Histocompatibility Antigens Class I
"Histocompatibility Antigens Class I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells.
| Descriptor ID |
D015395
|
| MeSH Number(s) |
D12.776.395.550.489 D12.776.543.550.439 D23.050.301.500.100 D23.050.705.552.100
|
| Concept/Terms |
Histocompatibility Antigens Class I- Histocompatibility Antigens Class I
- Class I Histocompatibility Antigens
- Class I Antigens
- Antigens, Class I
- I Antigens, Class
- Class I Major Histocompatibility Antigens
|
Below are MeSH descriptors whose meaning is more general than "Histocompatibility Antigens Class I".
Below are MeSH descriptors whose meaning is more specific than "Histocompatibility Antigens Class I".
This graph shows the total number of publications written about "Histocompatibility Antigens Class I" by people in this website by year, and whether "Histocompatibility Antigens Class I" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 2 | 0 | 2 |
| 2013 | 1 | 1 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Histocompatibility Antigens Class I" by people in Profiles.
-
Penetrance of Hemochromatosis in HFE Genotypes Resulting in p.Cys282Tyr and p.[Cys282Tyr];[His63Asp] in the eMERGE Network. Am J Hum Genet. 2015 Oct 01; 97(4):512-20.
-
Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects. PLoS Genet. 2013 Nov; 9(11):e1003926.
-
Modification by hemochromatosis gene polymorphisms of the association between traffic-related air pollution and cognition in older men: a cohort study. Environ Health. 2013 Feb 15; 12:16.
-
Serial serum ferritin measurements in untreated HFE C282Y homozygotes in the Hemochromatosis and Iron Overload Screening Study. Int J Lab Hematol. 2008 Aug; 30(4):300-5.
-
Hemochromatosis gene status as a risk factor for Barrett's esophagus. Dig Dis Sci. 2008 Dec; 53(12):3095-102.
-
The contribution of HLA class I antigens in immune status following two doses of rubella vaccination. Hum Immunol. 2004 Dec; 65(12):1506-15.
-
Lack of association between transporter associated with antigen processing (TAP) and HLA-DM gene polymorphisms and antibody levels following measles vaccination. Eur J Immunogenet. 2003 Jun; 30(3):195-200.
-
The association of class I HLA alleles and antibody levels after a single dose of measles vaccine. Hum Immunol. 2003 Jan; 64(1):103-9.
-
Comprehensive analysis of human leukocyte antigen class I alleles and cervical neoplasia in 3 epidemiologic studies. J Infect Dis. 2002 Sep 01; 186(5):598-605.
-
Associations between human leukocyte antigen homozygosity and antibody levels to measles vaccine. J Infect Dis. 2002 Jun 01; 185(11):1545-9.