Receptors, N-Methyl-D-Aspartate
"Receptors, N-Methyl-D-Aspartate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity.
| Descriptor ID |
D016194
|
| MeSH Number(s) |
D12.776.157.530.400.400.500.500 D12.776.543.550.450.500.200.500 D12.776.543.585.400.500.200.500 D12.776.543.750.720.200.450.400.500
|
| Concept/Terms |
Receptors, N-Methyl-D-Aspartate- Receptors, N-Methyl-D-Aspartate
- Receptors, N Methyl D Aspartate
- N-Methyl-D-Aspartate Receptors
- N Methyl D Aspartate Receptors
- NMDA Receptors
- Receptors, N-Methylaspartate
- Receptors, N Methylaspartate
- Receptors, NMDA
- NMDA Receptor-Ionophore Complex
- NMDA Receptor Ionophore Complex
- N-Methylaspartate Receptors
- N Methylaspartate Receptors
|
Below are MeSH descriptors whose meaning is more general than "Receptors, N-Methyl-D-Aspartate".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Receptors, Ionotropic Glutamate [D12.776.157.530.400.400.500]
- Receptors, N-Methyl-D-Aspartate [D12.776.157.530.400.400.500.500]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.450]
- Ligand-Gated Ion Channels [D12.776.543.550.450.500]
- Receptors, Ionotropic Glutamate [D12.776.543.550.450.500.200]
- Receptors, N-Methyl-D-Aspartate [D12.776.543.550.450.500.200.500]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Receptors, Ionotropic Glutamate [D12.776.543.585.400.500.200]
- Receptors, N-Methyl-D-Aspartate [D12.776.543.585.400.500.200.500]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Amino Acid [D12.776.543.750.720.200]
- Receptors, Glutamate [D12.776.543.750.720.200.450]
- Receptors, Ionotropic Glutamate [D12.776.543.750.720.200.450.400]
- Receptors, N-Methyl-D-Aspartate [D12.776.543.750.720.200.450.400.500]
Below are MeSH descriptors whose meaning is more specific than "Receptors, N-Methyl-D-Aspartate".
This graph shows the total number of publications written about "Receptors, N-Methyl-D-Aspartate" by people in this website by year, and whether "Receptors, N-Methyl-D-Aspartate" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, N-Methyl-D-Aspartate" by people in Profiles.
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Successful pharmacotherapy for the treatment of severe feeding aversion with mechanistic insights from cross-species neuronal remodeling. Transl Psychiatry. 2017 06 20; 7(6):e1157.
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Elevated prenatal homocysteine levels as a risk factor for schizophrenia. Arch Gen Psychiatry. 2007 Jan; 64(1):31-9.
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Absence of binding activity of neuron-restrictive silencer factor is necessary, but not sufficient for transcription of NMDA receptor subunit type 1 in neuronal cells. Brain Res Mol Brain Res. 1999 Dec 10; 74(1-2):44-54.