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Hélène Choquet, PhD

TitleResearch Scientist II
InstitutionKaiser Permanente Northern California
DepartmentDivision of Research
Address2000 Broadway
Oakland CA 94612
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Gorman BR, Francis M, Nealon CL, Halladay CW, Duro N, Markianos K, Genovese G, Hysi PG, Choquet H, Afshari NA, Li YJ, VA Million Veteran Program, Gaziano JM, Hung AM, Wu WC, Greenberg PB, Pyarajan S, Lass JH, Peachey NS, Iyengar SK. A multi-ancestry GWAS of Fuchs corneal dystrophy highlights the contributions of laminins, collagen, and endothelial cell regulation. Commun Biol. 2024 Apr 06; 7(1):418. PMID: 38582945; PMCID: PMC10998918.
      Citations:    
    2. Choquet H, Jiang C, Yin J, Kim Y, Hoffmann TJ, 23andMe Research Team, Jorgenson E, Asgari MM. Multi-ancestry genome-wide meta-analysis identifies novel basal cell carcinoma loci and shared genetic effects with squamous cell carcinoma. Commun Biol. 2024 01 05; 7(1):33. PMID: 38182794; PMCID: PMC10770328.
      Citations:    
    3. Lee T, George CD, Jiang C, Asgari MM, Nijsten T, Pardo LM, Choquet H. Association between lifetime smoking and cutaneous squamous cell carcinoma: A 2-sample Mendelian randomization study. JAAD Int. 2024 Mar; 14:69-76. PMID: 38274396; PMCID: PMC10808986.
      Citations:    
    4. Cowan B, Kvale M, Yin J, Patel S, Jorgenson E, Mostaedi R, Choquet H. Risk factors for inguinal hernia repair among US adults. Hernia. 2023 Nov 10. PMID: 37947923.
      Citations:    
    5. Budu-Aggrey A, Kilanowski A, Sobczyk MK, 23andMe Research Team, Shringarpure SS, Mitchell R, Reis K, Reigo A, Estonian Biobank Research Team, M?gi R, Nelis M, Tanaka N, Brumpton BM, Thomas LF, Sole-Navais P, Flatley C, Espuela-Ortiz A, Herrera-Luis E, Lominchar JVT, Bork-Jensen J, Marenholz I, Arnau-Soler A, Jeong A, Fawcett KA, Baurecht H, Rodriguez E, Alves AC, Kumar A, Sleiman PM, Chang X, Medina-Gomez C, Hu C, Xu CJ, Qi C, El-Heis S, Titcombe P, Antoun E, Fadista J, Wang CA, Thiering E, Wu B, Kress S, Kothalawala DM, Kadalayil L, Duan J, Zhang H, Hadebe S, Hoffmann T, Jorgenson E, Choquet H, Risch N, Nj?lstad P, Andreassen OA, Johansson S, Almqvist C, Gong T, Ullemar V, Karlsson R, Magnusson PKE, Szwajda A, Burchard EG, Thyssen JP, Hansen T, K?rhus LL, Dantoft TM, Jeanrenaud ACSN, Ghauri A, Arnold A, Homuth G, Lau S, N?then MM, H?bner N, Imboden M, Visconti A, Falchi M, Bataille V, Hysi P, Ballardini N, Boomsma DI, Hottenga JJ, M?ller-Nurasyid M, Ahluwalia TS, Stokholm J, Chawes B, Schoos AM, Esplugues A, Bustamante M, Raby B, Arshad S, German C, Esko T, Milani LA, Metspalu A, Terao C, Abuabara K, L?set M, Hveem K, Jacobsson B, Pino-Yanes M, Strachan DP, Grarup N, Linneberg A, Lee YA, Probst-Hensch N, Weidinger S, Jarvelin MR, Mel?n E, Hakonarson H, Irvine AD, Jarvis D, Nijsten T, Duijts L, Vonk JM, Koppelmann GH, Godfrey KM, Barton SJ, Feenstra B, Pennell CE, Sly PD, Holt PG, Williams LK, Bisgaard H, B?nnelykke K, Curtin J, Simpson A, Murray C, Schikowski T, Bunyavanich S, Weiss ST, Holloway JW, Min JL, Brown SJ, Standl M, Paternoster L. European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation. Nat Commun. 2023 10 04; 14(1):6172. PMID: 37794016; PMCID: PMC10550990.
