66(8):2296-2309. PMID: 28490609.
      View in: PubMed
    16. Xiang AH. Association of Maternal Diabetes With Autism in Offspring. JAMA. 2017 02 07; 317(5):537-538. PMID: 28170476.
      View in: PubMed
    17. Getahun D, Fassett MJ, Peltier MR, Wing DA, Xiang AH, Chiu V, Jacobsen SJ. Association of Perinatal Risk Factors with Autism Spectrum Disorder. Am J Perinatol. 2017 Feb; 34(3):295-304. PMID: 28099978.
      View in: PubMed
    18. Coleman KJ, Caparosa SL, Nichols JF, Fujioka K, Koebnick C, McCloskey KN, Xiang AH, Ngor EW, Levy SS. Understanding the Capacity for Exercise in Post-Bariatric Patients. Obes Surg. 2017 01; 27(1):51-58. PMID: 27229736.
      View in: PubMed
    19. Huang BZ, Chang JI, Li E, Xiang AH, Wu BU. Influence of Statins and Cholesterol on Mortality Among Patients With Pancreatic Cancer. J Natl Cancer Inst. 2017 05; 109(5). PMID: 28040693.
      View in: PubMed
    20. Palmer ND, Wagenknecht LE, Langefeld CD, Wang N, Buchanan TA, Xiang AH, Allayee H, Bergman RN, Raffel LJ, Chen YD, Haritunians T, Fingerlin T, Goodarzi MO, Taylor KD, Rotter JI, Watanabe RM, Bowden DW. Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium. Diabetes. 2016 07; 65(7):2072-80. PMID: 27207554; PMCID: PMC4915581 [Available on 07/01/17].
    21. Inzhakova G, Zhou H, Morris M, Early MI, Xiang AH, Jacobsen SJ, Derose SF. Potential of risk-based population guidelines to reduce cardiovascular risk in a large integrated health system. Am J Manag Care. 2016 05 01; 22(5):e161-8. PMID: 27266582.
      View in: PubMed
    22. Bider-Canfield Z, Martinez MP, Wang X, Yu W, Bautista MP, Brookey J, Page KA, Buchanan TA, Xiang AH. Maternal obesity, gestational diabetes, breastfeeding and childhood overweight at age 2 years. Pediatr Obes. 2017 04; 12(2):171-178. PMID: 26956226.
      View in: PubMed
    23. Chen Z, Salam MT, Toledo-Corral C, Watanabe RM, Xiang AH, Buchanan TA, Habre R, Bastain TM, Lurmann F, Wilson JP, Trigo E, Gilliland FD. Ambient Air Pollutants Have Adverse Effects on Insulin and Glucose Homeostasis in Mexican Americans. Diabetes Care. 2016 04; 39(4):547-54. PMID: 26868440; PMCID: PMC4806768 [Available on 04/01/17].
    24. Gao C, Wang N, Guo X, Ziegler JT, Taylor KD, Xiang AH, Hai Y, Kridel SJ, Nadler JL, Kandeel F, Raffel LJ, Chen YD, Norris JM, Rotter JI, Watanabe RM, Wagenknecht LE, Bowden DW, Speliotes EK, Goodarzi MO, Langefeld CD, Palmer ND. A Comprehensive Analysis of Common and Rare Variants to Identify Adiposity Loci in Hispanic Americans: The IRAS Family Study (IRASFS). PLoS One. 2015; 10(11):e0134649. PMID: 26599207; PMCID: PMC4658008.
    25. Nguyen HQ, Bailey A, Coleman KJ, Desai S, Fan VS, Gould MK, Maddock L, Miller K, Towner W, Xiang AH, Moy ML. Patient-centered physical activity coaching in COPD (Walk On!): A study protocol for a pragmatic randomized controlled trial. Contemp Clin Trials. 2016 Jan; 46:18-29. PMID: 26597414.
      View in: PubMed
    26. Baudrand R, Goodarzi MO, Vaidya A, Underwood PC, Williams JS, Jeunemaitre X, Hopkins PN, Brown N, Raby BA, Lasky-Su J, Adler GK, Cui J, Guo X, Taylor KD, Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH, Pojoga LH. A prevalent caveolin-1 gene variant is associated with the metabolic syndrome in Caucasians and Hispanics. Metabolism. 2015 Dec; 64(12):1674-81. PMID: 26475177; PMCID: PMC4641791 [Available on 12/01/16].
