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Rulin C Hechter, MD, PhD

TitleAssistant Investigator
InstitutionKaiser Permanente Southern California
DepartmentDepartment of Research and Evaluation
Address100 South Los Robles Avenue
Pasadena CA 91101
ORCID ORCID Icon0000-0001-8684-6506 Additional info
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    Dr. Hechter has three main areas of focus in her research: 1) Prevention of and treatment for sexually transmitted infections and HIV/AIDS, HIV- associated cardiovascular disease and aging, impact of psychiatric disorders and substance abuse on HIV care engagement, and disparities in HIV treatment adherence and outcomes. 2) Chronic care model and sustainable interventions to improve substance abuse treatment outcomes and provide integrated care for individuals with substance use disorders who also have other serious co-occurring chronic conditions or infections and 3) The safety and effectiveness of vaccines, and the influence of policy and systemic intervention on vaccine uptake in children and adults. She is the principal investigator of a CDC-funded study to evaluate syphilis treatment response in an HIV/syphilis co­infected population, and the co-investigator (site PI) of a National Institute of Nursing Research-funded study to explore contextual factors and disparities in HIV testing, linkage, and retention in care. Dr. Hechter also serves as site PI on a National Institute on Drug Abuse-funded study to implement and evaluate effectiveness of an innovative system that incorporates motivational interviewing and service matching in addiction treatment and utilizes a standard web-based real-time assessment tool to improve patient engagement. She is site PI of the Addiction Research Network (ARN) within the HMORN (Health Maintenance Organization Research Network).

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chang JJ, Bruxvoort K, Chen LH, Akhavan B, Rodriguez J, Hechter RC. Brief Report: COVID-19 Testing, Characteristics, and Outcomes Among People Living With HIV in an Integrated Health System. J Acquir Immune Defic Syndr. 2021 09 01; 88(1):1-5. PMID: 34397741; PMCID: PMC8356847.
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    2. Bruxvoort KJ, Schumacher CM, Towner W, Jones J, Contreras R, Ling Grant D, Hechter RC. Referral Linkage to Preexposure Prophylaxis Care and Persistence on Preexposure Prophylaxis in an Integrated Health Care System. J Acquir Immune Defic Syndr. 2021 Jul 01; 87(3):918-927. PMID: 33633035.
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    3. Kharbanda EO, Vazquez-Benitez G, DeSilva MB, Naleway AL, Klein NP, Hechter RC, Glanz JM, Donahue JG, Jackson LA, Sheth SS, Greenberg V, Panagiotakopoulos L, Mba-Jonas A, Lipkind HS. Association of Inadvertent 9-Valent Human Papillomavirus Vaccine in Pregnancy With Spontaneous Abortion and Adverse Birth Outcomes. JAMA Netw Open. 2021 04 01; 4(4):e214340. PMID: 33818618; PMCID: PMC8022219.
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    4. Storholm ED, Siconolfi D, Huang W, Towner W, Grant DL, Martos A, Chang JM, Hechter R. Project SLIP: Implementation of a PrEP Screening and Linkage Intervention in Primary Care. AIDS Behav. 2021 Aug; 25(8):2348-2357. PMID: 33624193.
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    5. Tsui JI, Akosile MA, Lapham GT, Boudreau DM, Johnson EA, Bobb JF, Binswanger IA, Yarborough BJH, Glass JE, Rossom RC, Murphy MT, Cunningham CO, Arnsten JH, Thakral M, Saxon AJ, Merrill JO, Samet JH, Bart GB, Campbell CI, Loree AM, Silva A, Stotts AL, Ahmedani B, Braciszewski JM, Hechter RC, Northrup TF, Horigian VE, Bradley KA. Prevalence and Medication Treatment of Opioid Use Disorder Among Primary Care Patients with Hepatitis C and HIV. J Gen Intern Med. 2021 04; 36(4):930-937. PMID: 33569735; PMCID: PMC8041979.
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    6. Cheetham TC, Dublin S, Pocobelli G, Bobb JF, Andrade S, Hechter RC, Portugal C, Munis M, Albertson-Junkans L, Salgado G, Wong L, Maarup TJ, Carroll K, Griffin MR, Raebel MA, Smith D, Li DK, Pawloski PA, Toh S, Taylor L, Hua W, Dinatale M, Ceresa C, Trinidad JP, Boudreau DM. Validity of diagnosis and procedure codes for identifying neural tube defects in infants. Pharmacoepidemiol Drug Saf. 2020 11; 29(11):1489-1493. PMID: 32929845.