      Citations:    
    6. Jiang C, Melles RB, Sangani P, Hoffmann TJ, Hysi PG, Glymour MM, Jorgenson E, Lachke SA, Choquet H. Association of Behavioral and Clinical Risk Factors With Cataract: A Two-Sample Mendelian Randomization Study. Invest Ophthalmol Vis Sci. 2023 07 03; 64(10):19. PMID: 37459064; PMCID: PMC10362921.
      Citations:    Fields:    Translation:Humans
    7. Han X, Gharahkhani P, Hamel AR, Ong JS, Renter?a ME, Mehta P, Dong X, Pasutto F, Hammond C, Young TL, Hysi P, Lotery AJ, Jorgenson E, Choquet H, Hauser M, Cooke Bailey JN, Nakazawa T, Akiyama M, Shiga Y, Fuller ZL, Wang X, Hewitt AW, Craig JE, Pasquale LR, Mackey DA, Wiggs JL, Khawaja AP, Segr? AV, 23andMe Research Team, International Glaucoma Genetics Consortium, MacGregor S. Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci. Nat Genet. 2023 07; 55(7):1116-1125. PMID: 37386247; PMCID: PMC10335935.
      Citations:    Fields:    Translation:Humans
    8. Meyers TJ, Yin J, Herrera VA, Pressman AR, Hoffmann TJ, Schaefer C, Avins AL, Choquet H. Transcriptome-wide association study identifies novel candidate susceptibility genes for migraine. HGG Adv. 2023 Jul 13; 4(3):100211. PMID: 37415806; PMCID: PMC10319829.
      Citations:    Translation:HumansCells
    9. Jiang C, Melles RB, Yin J, Fan Q, Guo X, Cheng CY, He M, Mackey DA, Guggenheim JA, Klaver C, Consortium for Refractive Error and Myopia (CREAM), Nair KS, Jorgenson E, Choquet H. A multiethnic genome-wide analysis of 19,420 individuals identifies novel loci associated with axial length and shared genetic influences with refractive error and myopia. Front Genet. 2023; 14:1113058. PMID: 37351342; PMCID: PMC10282939.
      Citations:    
    10. Peachey N, Gorman B, Francis M, Nealon C, Halladay C, Duro N, Markianos K, Genovese G, Hysi P, Choquet H, Afshari N, Li YJ, Gaziano JM, Hung A, Wu WC, Greenberg P, Pyarajan S, Lass J, Iyengar S. Multi-ancestry GWAS of Fuchs corneal dystrophy highlights roles of laminins, collagen, and endothelial cell regulation. Res Sq. 2023 May 03. PMID: 37205546; PMCID: PMC10187421.
      Citations:    
    11. Gao XR, Chiariglione M, Choquet H, Arch AJ. 10?Years of GWAS in intraocular pressure. Front Genet. 2023; 14:1130106. PMID: 37124618; PMCID: PMC10130654.
      Citations:    
    12. Clark R, Lee SS, Du R, Wang Y, Kneepkens SCM, Charng J, Huang Y, Hunter ML, Jiang C, Tideman JWL, Melles RB, Klaver CCW, Mackey DA, Williams C, Choquet H, Ohno-Matsui K, Guggenheim JA, CREAM Consortium, UK Biobank Eye and Vision Consortium. A new polygenic score for refractive error improves detection of children at risk of high myopia but not the prediction of those at risk of myopic macular degeneration. EBioMedicine. 2023 May; 91:104551. PMID: 37055258; PMCID: PMC10203044.
