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Annette M. Langer-Gould, MD, PhD, MS

TitleAffiliated Investigator
InstitutionKaiser Permanente Southern California
DepartmentDepartment of Research and Evaluation
Address100 South Los Robles Avenue
Pasadena CA 91101
ORCID ORCID Icon0000-0001-6891-7147 Additional info
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    Collapse Overview 
    Collapse overview
    Annette Langer-Gould, MD, PhD, is a Research Scientist in the Department of Research & Evaluation. She serves as Regional Physician Multiple Sclerosis Champion at Kaiser Permanente Southern California, and is a practicing MS specialist at Los Angeles Medical Center. Her epidemiologic research focuses on the role of vitamin D, genotype, race/ethnicity, and MS susceptibility, as well as predictors of prognosis and comparative effectiveness of MS therapeutics. Dr. Langer-Gould also leads a team that is developing, implementing, and evaluating programs to provide high-quality affordable care for individuals with MS. She serves as the co-chair of the Choosing Wisely Committee, and is a member of the Guidelines Development, Dissemination, and Implementation Subcommittee for the American Academy of Neurology, and of the National MS Society's MS Prevalence Workgroup.

    Collapse Research 
    Collapse research activities and funding
    R01NS075308     (LANGER-GOULD, ANNETTE M)Jul 1, 2011 - Mar 31, 2017
    NIH
    Vitamin D, Race/Ethnicity, Genotype, and Multiple Sclerosis
    Role: Principal Investigator
    K23NS043207     (LANGER-GOULD, ANNETTE M)Aug 15, 2002 - Jul 31, 2008
    NIH
    Pregnancy and the Modulation of Multiple Sclerosis
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dunlop E, Daly A, Mori TA, Langer-Gould A, Pereira G, Black LJ. Plasma levels of polyunsaturated fatty acids and multiple sclerosis susceptibility in a US case-control study. Mult Scler Relat Disord. 2024 Oct 06; 92:105920. PMID: 39406153.
      Citations:    Fields:    
    2. Sideman AB, Nguyen HQ, Langer-Gould A, Lee EA, Borson S, Shen E, Tsoy E, Macias M, Goode C, Rankin K, Kramer J, Possin KL. Stakeholder-informed pragmatic trial protocol of the TabCAT-BHA for the detection of cognitive impairment in primary care. BMC Prim Care. 2024 Aug 06; 25(1):286. PMID: 39107706; PMCID: PMC11302096.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    3. Piehl F, Alping P, Virtanen S, Englund S, Burman J, Fink K, Fogdell-Hahn A, Gunnarsson M, Hillert J, Langer-Gould A, Lycke J, Mellerg?rd J, Nilsson P, Olsson T, Salzer J, Svenningsson A, Frisell T. COMBAT-MS: A Population-Based Observational Cohort Study Addressing the Benefit-Risk Balance of Multiple Sclerosis Therapies Compared with Rituximab. Ann Neurol. 2024 Jun 25. PMID: 38923558.
      Citations:    Fields:    Translation:Humans
    4. Alsalek S, Schwarzmann KB, Budhathoki S, Hernandez-Lopez V, Smith JB, Li BH, Langer-Gould A. Racial and Ethnic Disparities in the Incidence of Anti-NMDA Receptor Encephalitis. Neurol Neuroimmunol Neuroinflamm. 2024 Jul; 11(4):e200255. PMID: 38728608; PMCID: PMC11089538.
      Citations:    Fields:    Translation:Humans
    5. Akinsanya J, Smith JB, Langer-Gould A. Traumatic brain injury, race, ethnicity and cognition in newly diagnosed persons with multiple sclerosis. Mult Scler Relat Disord. 2024 Mar 25; 86:105577. PMID: 38579569.
      Citations:    Fields:    Translation:Humans
    6. Langer-Gould A, Li BH, Smith JB, Xu S. Multiple Sclerosis, Rituximab, Hypogammaglobulinemia, and Risk of Infections. Neurol Neuroimmunol Neuroinflamm. 2024 May; 11(3):e200211. PMID: 38507657; PMCID: PMC10959169.
      Citations: 3     Fields:    Translation:Humans
    7. Langer-Gould A, Igbinosa II. Disparities in Maternal and Infant Outcomes: What's a Neurologist to Do? Neurology. 2024 02 27; 102(4):e209207. PMID: 38261992.
      Citations:    Fields:    Translation:Humans
    8. Langer-Gould A, Sotirchos ES, Bourdette D. Rituximab for Multiple Sclerosis: Hiding in Plain Sight Neurology. 2024 01 23; 102(2):e208063. PMID: 38165314.
      Citations:    Fields:    Translation:Humans
    9. Langer-Gould AM, Smith JB, Gonzales EG, Piehl F, Li BH. Multiple Sclerosis, Disease-Modifying Therapies, and Infections. Neurol Neuroimmunol Neuroinflamm. 2023 Nov; 10(6). PMID: 37813594; PMCID: PMC10574822.
      Citations: 7     Fields:    Translation:Humans
    10. Longinetti E, Englund S, Burman J, Fink K, Fogdell-Hahn A, Gunnarsson M, Hillert J, Langer-Gould AM, Lycke J, Nilsson P, Salzer J, Svenningsson A, Mellerg?rd J, Olsson T, Piehl F, Frisell T. Trajectories of cognitive processing speed and physical disability over 11 years following initiation of a first multiple sclerosis disease-modulating therapy. J Neurol Neurosurg Psychiatry. 2023 Aug 09. PMID: 37558400.