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    7. Marcus JL, Leyden WA, Alexeeff SE, Anderson AN, Hechter RC, Hu H, Lam JO, Towner WJ, Yuan Q, Horberg MA, Silverberg MJ. Comparison of Overall and Comorbidity-Free Life Expectancy Between Insured Adults With and Without HIV Infection, 2000-2016. JAMA Netw Open. 2020 06 01; 3(6):e207954. PMID: 32539152; PMCID: PMC7296391.
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    8. Boudreau DM, Lapham G, Johnson EA, Bobb JF, Matthews AG, McCormack J, Liu D, Campbell CI, Rossom RC, Binswanger IA, Yarborough BJ, Arnsten JH, Cunningham CO, Glass JE, Murphy MT, Zare M, Hechter RC, Ahmedani B, Braciszewski JM, Horigian VE, Szapocznik J, Samet JH, Saxon AJ, Schwartz RP, Bradley KA. Documented opioid use disorder and its treatment in primary care patients across six U.S. health systems. J Subst Abuse Treat. 2020 03; 112S:41-48. PMID: 32220410; PMCID: PMC7107675.
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    9. Owen-Smith A, Stewart C, Sesay MM, Strasser SM, Yarborough BJ, Ahmedani B, Miller-Matero LR, Waring SC, Haller IV, Waitzfelder BE, Sterling SA, Campbell CI, Hechter RC, Zeber JE, Copeland LA, Scherrer JF, Rossom R, Simon G. Chronic pain diagnoses and opioid dispensings among insured individuals with serious mental illness. BMC Psychiatry. 2020 01 31; 20(1):40. PMID: 32005200; PMCID: PMC6995196.
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    10. Donahue JG, Kieke BA, Lewis EM, Weintraub ES, Hanson KE, McClure DL, Vickers ER, Gee J, Daley MF, DeStefano F, Hechter RC, Jackson LA, Klein NP, Naleway AL, Nelson JC, Belongia EA. Near Real-Time Surveillance to Assess the Safety of the 9-Valent Human Papillomavirus Vaccine. Pediatrics. 2019 12; 144(6). PMID: 31740498; PMCID: PMC7780202.
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    11. Donahue JG, Kieke BA, King JP, Mascola MA, Shimabukuro TT, DeStefano F, Hanson KE, McClure DL, Olaiya O, Glanz JM, Hechter RC, Irving SA, Jackson LA, Klein NP, Naleway AL, Weintraub ES, Belongia EA. Inactivated influenza vaccine and spontaneous abortion in the Vaccine Safety Datalink in 2012-13, 2013-14, and 2014-15. Vaccine. 2019 10 16; 37(44):6673-6681. PMID: 31540812; PMCID: PMC6906603.
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    12. Hojilla JC, Marcus J, Volk JE, Leyden W, Hare CB, Hechter RC, Edelman EJ, Silverberg M, Satre DD. Alcohol and drug use, partner PrEP use and STI prevalence among people with HIV. Sex Transm Infect. 2020 05; 96(3):184-188. PMID: 31444278; PMCID: PMC7035986.
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    13. Hechter RC, Qian L, Tartof SY, Sy LS, Klein NP, Weintraub E, Mercado C, Naleway A, McLean HQ, Jacobsen SJ. Vaccine safety in HIV-infected adults within the Vaccine Safety Datalink Project. Vaccine. 2019 05 31; 37(25):3296-3302. PMID: 31064675; PMCID: PMC6538462.
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    14. Hechter RC, Horberg MA, Weisner C, Campbell CI, Contreras R, Chen LH, Yarborough BJH, Lapham GT, Haller IV, Ahmedani BK, Binswanger IA, Kline-Simon AH, Satre DD. Healthcare Effectiveness Data and Information Set (HEDIS) measures of alcohol and drug treatment initiation and engagement among people living with the human immunodeficiency virus (HIV) and patients without an HIV diagnosis. Subst Abus. 2019 Mar 25; 1-9. PMID: 30908174.
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    15. Kline-Simon AH, Stumbo SP, Campbell CI, Binswanger IA, Weisner C, Haller IV, Hechter RC, Ahmedani BK, Lapham GT, Loree AM, Sterling SA, Yarborough BJH. Patient characteristics associated with treatment initiation and engagement among individuals diagnosed with alcohol and other drug use disorders in emergency department and primary care settings. Subst Abus. 2019 Jan 31; 1-7. PMID: 30702983.