    27. Xiang AH. Maternal Diabetes and Autism in Offspring--Reply. JAMA. 2015 Jul 28; 314(4):407. PMID: 26219063.
      View in: PubMed
    28. Xiang AH, Wang X, Martinez MP, Walthall JC, Curry ES, Page K, Buchanan TA, Coleman KJ, Getahun D. Association of maternal diabetes with autism in offspring. JAMA. 2015 Apr 14; 313(14):1425-34. PMID: 25871668.
      View in: PubMed
    29. Chen Z, Salam MT, Karim R, Toledo-Corral CM, Watanabe RM, Xiang AH, Buchanan TA, Habre R, Bastain TM, Lurmann F, Taher M, Wilson JP, Trigo E, Gilliland FD. Living near a freeway is associated with lower bone mineral density among Mexican Americans. Osteoporos Int. 2015 Jun; 26(6):1713-21. PMID: 25677718; PMCID: PMC4470808.
    30. Black MH, Wu J, Takayanagi M, Wang N, Taylor KD, Haritunians T, Trigo E, Lawrence JM, Watanabe RM, Buchanan TA, Xiang AH. Variation in PPARG is associated with longitudinal change in insulin resistance in Mexican Americans at risk for type 2 diabetes. J Clin Endocrinol Metab. 2015 Mar; 100(3):1187-95. PMID: 25584717; PMCID: PMC4333029.
    31. Palmer ND, Goodarzi MO, Langefeld CD, Wang N, Guo X, Taylor KD, Fingerlin TE, Norris JM, Buchanan TA, Xiang AH, Haritunians T, Ziegler JT, Williams AH, Stefanovski D, Cui J, Mackay AW, Henkin LF, Bergman RN, Gao X, Gauderman J, Varma R, Hanis CL, Cox NJ, Highland HM, Below JE, Williams AL, Burtt NP, Aguilar-Salinas CA, Huerta-Chagoya A, Gonzalez-Villalpando C, Orozco L, Haiman CA, Tsai MY, Johnson WC, Yao J, Rasmussen-Torvik L, Pankow J, Snively B, Jackson RD, Liu S, Nadler JL, Kandeel F, Chen YD, Bowden DW, Rich SS, Raffel LJ, Rotter JI, Watanabe RM, Wagenknecht LE. Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium. Diabetes. 2015 May; 64(5):1853-66. PMID: 25524916; PMCID: PMC4407862.
    32. Chen Z, Watanabe RM, Stram DO, Buchanan TA, Xiang AH. High calorie intake is associated with worsening insulin resistance and ß-cell function in Hispanic women after gestational diabetes mellitus. Diabetes Care. 2014 Dec; 37(12):3294-300. PMID: 25404660; PMCID: PMC4237976.
    33. Ghai NR, Reynolds KD, Xiang AH, Massie K, Rosetti S, Blanco L, Martinez MP, Quinn VP. Recruitment results among families contacted for an obesity prevention intervention: the Obesity Prevention Tailored for Health Study. Trials. 2014 Nov 27; 15:463. PMID: 25428433; PMCID: PMC4256806.
    34. Xiang AH, Black MH, Li BH, Martinez MP, Sacks DA, Lawrence JM, Buchanan TA, Jacobsen SJ. Racial and ethnic disparities in extremes of fetal growth after gestational diabetes mellitus. Diabetologia. 2015 Feb; 58(2):272-81. PMID: 25341460.
      View in: PubMed
    35. Nguyen HQ, Chu L, Amy Liu IL, Lee JS, Suh D, Korotzer B, Yuen G, Desai S, Coleman KJ, Xiang AH, Gould MK. Associations between physical activity and 30-day readmission risk in chronic obstructive pulmonary disease. Ann Am Thorac Soc. 2014 Jun; 11(5):695-705. PMID: 24713094.