      Citations: 1     Fields:    Translation:Humans
    11. Haben S, Ciplea AI, Tokic M, Timmesfeld N, Thiel S, Gold R, Langer-Gould AM, Hellwig K. Early postpartum treatment strategies and early postpartum relapses in women with active multiple sclerosis. J Neurol Neurosurg Psychiatry. 2023 Aug 03. PMID: 37536925.
      Citations: 3     Fields:    Translation:Humans
    12. Hittle M, Culpepper WJ, Langer-Gould A, Marrie RA, Cutter GR, Kaye WE, Wagner L, Topol B, LaRocca NG, Nelson LM, Wallin MT. Population-Based Estimates for the Prevalence of Multiple Sclerosis in the United States by Race, Ethnicity, Age, Sex, and Geographic Region. JAMA Neurol. 2023 07 01; 80(7):693-701. PMID: 37184850; PMCID: PMC10186207.
      Citations: 21     Fields:    Translation:Humans
    13. Hellwig K, Tokic M, Thiel S, Hemat S, Timmesfeld N, Ciplea AI, Gold R, Langer-Gould AM. Multiple Sclerosis Disease Activity and Disability Following Cessation of Fingolimod for Pregnancy. Neurol Neuroimmunol Neuroinflamm. 2023 07; 10(4). PMID: 37217309; PMCID: PMC10202774.
      Citations: 4     Fields:    Translation:Humans
    14. Myers LC, Kipnis P, Greene JD, Chen A, Creekmur B, Xu S, Sankar V, Roubinian NH, Langer-Gould A, Gould MK, Liu VX. The impact of timing of initiating invasive mechanical ventilation in COVID-19-related respiratory failure. J Crit Care. 2023 10; 77:154322. PMID: 37163851; PMCID: PMC10165890.
      Citations: 1     Fields:    Translation:Humans
    15. Fink K, Gorczyca A, Alping P, Englund S, Farmand S, Langer-Gould AM, Piehl F, McKay K, Frisell T, Razaz N. Multiple sclerosis, disease-modifying drugs and risk for adverse perinatal and pregnancy outcomes: Results from a population-based cohort study. Mult Scler. 2023 05; 29(6):731-740. PMID: 37073483; PMCID: PMC10176621.
      Citations: 2     Fields:    Translation:Humans
    16. Englund S, Kierkegaard M, Burman J, Fink K, Fogdell-Hahn A, Gunnarsson M, Hillert J, Langer-Gould A, Lycke J, Nilsson P, Salzer J, Svenningsson A, Mellerg?rd J, Olsson T, Longinetti E, Frisell T, Piehl F. Predictors of patient-reported fatigue symptom severity in a nationwide multiple sclerosis cohort. Mult Scler Relat Disord. 2022 Dec 23; 70:104481. PMID: 36603296.
      Citations: 4     Fields:    Translation:Humans
    17. Smith JB, Gonzales EG, Li BH, Langer-Gould A. Analysis of Rituximab Use, Time Between Rituximab and SARS-CoV-2 Vaccination, and COVID-19 Hospitalization or Death in Patients With Multiple Sclerosis. JAMA Netw Open. 2022 12 01; 5(12):e2248664. PMID: 36576740; PMCID: PMC9857265.
      Citations: 13     Fields:    Translation:HumansCellsPHPublic Health
    18. Myers LC, Xu S, Chen A, Greene JD, Creekmur B, Bruxvoort K, Escobar GJ, Adams JL, Langer-Gould A, Liu VX, Gould MK. The intensity of anticoagulant dosing in hospitalized patients with COVID-19: An observational, comparative effectiveness study. J Hosp Med. 2023 01; 18(1):43-54. PMID: 36345824; PMCID: PMC9877905.
      Citations: 1     Fields:    Translation:HumansCells
    19. Langer-Gould A, Xu S, Myers LC, Chen A, Greene JD, Creekmur B, Bruxvoort K, Adams JL, Liu V, Gould MK. Anakinra or high-dose corticosteroids in COVID-19 pneumonia patients who deteriorate on low-dose dexamethasone: an observational study of comparative effectiveness. Int J Infect Dis. 2023 Jan; 126:87-93. PMID: 36403818; PMCID: PMC9673073.
      Citations:    Fields:    Translation:HumansCells
    20. Langer-Gould A, Xu S, Myers LC, Chen A, Greene JD, Creekmur B, Bruxvoort K, Adams JL, Liu V, Gould MK. High-dose corticosteroids in patients hospitalized for COVID-19 pneumonia: an observational study of comparative effectiveness. Int J Infect Dis. 2022 Dec; 125:184-191. PMID: 36404464; PMCID: PMC9621697.
      Citations: 3     Fields:    Translation:HumansCells
    21. Spain RI, Piccio L, Langer-Gould AM. The Role of Diet in Multiple Sclerosis: Food for Thought. Neurology. 2023 Jan 24; 100(4):167-168. PMID: 36257715.