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    16. Loree AM, Yeh HH, Satre DD, Kline-Simon AH, Jo H Yarborough B, Haller IV, Campbell CI, Lapham GT, Hechter RC, Binswanger IA, Weisner C, Ahmedani BK. Psychiatric comorbidity and Healthcare Effectiveness Data and Information Set (HEDIS) measures of alcohol and other drug treatment initiation and engagement across 7 health care systems. Subst Abus. 2019 Jan 25; 1-7. PMID: 30681938.
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    17. Weisner C, Campbell CI, Altschuler A, Yarborough BJH, Lapham GT, Binswanger IA, Hechter RC, Ahmedani BK, Haller IV, Sterling SA, McCarty D, Satre DD, Kline-Simon AH. Factors associated with Healthcare Effectiveness Data and Information Set (HEDIS) alcohol and other drug measure performance in 2014-2015. Subst Abus. 2019 Jan 24; 1-11. PMID: 30676915.
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    18. Campbell CI, Weisner C, Binswanger IA, Lapham GT, Ahmedani BK, Yarborough BJH, Haller IV, Altschuler A, Hechter RC, Loree AM, Kline-Simon AH. Predictors of Healthcare Effectiveness Data and Information Set (HEDIS) treatment initiation and engagement among patients with opioid use disorder across 7 health systems. Subst Abus. 2019 Jan 24; 1-7. PMID: 30676931.
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    19. Binswanger IA, Carroll NM, Ahmedani BK, Campbell CI, Haller IV, Hechter RC, McNeely J, Yarborough BJH, Kline-Simon AH, Satre DD, Weisner C, Lapham GT. The association between medical comorbidity and Healthcare Effectiveness Data and Information Set (HEDIS) measures of treatment initiation and engagement for alcohol and other drug use disorders. Subst Abus. 2019 Jan 24; 1-10. PMID: 30676892.
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    20. Lapham GT, Campbell CI, Yarborough BJH, Hechter RC, Ahmedani BK, Haller IV, Kline-Simon AH, Satre DD, Loree AM, Weisner C, Binswanger IA. The prevalence of Healthcare Effectiveness Data and Information Set (HEDIS) initiation and engagement in treatment among patients with cannabis use disorders in 7?US health systems. Subst Abus. 2019 Jan 18; 1-10. PMID: 30657438.
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    21. Tartof SY, Qian L, Liu IA, Tseng HF, Sy LS, Hechter RC, Lewin BJ, Jacobsen SJ. Safety of Influenza Vaccination Administered During Hospitalization. Mayo Clin Proc. 2019 Mar; 94(3):397-407. PMID: 30635116.
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    22. Kharbanda EO, Vazquez-Benitez G, Lipkind HS, Sheth SS, Zhu J, Naleway AL, Klein NP, Hechter R, Daley MF, Donahue JG, Jackson ML, Kawai AT, Sukumaran L, Nordin JD. Risk of Spontaneous Abortion After Inadvertent Human Papillomavirus Vaccination in Pregnancy. Obstet Gynecol. 2018 Jul; 132(1):35-44. PMID: 29889760.
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    23. Hechter RC, Qian L, Luo Y, Ling Grant DS, Baxter R, Klein NP, Valdez Nunley K, Aukes L, Hogea C, Krishnarajah G, Patterson BJ, Im TM, Tseng HF. Impact of an electronic medical record reminder on hepatitis B vaccine initiation and completion rates among insured adults with diabetes mellitus. Vaccine. 2019 Jan 03; 37(1):195-201. PMID: 29958736.
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    24. Sukumaran L, McCarthy NL, Kharbanda EO, Vazquez-Benitez G, Lipkind HS, Jackson L, Klein NP, Naleway AL, McClure DL, Hechter RC, Kawai AT, Glanz JM, Weintraub ES. Infant Hospitalizations and Mortality After Maternal Vaccination. Pediatrics. 2018 03; 141(3). PMID: 29463582.
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    25. Hechter RC, Bider-Canfield Z, Towner W. Effect of an Electronic Alert on Targeted HIV Testing Among High-Risk Populations. Perm J. 2018; 22:18-015. PMID: 30285916.
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    26. Tartof SY, Sy LS, Ackerson BK, Hechter RC, Haag M, Slezak JM, Luo Y, Fischetti CA, Takhar HS, Miao Y, Solano Z, Jacobsen SJ, Tseng HF. Safety of Quadrivalent Meningococcal Conjugate Vaccine in Children 2-10 Years. Pediatr Infect Dis J. 2017 Nov; 36(11):1087-1092. PMID: 28719502.