      Citations:    Fields:    Translation:Humans
    13. Saunders GRB, Wang X, Chen F, Jang SK, Liu M, Wang C, Gao S, Jiang Y, Khunsriraksakul C, Otto JM, Addison C, Akiyama M, Albert CM, Aliev F, Alonso A, Arnett DK, Ashley-Koch AE, Ashrani AA, Barnes KC, Barr RG, Bartz TM, Becker DM, Bielak LF, Benjamin EJ, Bis JC, Bjornsdottir G, Blangero J, Bleecker ER, Boardman JD, Boerwinkle E, Boomsma DI, Boorgula MP, Bowden DW, Brody JA, Cade BE, Chasman DI, Chavan S, Chen YI, Chen Z, Cheng I, Cho MH, Choquet H, Cole JW, Cornelis MC, Cucca F, Curran JE, de Andrade M, Dick DM, Docherty AR, Duggirala R, Eaton CB, Ehringer MA, Esko T, Faul JD, Fernandes Silva L, Fiorillo E, Fornage M, Freedman BI, Gabrielsen ME, Garrett ME, Gharib SA, Gieger C, Gillespie N, Glahn DC, Gordon SD, Gu CC, Gu D, Gudbjartsson DF, Guo X, Haessler J, Hall ME, Haller T, Harris KM, He J, Herd P, Hewitt JK, Hickie I, Hidalgo B, Hokanson JE, Hopfer C, Hottenga J, Hou L, Huang H, Hung YJ, Hunter DJ, Hveem K, Hwang SJ, Hwu CM, Iacono W, Irvin MR, Jee YH, Johnson EO, Joo YY, Jorgenson E, Justice AE, Kamatani Y, Kaplan RC, Kaprio J, Kardia SLR, Keller MC, Kelly TN, Kooperberg C, Korhonen T, Kraft P, Krauter K, Kuusisto J, Laakso M, Lasky-Su J, Lee WJ, Lee JJ, Levy D, Li L, Li K, Li Y, Lin K, Lind PA, Liu C, Lloyd-Jones DM, Lutz SM, Ma J, M?gi R, Manichaikul A, Martin NG, Mathur R, Matoba N, McArdle PF, McGue M, McQueen MB, Medland SE, Metspalu A, Meyers DA, Millwood IY, Mitchell BD, Mohlke KL, Moll M, Montasser ME, Morrison AC, Mulas A, Nielsen JB, North KE, Oelsner EC, Okada Y, Orr? V, Palmer ND, Palviainen T, Pandit A, Park SL, Peters U, Peters A, Peyser PA, Polderman TJC, Rafaels N, Redline S, Reed RM, Reiner AP, Rice JP, Rich SS, Richmond NE, Roan C, Rotter JI, Rueschman MN, Runarsdottir V, Saccone NL, Schwartz DA, Shadyab AH, Shi J, Shringarpure SS, Sicinski K, Skogholt AH, Smith JA, Smith NL, Sotoodehnia N, Stallings MC, Stefansson H, Stefansson K, Stitzel JA, Sun X, Syed M, Tal-Singer R, Taylor AE, Taylor KD, Telen MJ, Thai KK, Tiwari H, Turman C, Tyrfingsson T, Wall TL, Walters RG, Weir DR, Weiss ST, White WB, Whitfield JB, Wiggins KL, Willemsen G, Willer CJ, Winsvold BS, Xu H, Yanek LR, Yin J, Young KL, Young KA, Yu B, Zhao W, Zhou W, Z?llner S, Zuccolo L, 23andMe Research Team, Biobank Japan Project, Batini C, Bergen AW, Bierut LJ, David SP, Gagliano Taliun SA, Hancock DB, Jiang B, Munaf? MR, Thorgeirsson TE, Liu DJ, Vrieze S. Genetic diversity fuels gene discovery for tobacco and alcohol use. Nature. 2022 12; 612(7941):720-724. PMID: 36477530; PMCID: PMC9771818.
      Citations: 14     Fields:    Translation:HumansCells
    14. Kim Y, Yin J, Le Breton S, Jorgenson E, Huang H, Choquet H, Asgari MM. Genetically Predicted Serum Vitamin C Levels and Cutaneous Squamous Cell Carcinoma Risk. J Invest Dermatol. 2022 Nov 05. PMID: 36343677.
      Citations:    Fields:    Translation:Humans
    15. Choquet H, Khawaja AP, Jiang C, Yin J, Melles RB, Glymour MM, Hysi PG, Jorgenson E. Association Between Myopic Refractive Error and Primary Open-Angle Glaucoma: A 2-Sample Mendelian Randomization Study. JAMA Ophthalmol. 2022 09 01; 140(9):864-871. PMID: 35900730; PMCID: PMC9335248.
      Citations: 5     Fields:    Translation:Humans
    16. Kim Y, Yin J, Huang H, Jorgenson E, Choquet H, Asgari MM. Genome-wide association study of actinic keratosis identifies new susceptibility loci implicated in pigmentation and immune regulation pathways. Commun Biol. 2022 04 21; 5(1):386. PMID: 35449187; PMCID: PMC9023580.