      Citations: 4     Fields:    Translation:Humans
    22. Longinetti E, Bower H, McKay KA, Englund S, Burman J, Fink K, Fogdell-Hahn A, Gunnarsson M, Hillert J, Langer-Gould A, Lycke J, Nilsson P, Salzer J, Svenningsson A, Mellerg?rd J, Olsson T, Piehl F, Frisell T. COVID-19 clinical outcomes and DMT of MS patients and population-based controls. Ann Clin Transl Neurol. 2022 09; 9(9):1449-1458. PMID: 35993445; PMCID: PMC9463950.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    23. Langer-Gould AM, Gonzales EG, Smith JB, Li BH, Nelson LM. Racial and Ethnic Disparities in Multiple Sclerosis Prevalence. Neurology. 2022 05 03; 98(18):e1818-e1827. PMID: 35501161; PMCID: PMC9109151.
      Citations: 31     Fields:    Translation:Humans
    24. Langer-Gould AM, Gonzales EG, Smith JB, Li BH, Nelson LM. Racial and Ethnic Disparities in Multiple Sclerosis Prevalence. Neurology. 2022 Apr 28. PMID: 35483901.
      Citations: 1     Fields:    
    25. Nguyen HQ, Borson S, Khang P, Langer-Gould A, Wang SE, Carrol J, Lee JS. Dementia diagnosis and utilization patterns in a racially diverse population within an integrated health care delivery system. Alzheimers Dement (N Y). 2022; 8(1):e12279. PMID: 35310534; PMCID: PMC8918121.
      Citations: 14     
    26. Langer-Gould A, Cheng SC, Li BH, Smith JB, Kanter MH, Kaiser Permanente Southern California Multiple Sclerosis specialist group. Decreasing Multiple Sclerosis Treatment Expenditures and Improving Quality at the Health System Level. Ann Neurol. 2022 Mar 13. PMID: 35285095.
      Citations: 4     Fields:    Translation:Humans
    27. Hellwig K, Tokic M, Thiel S, Esters N, Spicher C, Timmesfeld N, Ciplea AI, Gold R, Langer-Gould A. Multiple Sclerosis Disease Activity and Disability Following Discontinuation of Natalizumab for Pregnancy. JAMA Netw Open. 2022 Jan 04; 5(1):e2144750. PMID: 35072719.
      Citations: 23     Fields:    Translation:Humans
    28. Smith JB, Li BH, Gonzales EG, Langer-Gould A. Validation of algorithms for identifying outpatient infections in MS patients using electronic medical records. Mult Scler Relat Disord. 2021 Dec 05; 57:103449. PMID: 34915315.
      Citations: 4     Fields:    Translation:Humans
    29. McKay KA, Piehl F, Englund S, He A, Langer-Gould A, Hillert J, Frisell T. Rituximab Infusion Timing, Cumulative Dose, and Hospitalization for COVID-19 in Persons With Multiple Sclerosis in Sweden. JAMA Netw Open. 2021 12 01; 4(12):e2136697. PMID: 34851401; PMCID: PMC8637249.
      Citations: 5     Fields:    Translation:HumansCellsCTClinical Trials
    30. Amezcua L, Rivera VM, Vazquez TC, Baezconde-Garbanati L, Langer-Gould A. Health Disparities, Inequities, and Social Determinants of Health in Multiple Sclerosis and Related Disorders in the US: A Review. JAMA Neurol. 2021 12 01; 78(12):1515-1524. PMID: 34605866.
      Citations: 42     Fields:    Translation:Humans
    31. Lam K, Langer-Gould A. Open Access Fees: A Barrier to Scholarly Activity Among Neurology Trainees. Perm J. 2021 Nov 29; 25. PMID: 35348096; PMCID: PMC8784073.
      Citations: 1     Fields:    Translation:Humans
    32. Langer-Gould A, Cheng SC, Li BH, Kanter MH. The Multiple Sclerosis Treatment Optimization Program. Ann Clin Transl Neurol. 2021 11; 8(11):2146-2154. PMID: 34662494; PMCID: PMC8607446.
      Citations: 2     Fields:    Translation:Humans
    33. Langer-Gould A. Reader Response: Leadership, Recognition Awards, and Publication by Men and Women in the American Academy of Neurology. Neurology. 2021 07 27; 97(4):200-201. PMID: 34312311.
      Citations:    Fields:    Translation:Humans
    34. Langer-Gould A. Treating severe MS relapses during pregnancy. Mult Scler. 2021 09; 27(10):1623-1624. PMID: 33929268.
      Citations:    Fields:    Translation:Humans
    35. Langer-Gould A, Smith JB, Li BH, KPSC MS Specialist Group. Multiple sclerosis, rituximab, and COVID-19. Ann Clin Transl Neurol. 2021 04; 8(4):938-943. PMID: 33783140; PMCID: PMC8045943.
      Citations: 24     Fields:    Translation:Humans
    36. Langer-Gould A, Klocke S, Beaber B, Brara SM, Debacker J, Ayeni O, Nielsen AS. Improving quality, affordability, and equity of multiple sclerosis care. Ann Clin Transl Neurol. 2021 04; 8(4):980-991. PMID: 33751857; PMCID: PMC8045931.
      Citations: 5     Fields:    Translation:Humans
    37. McFaul D, Hakopian NN, Smith JB, Nielsen AS, Langer-Gould A. Defining Benign/Burnt-Out MS and Discontinuing Disease-Modifying Therapies. Neurol Neuroimmunol Neuroinflamm. 2021 03; 8(2). PMID: 33558306; PMCID: PMC8057062.