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    27. Lipkind HS, Vazquez-Benitez G, Nordin JD, Romitti PA, Naleway AL, Klein NP, Hechter RC, Jackson ML, Hambidge SJ, Lee GM, Sukumaran L, Kharbanda EO. Maternal and Infant Outcomes After Human Papillomavirus Vaccination in the Periconceptional Period or During Pregnancy. Obstet Gynecol. 2017 09; 130(3):599-608. PMID: 28796684.
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    28. Hechter RC, Qian L, Yan S, Luo Y, Krishnarajah G, Tseng HF. Impact of the change of copay policy in Medicare Part D on zoster vaccine uptake among Medicare beneficiaries in a managed care organization. BMC Health Serv Res. 2017 07 21; 17(1):503. PMID: 28732518.
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    29. Ackerson B, Hechter R, Sidell M, Sy LS, Slezak J, Chao C, Patel N, Tseng HF, Jacobsen S. Human papillomavirus vaccine series completion in boys before and after recommendation for routine immunization. Vaccine. 2017 02 07; 35(6):897-902. PMID: 28094077.
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    30. Tseng HF, Sy LS, Ackerson BK, Hechter RC, Tartof SY, Haag M, Slezak JM, Luo Y, Fischetti CA, Takhar HS, Miao Y, Cunnington M, Solano Z, Jacobsen SJ. Safety of Quadrivalent Meningococcal Conjugate Vaccine in 11- to 21-Year-Olds. Pediatrics. 2017 01; 139(1). PMID: 28025240.
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    31. Tartof SY, Qian L, Rieg GK, Yu KC, Sy LS, Tseng HF, Hechter RC, Jacobsen SJ. Safety of Seasonal Influenza Vaccination in Hospitalized Surgical Patients: A Cohort Study. Ann Intern Med. 2016 05 03; 164(9):593-9. PMID: 26974053.
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    32. Tseng HF, Harpaz R, Luo Y, Hales CM, Sy LS, Tartof SY, Bialek S, Hechter RC, Jacobsen SJ. Declining Effectiveness of Herpes Zoster Vaccine in Adults Aged =60 Years. J Infect Dis. 2016 06 15; 213(12):1872-5. PMID: 26908728.
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    33. McCarthy NL, Gee J, Sukumaran L, Weintraub E, Duffy J, Kharbanda EO, Baxter R, Irving S, King J, Daley MF, Hechter R, McNeil MM. Vaccination and 30-Day Mortality Risk in Children, Adolescents, and Young Adults. Pediatrics. 2016 Mar; 137(3):e20152970. PMID: 26908690.
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    34. Tseng HF, Luo Y, Shi J, Sy LS, Tartof SY, Sim JJ, Hechter RC, Jacobsen SJ. Effectiveness of Herpes Zoster Vaccine in Patients 60 Years and Older With End-stage Renal Disease. Clin Infect Dis. 2016 Feb 15; 62(4):462-7. PMID: 26671505.
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    35. Hechter RC, Chao CR, Sidell MA, Sy LS, Ackerson BK, Slezak JM, Patel NJ, Tseng HF, Jacobsen SJ. Quadrivalent Human Papillomavirus Vaccine Initiation in Boys Before and Since Routine Use: Southern California, 2009-2013. Am J Public Health. 2015 Dec; 105(12):2549-56. PMID: 26469643.
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    36. Ackerson BK, Sy LS, Slezak J, Chao CR, Hechter RC, Takhar HS, Jacobsen SJ. Unmasking in an observational vaccine safety study: Using type 2 diabetes mellitus as an example. Vaccine. 2015 Nov 17; 33(46):6224-6. PMID: 26440925.
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    37. Cheetham TC, Niu F, Chiang K, Yuan Y, Kalsekar A, Hechter R, Hay JW, Nyberg L. Factors Associated with Failure to Achieve SVR in Hepatitis C Genotype 3 Patients Within an Integrated Care Delivery System. J Manag Care Spec Pharm. 2015 Aug; 21(8):641-7. PMID: 26233536.
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    38. Klein NP, Lewis E, Fireman B, Hambidge SJ, Naleway A, Nelson JC, Belongia EA, Yih WK, Nordin JD, Hechter RC, Weintraub E, Baxter R. Safety of measles-containing vaccines in 1-year-old children. Pediatrics. 2015 Feb; 135(2):e321-9. PMID: 25560438.
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    39. Langer-Gould A, Qian L, Tartof SY, Brara SM, Jacobsen SJ, Beaber BE, Sy LS, Chao C, Hechter R, Tseng HF. Vaccines and the risk of multiple sclerosis and other central nervous system demyelinating diseases. JAMA Neurol. 2014 Dec; 71(12):1506-13. PMID: 25329096.