      View in: PubMed
    36. Ren J, Xiang AH, Trigo E, Takayanagi M, Beale E, Lawrence JM, Hartiala J, Richey JM, Allayee H, Buchanan TA, Watanabe RM. Genetic variation in MTNR1B is associated with gestational diabetes mellitus and contributes only to the absolute level of beta cell compensation in Mexican Americans. Diabetologia. 2014 Jul; 57(7):1391-9. PMID: 24728128; PMCID: PMC4117246.
    37. Goodarzi MO, Langefeld CD, Xiang AH, Chen YD, Guo X, Hanley AJ, Raffel LJ, Kandeel F, Nadler JL, Buchanan TA, Norris JM, Fingerlin TE, Lorenzo C, Rewers MJ, Haffner SM, Bowden DW, Rich SS, Bergman RN, Rotter JI, Watanabe RM, Wagenknecht LE. Insulin sensitivity and insulin clearance are heritable and have strong genetic correlation in Mexican Americans. Obesity (Silver Spring). 2014 Apr; 22(4):1157-64. PMID: 24124113; PMCID: PMC3968231.
    38. Coleman KJ, Huang YC, Koebnick C, Reynolds K, Xiang AH, Black MH, Alskaf S. Metabolic syndrome is less likely to resolve in Hispanics and non-Hispanic blacks after bariatric surgery. Ann Surg. 2014 Feb; 259(2):279-85. PMID: 24100336.
      View in: PubMed
    39. Page KA, Romero A, Buchanan TA, Xiang AH. Gestational diabetes mellitus, maternal obesity, and adiposity in offspring. J Pediatr. 2014 Apr; 164(4):807-10. PMID: 24388326; PMCID: PMC3962700.
    40. Xiang AH, Watanabe RM, Buchanan TA. HOMA and Matsuda indices of insulin sensitivity: poor correlation with minimal model-based estimates of insulin sensitivity in longitudinal settings. Diabetologia. 2014 Feb; 57(2):334-8. PMID: 24305964; PMCID: PMC4139101.
    41. Restoring Insulin Secretion (RISE): design of studies of ß-cell preservation in prediabetes and early type 2 diabetes across the life span. Diabetes Care. 2014; 37(3):780-8. PMID: 24194506; PMCID: PMC3931376.
    42. Xiang AH, Takayanagi M, Black MH, Trigo E, Lawrence JM, Watanabe RM, Buchanan TA. Longitudinal changes in insulin sensitivity and beta cell function between women with and without a history of gestational diabetes mellitus. Diabetologia. 2013 Dec; 56(12):2753-60. PMID: 24030069; PMCID: PMC4139094.
    43. Black MH, Sacks DA, Xiang AH, Lawrence JM. Response to Comment on: Black et al. The relative contribution of prepregnancy overweight and obesity, gestational weight gain, and IADPSG-defined gestational diabetes mellitus to fetal overgrowth. Diabetes Care 2013;36:56-62. Diabetes Care. 2013 Aug; 36(8):e128. PMID: 23881981; PMCID: PMC3714517.
    44. Goodarzi MO, Guo X, Cui J, Jones MR, Haritunians T, Xiang AH, Chen YD, Taylor KD, Buchanan TA, Hsueh WA, Raffel LJ, Rotter JI. Systematic evaluation of validated type 2 diabetes and glycaemic trait loci for association with insulin clearance. Diabetologia. 2013 Jun; 56(6):1282-90. PMID: 23494448; PMCID: PMC3651757.
    45. Porter KR, Hsu JW, Chien GW, Xiang AH, Jung H, Chao C, Jacobsen SJ. Racial and ethnic differences in time to treatment for patients with localized prostate cancer. Urology. 2013 Feb; 81(2):283-7. PMID: 23374784.
      View in: PubMed
    46. Black MH, Watanabe RM, Trigo E, Takayanagi M, Lawrence JM, Buchanan TA, Xiang AH. High-fat diet is associated with obesity-mediated insulin resistance and ß-cell dysfunction in Mexican Americans. J Nutr. 2013 Apr; 143(4):479-85. PMID: 23343677; PMCID: PMC3738243.