      Citations: 5     Fields:    Translation:Humans
    38. Black LJ, Hetherton S, Forkan M, Gonzales EG, Smith JB, Daly A, Lucas RM, Langer-Gould A. An exploratory study of diet in childhood and young adulthood and adult-onset multiple sclerosis. Mult Scler. 2021 09; 27(10):1611-1614. PMID: 33464166; PMCID: PMC8286980.
      Citations: 5     Fields:    Translation:Humans
    39. Razaz N, Piehl F, Frisell T, Langer-Gould AM, McKay KA, Fink K. Disease activity in pregnancy and postpartum in women with MS who suspended rituximab and natalizumab. Neurol Neuroimmunol Neuroinflamm. 2020 11; 7(6). PMID: 33087582; PMCID: PMC7641107.
      Citations: 10     Fields:    Translation:Humans
    40. Adams CJ, Wu SL, Shao X, Bradshaw PT, Gonzales E, Smith JB, Xiang AH, Bellesis KH, Chinn T, Bos SD, Wendel-Haga M, Olsson T, Kockum I, Langer-Gould AM, Schaefer C, Alfredsson L, Barcellos LF. Pregnancy does not modify the risk of MS in genetically susceptible women. Neurol Neuroimmunol Neuroinflamm. 2020 11; 7(6). PMID: 33037103; PMCID: PMC7673284.
      Citations: 1     Fields:    Translation:Humans
    41. Langer-Gould A. Editorial Response to Drs. Simone and Mancusi. Int J Infect Dis. 2020 12; 101:367. PMID: 33017695; PMCID: PMC7531338.
      Citations:    Fields:    Translation:HumansCells
    42. Langer-Gould A, Smith JB, Gonzales EG, Castillo RD, Figueroa JG, Ramanathan A, Li BH, Gould MK. Early identification of COVID-19 cytokine storm and treatment with anakinra or tocilizumab. Int J Infect Dis. 2020 Oct; 99:291-297. PMID: 32768693; PMCID: PMC7406519.
      Citations: 53     Fields:    Translation:HumansCellsPHPublic Health
    43. Ciplea AI, Langer-Gould A, Stahl A, Thiel S, Queisser-Wahrendorf A, Gold R, Hellwig K. Safety of potential breast milk exposure to IFN-ß or glatiramer acetate: One-year infant outcomes. Neurol Neuroimmunol Neuroinflamm. 2020 07; 7(4). PMID: 32434802; PMCID: PMC7251509.
      Citations: 13     Fields:    Translation:Humans
    44. Smith JB, Hellwig K, Fink K, Lyell DJ, Piehl F, Langer-Gould A. Rituximab, MS, and pregnancy. Neurol Neuroimmunol Neuroinflamm. 2020 07; 7(4). PMID: 32358226; PMCID: PMC7217660.
      Citations: 23     Fields:    Translation:Humans
    45. Ciplea AI, Langer-Gould A, de Vries A, Schaap T, Thiel S, Ringelstein M, Gold R, Hellwig K. Monoclonal antibody treatment during pregnancy and/or lactation in women with MS or neuromyelitis optica spectrum disorder. Neurol Neuroimmunol Neuroinflamm. 2020 07 02; 7(4). PMID: 32327455; PMCID: PMC7188475.
      Citations: 29     Fields:    Translation:Humans
    46. Langer-Gould A, Smith JB, Albers KB, Xiang AH, Wu J, Kerezsi EH, McClearnen K, Gonzales EG, Leimpeter AD, Van Den Eeden SK. Pregnancy-related relapses and breastfeeding in a contemporary multiple sclerosis cohort. Neurology. 2020 05 05; 94(18):e1939-e1949. PMID: 32284359; PMCID: PMC7274922.
      Citations: 39     Fields:    Translation:Humans
    47. Alping P, Askling J, Burman J, Fink K, Fogdell-Hahn A, Gunnarsson M, Hillert J, Langer-Gould A, Lycke J, Nilsson P, Salzer J, Svenningsson A, Vrethem M, Olsson T, Piehl F, Frisell T. Cancer Risk for Fingolimod, Natalizumab, and Rituximab in Multiple Sclerosis Patients. Ann Neurol. 2020 05; 87(5):688-699. PMID: 32056253.
      Citations: 49     Fields:    Translation:Humans
    48. Amezcua L, Smith JB, Gonzales EG, Haraszti S, Langer-Gould A. Race, ethnicity, and cognition in persons newly diagnosed with multiple sclerosis. Neurology. 2020 04 07; 94(14):e1548-e1556. PMID: 32152131; PMCID: PMC7251526.
      Citations: 13     Fields:    Translation:Humans
    49. Luna G, Alping P, Burman J, Fink K, Fogdell-Hahn A, Gunnarsson M, Hillert J, Langer-Gould A, Lycke J, Nilsson P, Salzer J, Svenningsson A, Vrethem M, Olsson T, Piehl F, Frisell T. Infection Risks Among Patients With Multiple Sclerosis Treated With Fingolimod, Natalizumab, Rituximab, and Injectable Therapies. JAMA Neurol. 2020 02 01; 77(2):184-191. PMID: 31589278; PMCID: PMC6784753.