      Citations: 4     Translation:Humans
    17. Choquet H, Li W, Yin J, Bradley R, Hoffmann TJ, Nandakumar P, 23andMe Research Team, Mostaedi R, Tian C, Ahituv N, Jorgenson E. Ancestry- and sex-specific effects underlying inguinal hernia susceptibility identified in a multiethnic genome-wide association study meta-analysis. Hum Mol Genet. 2022 Jan 12. PMID: 35022708.
      Citations: 2     Fields:    Translation:Humans
    18. Simcoe MJ, Shah A, Fan B, Choquet H, Weisschuh N, Waseem NH, Jiang C, Melles RB, Ritch R, Mahroo OA, Wissinger B, Jorgenson E, Wiggs JL, Garway-Heath DF, Hysi PG, Hammond CJ. GWAS identifies two common loci associated with pigment dispersion syndrome/pigmentary glaucoma and implicate myopia in its development. Ophthalmology. 2022 Jan 11. PMID: 35031440.
      Citations: 3     Fields:    Translation:Humans
    19. Tapia AL, Rowland BT, Rosen JD, Preuss M, Young K, Graff M, Choquet H, Couper DJ, Buyske S, Bien SA, Jorgenson E, Kooperberg C, Loos RJF, Morrison AC, North KE, Yu B, Reiner AP, Li Y, Raffield LM. Full title: A large-scale transcriptome-wide association study (TWAS) of 10 blood cell phenotypes reveals complexities of TWAS fine-mapping. Genet Epidemiol. 2022 Feb; 46(1):3-16. PMID: 34779012.
      Citations: 2     Fields:    Translation:HumansCells
    20. Currant H, Hysi P, Fitzgerald TW, Gharahkhani P, Bonnemaijer PWM, Senabouth A, Hewitt AW, UK Biobank Eye and Vision Consortium, International Glaucoma Genetics Consortium, Atan D, Aung T, Charng J, Choquet H, Craig J, Khaw PT, Klaver CCW, Kubo M, Ong JS, Pasquale LR, Reisman CA, Daniszewski M, Powell JE, Pébay A, Simcoe MJ, Thiadens AAHJ, van Duijn CM, Yazar S, Jorgenson E, MacGregor S, Hammond CJ, Mackey DA, Wiggs JL, Foster PJ, Patel PJ, Birney E, Khawaja AP. Correction: Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images. PLoS Genet. 2021 Oct; 17(10):e1009858. PMID: 34662343; PMCID: PMC8523050.
      Citations: 1     Fields:    
    21. Mikhaylova AV, McHugh CP, Polfus LM, Raffield LM, Boorgula MP, Blackwell TW, Brody JA, Broome J, Chami N, Chen MH, Conomos MP, Cox C, Curran JE, Daya M, Ekunwe L, Glahn DC, Heard-Costa N, Highland HM, Hobbs BD, Ilboudo Y, Jain D, Lange LA, Miller-Fleming TW, Min N, Moon JY, Preuss MH, Rosen J, Ryan K, Smith AV, Sun Q, Surendran P, de Vries PS, Walter K, Wang Z, Wheeler M, Yanek LR, Zhong X, Abecasis GR, Almasy L, Barnes KC, Beaty TH, Becker LC, Blangero J, Boerwinkle E, Butterworth AS, Chavan S, Cho MH, Choquet H, Correa A, Cox N, DeMeo DL, Faraday N, Fornage M, Gerszten RE, Hou L, Johnson AD, Jorgenson E, Kaplan R, Kooperberg C, Kundu K, Laurie CA, Lettre G, Lewis JP, Li B, Li Y, Lloyd-Jones DM, Loos RJF, Manichaikul A, Meyers DA, Mitchell BD, Morrison AC, Ngo D, Nickerson DA, Nongmaithem S, North KE, O'Connell JR, Ortega VE, Pankratz N, Perry JA, Psaty BM, Rich SS, Soranzo N, Rotter JI, Silverman EK, Smith NL, Tang H, Tracy RP, Thornton TA, Vasan RS, Zein J, Mathias RA, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Reiner AP, Auer PL. Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program. Am J Hum Genet. 2021 10 07; 108(10):1836-1851. PMID: 34582791; PMCID: PMC8546043.