    47. Chen Z, Black MH, Watanabe RM, Trigo E, Takayanagi M, Lawrence JM, Buchanan TA, Xiang AH. Self-reported physical activity is associated with ß-cell function in Mexican American adults. Diabetes Care. 2013 Mar; 36(3):638-44. PMID: 23223346; PMCID: PMC3579363.
    48. Black MH, Sacks DA, Xiang AH, Lawrence JM. The relative contribution of prepregnancy overweight and obesity, gestational weight gain, and IADPSG-defined gestational diabetes mellitus to fetal overgrowth. Diabetes Care. 2013 Jan; 36(1):56-62. PMID: 22891256; PMCID: PMC3526206.
    49. Buchanan TA, Xiang AH, Page KA. Gestational diabetes mellitus: risks and management during and after pregnancy. Nat Rev Endocrinol. 2012 Nov; 8(11):639-49. PMID: 22751341; PMCID: PMC4404707.
    50. Guo X, Cui J, Jones MR, Haritunians T, Xiang AH, Chen YD, Taylor KD, Buchanan TA, Davis RC, Hsueh WA, Raffel LJ, Rotter JI, Goodarzi MO. Insulin clearance: confirmation as a highly heritable trait, and genome-wide linkage analysis. Diabetologia. 2012 Aug; 55(8):2183-92. PMID: 22584727; PMCID: PMC3391346.
    51. Williams JS, Chamarthi B, Goodarzi MO, Pojoga LH, Sun B, Garza AE, Raby BA, Adler GK, Hopkins PN, Brown NJ, Jeunemaitre X, Ferri C, Fang R, Leonor T, Cui J, Guo X, Taylor KD, Ida Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH, Shi Y. Lysine-specific demethylase 1: an epigenetic regulator of salt-sensitive hypertension. Am J Hypertens. 2012 Jul; 25(7):812-7. PMID: 22534796; PMCID: PMC3721725.
    52. Xiang AH, Li BH, Black MH, Sacks DA, Buchanan TA, Jacobsen SJ, Lawrence JM. Racial and ethnic disparities in diabetes risk after gestational diabetes mellitus. Diabetologia. 2011 Dec; 54(12):3016-21. PMID: 22016046.
      View in: PubMed
    53. Segall-Gutierrez P, Xiang AH, Watanabe RM, Trigo E, Stanczyk FZ, Liu X, Jurow R, Buchanan TA. Deterioration in cardiometabolic risk markers in obese women during depot medroxyprogesterone acetate use. Contraception. 2012 Jan; 85(1):36-41. PMID: 22067800.
      View in: PubMed
    54. Pojoga LH, Underwood PC, Goodarzi MO, Williams JS, Adler GK, Jeunemaitre X, Hopkins PN, Raby BA, Lasky-Su J, Sun B, Cui J, Guo X, Taylor KD, Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH. Variants of the caveolin-1 gene: a translational investigation linking insulin resistance and hypertension. J Clin Endocrinol Metab. 2011 Aug; 96(8):E1288-92. PMID: 21613355; PMCID: PMC3146791.
    55. Bergman RN, Stefanovski D, Buchanan TA, Sumner AE, Reynolds JC, Sebring NG, Xiang AH, Watanabe RM. A better index of body adiposity. Obesity (Silver Spring). 2011 May; 19(5):1083-9. PMID: 21372804.
      View in: PubMed
    56. Buchanan TA, Watanabe RM, Xiang AH. Limitations in surrogate measures of insulin resistance. J Clin Endocrinol Metab. 2010 Nov; 95(11):4874-6. PMID: 21051585; PMCID: PMC2968734.
    57. Black MH, Sacks DA, Xiang AH, Lawrence JM. Clinical outcomes of pregnancies complicated by mild gestational diabetes mellitus differ by combinations of abnormal oral glucose tolerance test values. Diabetes Care. 2010 Dec; 33(12):2524-30. PMID: 20843973; PMCID: PMC2992182.
    58. Xiang AH, Kjos SL, Takayanagi M, Trigo E, Buchanan TA. Detailed physiological characterization of the development of type 2 diabetes in Hispanic women with prior gestational diabetes mellitus. Diabetes. 2010 Oct; 59(10):2625-30. PMID: 20682697; PMCID: PMC3279539.