      Citations: 214     Fields:    Translation:Humans
    50. Russell RD, Langer-Gould A, Gonzales EG, Smith JB, Brennan V, Pereira G, Lucas RM, Begley A, Black LJ. Obesity, dieting, and multiple sclerosis. Mult Scler Relat Disord. 2019 Dec 09; 39:101889. PMID: 31838309.
      Citations: 9     Fields:    
    51. Langer-Gould A, Black LJ, Waubant E, Smith JB, Wu J, Gonzales EG, Shao X, Koebnick C, Lucas RM, Xiang A, Barcellos LF. Seafood, fatty acid biosynthesis genes, and multiple sclerosis susceptibility. Mult Scler. 2020 10; 26(12):1476-1485. PMID: 33063621; PMCID: PMC7573200.
      Citations: 16     Fields:    Translation:Humans
    52. Waubant E, Lucas R, Mowry E, Graves J, Olsson T, Alfredsson L, Langer-Gould A. Environmental and genetic risk factors for MS: an integrated review. Ann Clin Transl Neurol. 2019 09; 6(9):1905-1922. PMID: 31392849; PMCID: PMC6764632.
      Citations: 114     Fields:    Translation:HumansPHPublic Health
    53. Langer-Gould AM. Pregnancy and Family Planning in Multiple Sclerosis. Continuum (Minneap Minn). 2019 Jun; 25(3):773-792. PMID: 31162316.
      Citations: 22     Fields:    Translation:Humans
    54. Alping P, Piehl F, Langer-Gould A, Frisell T, COMBAT-MS Study Group. Validation of the Swedish Multiple Sclerosis Register: Further Improving a Resource for Pharmacoepidemiologic Evaluations. Epidemiology. 2019 03; 30(2):230-233. PMID: 30721167; PMCID: PMC6369893.
      Citations: 31     Fields:    Translation:Humans
    55. Wallin MT, Culpepper WJ, Campbell JD, Nelson LM, Langer-Gould A, Marrie RA, Cutter GR, Kaye WE, Wagner L, Tremlett H, Buka SL, Dilokthornsakul P, Topol B, Chen LH, LaRocca NG, US Multiple Sclerosis Prevalence Workgroup. The prevalence of MS in the United States: A population-based estimate using health claims data. Neurology. 2019 03 05; 92(10):e1029-e1040. PMID: 30770430; PMCID: PMC6442006.
      Citations: 398     Fields:    Translation:Humans
    56. Culpepper WJ, Marrie RA, Langer-Gould A, Wallin MT, Campbell JD, Nelson LM, Kaye WE, Wagner L, Tremlett H, Chen LH, Leung S, Evans C, Yao S, LaRocca NG, United States Multiple Sclerosis Prevalence Workgroup (MSPWG). Validation of an algorithm for identifying MS cases in administrative health claims datasets. Neurology. 2019 03 05; 92(10):e1016-e1028. PMID: 30770432; PMCID: PMC6442008.
      Citations: 41     Fields:    Translation:Humans
    57. Nelson LM, Wallin MT, Marrie RA, Culpepper WJ, Langer-Gould A, Campbell J, Buka S, Tremlett H, Cutter G, Kaye W, Wagner L, Larocca NG, United States Multiple Sclerosis Prevalence Workgroup. A new way to estimate neurologic disease prevalence in the United States: Illustrated with MS. Neurology. 2019 03 05; 92(10):469-480. PMID: 30770422; PMCID: PMC6442012.
      Citations: 25     Fields:    Translation:Humans
    58. Chi C, Shao X, Rhead B, Gonzales E, Smith JB, Xiang AH, Graves J, Waldman A, Lotze T, Schreiner T, Weinstock-Guttman B, Aaen G, Tillema JM, Ness J, Candee M, Krupp L, Gorman M, Benson L, Chitnis T, Mar S, Belman A, Casper TC, Rose J, Moodley M, Rensel M, Rodriguez M, Greenberg B, Kahn L, Rubin J, Schaefer C, Waubant E, Langer-Gould A, Barcellos LF. Admixture mapping reveals evidence of differential multiple sclerosis risk by genetic ancestry. PLoS Genet. 2019 01; 15(1):e1007808. PMID: 30653506.
      Citations: 32     Fields:    Translation:Humans
    59. Langer-Gould A, Lucas RM. Vitamin D deficiency is an etiological factor for MS - No. Mult Scler. 2019 04; 25(5):639-641. PMID: 30499745.
      Citations: 1     Fields:    Translation:Humans
    60. Langer-Gould A, Lucas R, Xiang AH, Chen LH, Wu J, Gonzalez E, Haraszti S, Smith JB, Quach H, Barcellos LF. MS Sunshine Study: Sun Exposure But Not Vitamin D Is Associated with Multiple Sclerosis Risk in Blacks and Hispanics. Nutrients. 2018 Feb 27; 10(3). PMID: 29495467.
      Citations: 34     Fields:    Translation:Humans
    61. Langer-Gould A, Lucas RM, Xiang AH, Wu J, Chen LH, Gonzales E, Haraszti S, Smith JB, Quach H, Barcellos LF. Vitamin D-Binding Protein Polymorphisms, 25-Hydroxyvitamin D, Sunshine and Multiple Sclerosis. Nutrients. 2018 Feb 07; 10(2). PMID: 29414925.