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    40. Tartof SY, Tseng HF, Liu IL, Qian L, Sy LS, Hechter RC, Marcy SM, Jacobsen SJ. Inpatient admission for febrile seizure and subsequent outcomes do not differ in children with vaccine-associated versus non-vaccine associated febrile seizures. Vaccine. 2014 Nov 12; 32(48):6408-14. PMID: 25285882.
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    41. Tseng HF, Tartof S, Harpaz R, Luo Y, Sy LS, Hetcher RC, Jacobsen SJ. Vaccination against zoster remains effective in older adults who later undergo chemotherapy. Clin Infect Dis. 2014 Oct; 59(7):913-9. PMID: 25097079.
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    42. Tartof SY, Tseng HF, Liu AL, Qian L, Sy LS, Hechter RC, Marcy SM, Jacobsen SJ. Exploring the risk factors for vaccine-associated and non-vaccine associated febrile seizures in a large pediatric cohort. Vaccine. 2014 May 07; 32(22):2574-81. PMID: 24674662.
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    43. Hechter RC, Jacobsen SJ, Luo Y, Nomura JH, Towner WJ, Tartof SY, Tseng HF. Hepatitis B testing and vaccination among adults with sexually transmitted infections in a large managed care organization. Clin Infect Dis. 2014 Jun; 58(12):1739-45. PMID: 24571863.
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    44. Hechter RC, Tartof SY, Jacobsen SJ, Smith N, Tseng HF. Trends and disparity in zoster vaccine uptake in a managed care population. Vaccine. 2013 Sep 23; 31(41):4564-8. PMID: 23928461.
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    45. Hechter RC, Chao C, Sy LS, Ackerson BK, Slezak JM, Sidell MA, Jacobsen SJ. Quadrivalent human papillomavirus vaccine uptake in adolescent boys and maternal utilization of preventive care and history of sexually transmitted infections. Am J Public Health. 2013 Sep; 103(9):e63-8. PMID: 23865707.
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    46. Chen LH, Quinn V, Xu L, Gould MK, Jacobsen SJ, Koebnick C, Reynolds K, Hechter RC, Chao CR. The accuracy and trends of smoking history documentation in electronic medical records in a large managed care organization. Subst Use Misuse. 2013 Jun; 48(9):731-42. PMID: 23621678.
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    47. Hechter RC, Qian L, Sy LS, Greene SK, Weintraub ES, Naleway AL, Rowhani-Rahbar A, Donahue JG, Daley MF, Vazquez-Benitez G, Lugg MM, Jacobsen SJ. Secular trends in diagnostic code density in electronic healthcare data from health care systems in the Vaccine Safety Datalink project. Vaccine. 2013 Feb 04; 31(7):1080-5. PMID: 23267842.
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    48. Hechter RC, Chao C, Jacobsen SJ, Slezak JM, Quinn VP, Van Den Eeden SK, Tseng HF. Clinical effectiveness of pneumococcal polysaccharide vaccine in men: California Men's Health Study. Vaccine. 2012 Aug 17; 30(38):5625-30. PMID: 22789510.
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    49. Hechter RC, Chao C, Li Q, Jacobsen SJ, Tseng HF. Correlates for second-dose varicella vaccination in school-age children in a managed care organization in California. Pediatr Infect Dis J. 2012 Jul; 31(7):752-5. PMID: 22466321.
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    50. Hechter RC, Budoff M, Hodis HN, Rinaldo CR, Jenkins FJ, Jacobson LP, Kingsley LA, Taiwo B, Post WS, Margolick JB, Detels R. Herpes simplex virus type 2 (HSV-2) as a coronary atherosclerosis risk factor in HIV-infected men: multicenter AIDS cohort study. Atherosclerosis. 2012 Aug; 223(2):433-6. PMID: 22472456.
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    51. Hechter RC, Chao C, Li Q, Jacobsen SJ, Tseng HF. Second-dose varicella vaccination coverage in children and adolescents in a managed care organization in California, 2006-2009. Pediatr Infect Dis J. 2011 Aug; 30(8):705-7. PMID: 21283048.
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    52. Kalantar-Zadeh K, Shah A, Duong U, Hechter RC, Dukkipati R, Kovesdy CP. Kidney bone disease and mortality in CKD: revisiting the role of vitamin D, calcimimetics, alkaline phosphatase, and minerals. Kidney Int Suppl. 2010 Aug; (117):S10-21. PMID: 20671739.
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