    59. Buchanan TA, Xiang AH. Preventing type 2 diabetes with low-dose combinations. Lancet. 2010 Jul 10; 376(9735):72-4. PMID: 20605203.
      View in: PubMed
    60. Buchanan TA, Xiang AH. Diabetes: preventing type 2 diabetes mellitus: is metformin the answer? Nat Rev Endocrinol. 2010 May; 6(5):253-4. PMID: 20414319.
      View in: PubMed
    61. Xiang AH, Kawakubo M, Trigo E, Kjos SL, Buchanan TA. Declining beta-cell compensation for insulin resistance in Hispanic women with recent gestational diabetes mellitus: association with changes in weight, adiponectin, and C-reactive protein. Diabetes Care. 2010 Feb; 33(2):396-401. PMID: 19933993; PMCID: PMC2809290.
    62. Li X, Shu YH, Xiang AH, Trigo E, Kuusisto J, Hartiala J, Swift AJ, Kawakubo M, Stringham HM, Bonnycastle LL, Lawrence JM, Laakso M, Allayee H, Buchanan TA, Watanabe RM. Additive effects of genetic variation in GCK and G6PC2 on insulin secretion and fasting glucose. Diabetes. 2009 Dec; 58(12):2946-53. PMID: 19741163; PMCID: PMC2780888.
    63. Shu YH, Hartiala J, Xiang AH, Trigo E, Lawrence JM, Allayee H, Buchanan TA, Bottini N, Watanabe RM. Evidence for sex-specific associations between variation in acid phosphatase locus 1 (ACP1) and insulin sensitivity in Mexican-Americans. J Clin Endocrinol Metab. 2009 Oct; 94(10):4094-102. PMID: 19622628; PMCID: PMC2758733.
    64. Allison DC, Ahlmann ER, Xiang AH, Menendez LR. The linear cutting stapler may reduce surgical time and blood loss with muscle transection: a pilot study. Clin Orthop Relat Res. 2009 Nov; 467(11):2859-64. PMID: 19452238; PMCID: PMC2758975.
    65. Li X, Allayee H, Xiang AH, Trigo E, Hartiala J, Lawrence JM, Buchanan TA, Watanabe RM. Variation in IGF2BP2 interacts with adiposity to alter insulin sensitivity in Mexican Americans. Obesity (Silver Spring). 2009 Apr; 17(4):729-36. PMID: 19148120; PMCID: PMC4357482.
    66. Goodarzi MO, Taylor KD, Jones MR, Fang B, Guo X, Xiang AH, Buchanan TA, Hodis HN, Raffel LJ, Rotter JI. Replication of calpain-10 genetic association with carotid intima-media thickness. Atherosclerosis. 2009 Aug; 205(2):503-5. PMID: 19193380; PMCID: PMC2717175.
    67. Kopf D, Cheng LS, Blandau P, Hsueh W, Raffel LJ, Buchanan TA, Xiang AH, Davis RC, Rotter JI, Lehnert H. Association of insulin sensitivity and glucose tolerance with the c.825C>T variant of the G protein beta-3 subunit gene. J Diabetes Complications. 2008 May-Jun; 22(3):205-9. PMID: 18413224; PMCID: PMC2695761.
    68. Black MH, Fingerlin TE, Allayee H, Zhang W, Xiang AH, Trigo E, Hartiala J, Lehtinen AB, Haffner SM, Bergman RN, McEachin RC, Kjos SL, Lawrence JM, Buchanan TA, Watanabe RM. Evidence of interaction between PPARG2 and HNF4A contributing to variation in insulin sensitivity in Mexican Americans. Diabetes. 2008 Apr; 57(4):1048-56. PMID: 18162503; PMCID: PMC4447520.
    69. Xiang AH, Hodis HN, Kawakubo M, Peters RK, Kjos SL, Marroquin A, Goico J, Ochoa C, Liu CR, Liu CH, Buchanan TA. Effect of pioglitazone on progression of subclinical atherosclerosis in non-diabetic premenopausal Hispanic women with prior gestational diabetes. Atherosclerosis. 2008 Jul; 199(1):207-14. PMID: 18054942; PMCID: PMC2493568.