      Citations: 17     Fields:    Translation:Humans
    62. Langer-Gould A, Wu J, Lucas R, Smith J, Gonzales E, Amezcua L, Haraszti S, Chen LH, Quach H, James JA, Barcellos LF, Xiang AH. Epstein-Barr virus, cytomegalovirus, and multiple sclerosis susceptibility: A multiethnic study. Neurology. 2017 Sep 26; 89(13):1330-1337. PMID: 28855411.
      Citations: 44     Fields:    Translation:HumansCellsPHPublic Health
    63. Langer-Gould A, Smith JB, Hellwig K, Gonzales E, Haraszti S, Koebnick C, Xiang A. Breastfeeding, ovulatory years, and risk of multiple sclerosis. Neurology. 2017 Aug 08; 89(6):563-569. PMID: 28701499.
      Citations: 19     Fields:    Translation:Humans
    64. Obiwuru O, Joseph S, Liu L, Palomeque A, Tarlow L, Langer-Gould AM, Amezcua L. Perceptions of Multiple Sclerosis in Hispanic Americans: Need for Targeted Messaging. Int J MS Care. 2017 May-Jun; 19(3):131-139. PMID: 28603461.
      Citations: 4     
    65. Hellwig K, Langer-Gould AM. Breastfeeding and Disease-Modifying Therapy for Multiple Sclerosis--Reply. JAMA Neurol. 2016 Apr; 73(4):480-1. PMID: 26926044.
      Citations:    Fields:    Translation:Humans
    66. Hellwig K, Chen LH, Stancyzk FZ, Langer-Gould AM. Oral Contraceptives and Multiple Sclerosis/Clinically Isolated Syndrome Susceptibility. PLoS One. 2016; 11(3):e0149094. PMID: 26950301.
      Citations: 20     Fields:    Translation:Humans
    67. Thiel S, Langer-Gould A, Rockhoff M, Haghikia A, Queisser-Wahrendorf A, Gold R, Hellwig K. Interferon-beta exposure during first trimester is safe in women with multiple sclerosis-A prospective cohort study from the German Multiple Sclerosis and Pregnancy Registry. Mult Scler. 2016 05; 22(6):801-9. PMID: 26920382.
      Citations: 44     Fields:    Translation:Humans
    68. Herbstritt S, Langer-Gould A, Rockhoff M, Haghikia A, Queisser-Wahrendorf A, Gold R, Hellwig K. Glatiramer acetate during early pregnancy: A prospective cohort study. Mult Scler. 2016 05; 22(6):810-6. PMID: 26754804.
      Citations: 35     Fields:    Translation:Humans
    69. Langer-Gould A. Sex hormones and multiple sclerosis: another informative failure. Lancet Neurol. 2016 Jan; 15(1):22-3. PMID: 26621681.
      Citations: 4     Fields:    Translation:Humans
    70. Hellwig K, Rockhoff M, Herbstritt S, Borisow N, Haghikia A, Elias-Hamp B, Menck S, Gold R, Langer-Gould A. Exclusive Breastfeeding and the Effect on Postpartum Multiple Sclerosis Relapses. JAMA Neurol. 2015 Oct; 72(10):1132-8. PMID: 26322399.
      Citations: 52     Fields:    Translation:Humans
    71. Langer-Gould A. Association between vaccines and neuroinflammation-reply. JAMA Neurol. 2015 May; 72(5):605. PMID: 25961177.
      Citations:    Fields:    Translation:HumansPHPublic Health
    72. Amezcua L, Conti DV, Liu L, Ledezma K, Langer-Goulda AM. Place of birth,age of immigration,and disability in Hispanics with multiple sclerosis. Mult Scler Relat Disord. 2015 Jan; 4(1):25-30. PMID: 25729639.
      Citations: 9     Fields:    Translation:Humans
    73. Langer-Gould A, Qian L, Tartof SY, Brara SM, Jacobsen SJ, Beaber BE, Sy LS, Chao C, Hechter R, Tseng HF. Vaccines and the risk of multiple sclerosis and other central nervous system demyelinating diseases. JAMA Neurol. 2014 Dec; 71(12):1506-13. PMID: 25329096.
      Citations: 71     Fields:    Translation:HumansPHPublic Health
    74. Henson LJ, Cavalier S, Langer-Gould AM. The pill times 2: what every woman with multiple sclerosis should know. Neurology. 2014 Oct 28; 83(18):1685. PMID: 25349277.
      Citations:    Fields:    Translation:Humans
    75. Haghikia A, Langer-Gould A, Rellensmann G, Schneider H, Tenenbaum T, Elias-Hamp B, Menck S, Zimmermann J, Herbstritt S, Marziniak M, Kümpfel T, Meinl I, Plavina T, Gold R, Hellwig K. Natalizumab use during the third trimester of pregnancy. JAMA Neurol. 2014 Jul 01; 71(7):891-5. PMID: 24821217.
      Citations: 54     Fields:    Translation:HumansAnimals
    76. Langer-Gould A, Brara SM, Beaber BE, Zhang JL. The incidence of clinically isolated syndrome in a multi-ethnic cohort. J Neurol. 2014 Jul; 261(7):1349-55. PMID: 24777692.
      Citations: 11     Fields:    Translation:Humans
    77. Getahun D, Fassett MJ, Longstreth GF, Koebnick C, Langer-Gould AM, Strickland D, Jacobsen SJ. Association between maternal inflammatory bowel disease and adverse perinatal outcomes. J Perinatol. 2014 Jun; 34(6):435-40. PMID: 24651735.
      Citations: 14     Fields:    Translation:Humans
    78. Langer-Gould AM. The pill times 2: what every woman with multiple sclerosis should know. Neurology. 2014 Feb 25; 82(8):654-5. PMID: 24463629.
      Citations: 4     Fields:    Translation:Humans
    79. Beaber BE, Chi MD, Brara SM, Zhang JL, Langer-Gould AM. Immunomodulatory agents and risk of postpartum multiple sclerosis relapses. Perm J. 2014; 18(1):9-13. PMID: 24626066.
      Citations: 6     Fields:    Translation:HumansPHPublic Health
    80. Langer-Gould A, Hellwig K. One can prevent post-partum MS relapses by exclusive breast feeding: yes. Mult Scler. 2013 Oct; 19(12):1567-8. PMID: 24132002.
      Citations: 10     Fields:    Translation:Humans
    81. Mattson DH, Lisak RP, Jones DE, Corboy JR, Larson R, Gronseth G, Getchius TS, Langer-Gould A, Langer-Gould AM, Gronseth GS, Larson R, Getchius TS. The American Academy of Neurology's top five Choosing Wisely recommendations. Neurology. 2013 Sep 10; 81(11):1022-3. PMID: 24019388.
      Citations: 2     Fields:    Translation:Humans
    82. Amezcua L, Lerner A, Ledezma K, Conti D, Law M, Weiner L, Langer-Gould A. Spinal cord lesions and disability in Hispanics with multiple sclerosis. J Neurol. 2013 Nov; 260(11):2770-6. PMID: 23912723.
      Citations: 7     Fields:    Translation:Humans
    83. Langer-Gould A, Brara SM, Beaber BE, Zhang JL. Incidence of multiple sclerosis in multiple racial and ethnic groups. Neurology. 2013 May 07; 80(19):1734-9. PMID: 23650231.
      Citations: 100     Fields:    Translation:Humans
    84. Langer-Gould AM. Reply: To PMID 22633290. J Pediatr. 2013 May; 162(5):1084. PMID: 23453770.
      Citations:    Fields:    Translation:Humans
    85. Langer-Gould AM, Anderson WE, Armstrong MJ, Cohen AB, Eccher MA, Iverson DJ, Potrebic SB, Becker A, Larson R, Gedan A, Getchius TS, Gronseth GS. The American Academy of Neurology's top five choosing wisely recommendations. Neurology. 2013 Sep 10; 81(11):1004-11. PMID: 23430685.
      Citations: 31     Fields:    Translation:Humans
    86. Langer-Gould A, Brara SM, Beaber BE, Koebnick C. Childhood obesity and risk of pediatric multiple sclerosis and clinically isolated syndrome. Neurology. 2013 Feb 05; 80(6):548-52. PMID: 23365063.
      Citations: 100     Fields:    Translation:Humans
    87. Langer-Gould A, Beaber BE. Effects of pregnancy and breastfeeding on the multiple sclerosis disease course. Clin Immunol. 2013 Nov; 149(2):244-50. PMID: 23434027.
      Citations: 15     Fields:    Translation:Humans
    88. Brara SM, Koebnick C, Porter AH, Langer-Gould A. Pediatric idiopathic intracranial hypertension and extreme childhood obesity. J Pediatr. 2012 Oct; 161(4):602-7. PMID: 22633290.
      Citations: 28     Fields:    Translation:Humans
    89. Amezcua L, Chung RH, Conti DV, Langer-Gould AM. Vitamin D levels in Hispanics with multiple sclerosis. J Neurol. 2012 Dec; 259(12):2565-70. PMID: 22588255.
      Citations: 9     Fields:    Translation:Humans
    90. Koebnick C, Langer-Gould AM, Gould MK, Chao CR, Iyer RL, Smith N, Chen W, Jacobsen SJ. Sociodemographic characteristics of members of a large, integrated health care system: comparison with US Census Bureau data. Perm J. 2012; 16(3):37-41. PMID: 23012597.
      Citations: 358     Fields:    Translation:Humans
    91. Langer-Gould A, Zhang JL, Chung J, Yeung Y, Waubant E, Yao J. Incidence of acquired CNS demyelinating syndromes in a multiethnic cohort of children. Neurology. 2011 Sep 20; 77(12):1143-8. PMID: 21865580.
      Citations: 60     Fields:    Translation:HumansPHPublic Health
    92. Nielsen AS, Miravalle A, Langer-Gould A, Cooper J, Edwards KR, Kinkel RP. Maximally tolerated versus minimally effective dose: the case of rituximab in multiple sclerosis. Mult Scler. 2012 Mar; 18(3):377-8. PMID: 21828201.
      Citations: 11     Fields:    Translation:HumansCellsCTClinical Trials
    93. Smith N, Iyer RL, Langer-Gould A, Getahun DT, Strickland D, Jacobsen SJ, Chen W, Derose SF, Koebnick C. Health plan administrative records versus birth certificate records: quality of race and ethnicity information in children. BMC Health Serv Res. 2010 Nov 23; 10:316. PMID: 21092309.
      Citations: 38     Fields:    Translation:Humans
    94. Langer-Gould A, Huang S, Van Den Eeden SK, Gupta R, Leimpeter AD, Albers KB, Horst R, Hollis B, Steinman L, Nelson LM. Vitamin D, pregnancy, breastfeeding, and postpartum multiple sclerosis relapses. Arch Neurol. 2011 Mar; 68(3):310-3. PMID: 21059988.