    70. Chen YC, Guo X, Raffel LJ, Xiang AH, Fang B, Hsueh WA, Taylor KD, Buchanan TA, Hodis HN, Rotter JI. Carotid intima-media thickness (cIMT) cosegregates with blood pressure and renal function in hypertensive Hispanic families. Atherosclerosis. 2008 May; 198(1):160-5. PMID: 18028933.
      View in: PubMed
    71. Buchanan TA, Xiang A, Kjos SL, Watanabe R. What is gestational diabetes? Diabetes Care. 2007 Jul; 30 Suppl 2:S105-11. PMID: 17596457.
      View in: PubMed
    72. Watanabe RM, Black MH, Xiang AH, Allayee H, Lawrence JM, Buchanan TA. Genetics of gestational diabetes mellitus and type 2 diabetes. Diabetes Care. 2007 Jul; 30 Suppl 2:S134-40. PMID: 17596461; PMCID: PMC2925642.
    73. Xiang AH, Kawakubo M, Buchanan TA, Kjos SL. A longitudinal study of lipids and blood pressure in relation to method of contraception in Latino women with prior gestational diabetes mellitus. Diabetes Care. 2007 Aug; 30(8):1952-8. PMID: 17519432.
      View in: PubMed
    74. Watanabe RM, Allayee H, Xiang AH, Trigo E, Hartiala J, Lawrence JM, Buchanan TA. Transcription factor 7-like 2 (TCF7L2) is associated with gestational diabetes mellitus and interacts with adiposity to alter insulin secretion in Mexican Americans. Diabetes. 2007 May; 56(5):1481-5. PMID: 17317761; PMCID: PMC2925638.
    75. Xiang AH, Wang C, Peters RK, Trigo E, Kjos SL, Buchanan TA. Coordinate changes in plasma glucose and pancreatic beta-cell function in Latino women at high risk for type 2 diabetes. Diabetes. 2006 Apr; 55(4):1074-9. PMID: 16567531.
      View in: PubMed
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    98. Langholz B, Thomas D, Xiang A, Stram D. Latency analysis in epidemiologic studies of occupational exposures: application to the Colorado Plateau uranium miners cohort. Am J Ind Med. 1999 Mar; 35(3):246-56. PMID: 9987557.
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    99. Kjos SL, Peters RK, Xiang A, Thomas D, Schaefer U, Buchanan TA. Contraception and the risk of type 2 diabetes mellitus in Latina women with prior gestational diabetes mellitus. JAMA. 1998 Aug 12; 280(6):533-8. PMID: 9707143.
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    102. Buchanan TA, Kjos SL, Schafer U, Peters RK, Xiang A, Byrne J, Berkowitz K, Montoro M. Utility of fetal measurements in the management of gestational diabetes mellitus. Diabetes Care. 1998 Aug; 21 Suppl 2:B99-106. PMID: 9704235.
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    103. Azen SP, Peters RK, Berkowitz K, Kjos S, Xiang A, Buchanan TA. TRIPOD (TRoglitazone In the Prevention Of Diabetes): a randomized, placebo-controlled trial of troglitazone in women with prior gestational diabetes mellitus. Control Clin Trials. 1998 Apr; 19(2):217-31. PMID: 9551285.
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    110. Xiang AH, Sather HN, Azen SP. Power considerations for testing an interaction in a 2 x k factorial design with a failure time outcome. Control Clin Trials. 1994 Dec; 15(6):489-502. PMID: 7851110.
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    111. Kjos SL, Ballagh SA, La Cour M, Xiang A, Mishell DR. The copper T380A intrauterine device in women with type II diabetes mellitus. Obstet Gynecol. 1994 Dec; 84(6):1006-9. PMID: 7970454.
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    113. Buchanan TA, Thawani H, Kades W, Modrall JG, Weaver FA, Laurel C, Poppiti R, Xiang A, Hsueh W. Angiotensin II increases glucose utilization during acute hyperinsulinemia via a hemodynamic mechanism. J Clin Invest. 1993 Aug; 92(2):720-6. PMID: 8349811; PMCID: PMC294906.
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