      Citations: 10     Fields:    Translation:Humans
    95. Langer-Gould A, Albers KB, Van Den Eeden SK, Nelson LM. Autoimmune diseases prior to the diagnosis of multiple sclerosis: a population-based case-control study. Mult Scler. 2010 Jul; 16(7):855-61. PMID: 20463037.
      Citations: 50     Fields:    Translation:Humans
    96. Langer-Gould A, Gupta R, Huang S, Hagan A, Atkuri K, Leimpeter AD, Albers KB, Greenwood E, Van Den Eeden SK, Steinman L, Nelson LM. Interferon-gamma-producing T cells, pregnancy, and postpartum relapses of multiple sclerosis. Arch Neurol. 2010 Jan; 67(1):51-7. PMID: 20065129.
      Citations: 27     Fields:    Translation:HumansCells
    97. Langer-Gould A, Huang SM, Gupta R, Leimpeter AD, Greenwood E, Albers KB, Van Den Eeden SK, Nelson LM. Exclusive breastfeeding and the risk of postpartum relapses in women with multiple sclerosis. Arch Neurol. 2009 Aug; 66(8):958-63. PMID: 19506118.
      Citations: 62     Fields:    Translation:Humans
    98. Smith CH, Waubant E, Langer-Gould A. Absence of neuromyelitis optica IgG antibody in an active relapsing-remitting multiple sclerosis population. J Neuroophthalmol. 2009 Jun; 29(2):104-6. PMID: 19491632.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    99. Hauser SL, Waubant E, Arnold DL, Vollmer T, Antel J, Fox RJ, Bar-Or A, Panzara M, Sarkar N, Agarwal S, Langer-Gould A, Smith CH. B-cell depletion with rituximab in relapsing-remitting multiple sclerosis. N Engl J Med. 2008 Feb 14; 358(7):676-88. PMID: 18272891.
      Citations: 933     Fields:    Translation:HumansCellsCTClinical Trials
    100. Langer-Gould A, Popat RA, Huang SM, Cobb K, Fontoura P, Gould MK, Nelson LM. Clinical and demographic predictors of long-term disability in patients with relapsing-remitting multiple sclerosis: a systematic review. Arch Neurol. 2006 Dec; 63(12):1686-91. PMID: 17172607.
      Citations: 59     Fields:    Translation:Humans
    101. Langer-Gould A, Steinman L. Progressive multifocal leukoencephalopathy and multiple sclerosis: lessons from natalizumab. Curr Neurol Neurosci Rep. 2006 May; 6(3):253-8. PMID: 16635435.
      Citations: 7     Fields:    Translation:HumansCells
    102. Langer-Gould A, Steinman L. What went wrong in the natalizumab trials? Lancet. 2006 Mar 04; 367(9512):708-10. PMID: 16517256.
      Citations: 5     Fields:    Translation:Humans
    103. Langer-Gould A, Atlas SW, Green AJ, Bollen AW, Pelletier D. Progressive multifocal leukoencephalopathy in a patient treated with natalizumab. N Engl J Med. 2005 Jul 28; 353(4):375-81. PMID: 15947078.
      Citations: 348     Fields:    Translation:HumansCells
    104. Langer-Gould A, Moses HH, Murray TJ. Strategies for managing the side effects of treatments for multiple sclerosis. Neurology. 2004 Dec 14; 63(11 Suppl 5):S35-41. PMID: 15596735.
      Citations: 16     Fields:    Translation:Humans
    105. Adalsteinsson E, Langer-Gould A, Homer RJ, Rao A, Sullivan EV, Lima CA, Pfefferbaum A, Atlas SW. Gray matter N-acetyl aspartate deficits in secondary progressive but not relapsing-remitting multiple sclerosis. AJNR Am J Neuroradiol. 2003 Nov-Dec; 24(10):1941-5. PMID: 14625214.
      Citations: 17     Fields:    Translation:Humans
    106. Langer-Gould A, Garren H, Slansky A, Ruiz PJ, Steinman L. Late pregnancy suppresses relapses in experimental autoimmune encephalomyelitis: evidence for a suppressive pregnancy-related serum factor. J Immunol. 2002 Jul 15; 169(2):1084-91. PMID: 12097417.
      Citations: 36     Fields:    Translation:AnimalsCellsPHPublic Health
    107. Lock C, Hermans G, Pedotti R, Brendolan A, Schadt E, Garren H, Langer-Gould A, Strober S, Cannella B, Allard J, Klonowski P, Austin A, Lad N, Kaminski N, Galli SJ, Oksenberg JR, Raine CS, Heller R, Steinman L. Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nat Med. 2002 May; 8(5):500-8. PMID: 11984595.
      Citations: 628     Fields:    Translation:HumansAnimalsCells
    108. Ruiz PJ, Garren H, Hirschberg DL, Langer-Gould AM, Levite M, Karpuj MV, Southwood S, Sette A, Conlon P, Steinman L. Microbial epitopes act as altered peptide ligands to prevent experimental autoimmune encephalomyelitis. J Exp Med. 1999 Apr 19; 189(8):1275-84. PMID: 10209044.
      Citations: 13     Fields:    Translation:AnimalsCells
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