      Citations: 8     Fields:    Translation:HumansCells
    22. Little A, Hu Y, Sun Q, Jain D, Broome J, Chen MH, Thibord F, McHugh C, Surendran P, Blackwell TW, Brody JA, Bhan A, Chami N, Vries PS, Ekunwe L, Heard-Costa N, Hobbs BD, Manichaikul A, Moon JY, Preuss MH, Ryan K, Wang Z, Wheeler M, Yanek LR, Abecasis GR, Almasy L, Beaty TH, Becker LC, Blangero J, Boerwinkle E, Butterworth AS, Choquet H, Correa A, Curran JE, Faraday N, Fornage M, Glahn DC, Hou L, Jorgenson E, Kooperberg C, Lewis JP, Lloyd-Jones DM, Loos RJF, Min N, Mitchell BD, Morrison AC, Nickerson D, North KE, O'Connell JR, Pankratz N, Psaty BM, Vasan RS, Rich SS, Rotter JI, Smith AV, Smith NL, Tang H, Tracy RP, Conomos MP, Laurie CA, Mathias RA, Li Y, Auer PL, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Thornton T, Reiner AP, Johnson AD, Raffield LM. Whole genome sequence analysis of platelet traits in the NHLBI trans-omics for precision medicine initiative. Hum Mol Genet. 2021 Sep 06. PMID: 34553764.
      Citations: 3     Fields:    Translation:HumansCells
    23. Nair KS, Srivastava C, Brown RV, Koli S, Choquet H, Kang HS, Kuo YM, Grimm SA, Sutherland C, Badea A, Johnson GA, Zhao Y, Yin J, Okamoto K, Clark G, Borrás T, Zode G, Kizhatil K, Chakrabarti S, John SWM, Jorgenson E, Jetten AM. GLIS1 regulates trabecular meshwork function and intraocular pressure and is associated with glaucoma in humans. Nat Commun. 2021 08 12; 12(1):4877. PMID: 34385434; PMCID: PMC8361148.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    24. Choquet H, Yin J, Jacobson AS, Horton BH, Hoffmann TJ, Jorgenson E, Avins AL, Pressman AR. New and sex-specific migraine susceptibility loci identified from a multiethnic genome-wide meta-analysis. Commun Biol. 2021 07 22; 4(1):864. PMID: 34294844; PMCID: PMC8298472.
      Citations: 9     Translation:Humans
    25. Wen J, Xie M, Rowland B, Rosen JD, Sun Q, Chen J, Tapia AL, Qian H, Kowalski MH, Shan Y, Young KL, Graff M, Argos M, Avery CL, Bien SA, Buyske S, Yin J, Choquet H, Fornage M, Hodonsky CJ, Jorgenson E, Kooperberg C, Loos RJF, Liu Y, Moon JY, North KE, Rich SS, Rotter JI, Smith JA, Zhao W, Shang L, Wang T, Zhou X, Reiner AP, Raffield LM, Li Y. Transcriptome-Wide Association Study of Blood Cell Traits in African Ancestry and Hispanic/Latino Populations. Genes (Basel). 2021 07 08; 12(7). PMID: 34356065; PMCID: PMC8307403.
      Citations: 4     Fields:    Translation:HumansCells
    26. Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, 23andMe Research Team, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E. A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 06 14; 12(1):3595. PMID: 34127677; PMCID: PMC8203611.
      Citations: 16     Fields:    Translation:HumansAnimals
    27. Hu Y, Stilp AM, McHugh CP, Rao S, Jain D, Zheng X, Lane J, Méric de Bellefon S, Raffield LM, Chen MH, Yanek LR, Wheeler M, Yao Y, Ren C, Broome J, Moon JY, de Vries PS, Hobbs BD, Sun Q, Surendran P, Brody JA, Blackwell TW, Choquet H, Ryan K, Duggirala R, Heard-Costa N, Wang Z, Chami N, Preuss MH, Min N, Ekunwe L, Lange LA, Cushman M, Faraday N, Curran JE, Almasy L, Kundu K, Smith AV, Gabriel S, Rotter JI, Fornage M, Lloyd-Jones DM, Vasan RS, Smith NL, North KE, Boerwinkle E, Becker LC, Lewis JP, Abecasis GR, Hou L, O'Connell JR, Morrison AC, Beaty TH, Kaplan R, Correa A, Blangero J, Jorgenson E, Psaty BM, Kooperberg C, Walton RT, Kleinstiver BP, Tang H, Loos RJF, Soranzo N, Butterworth AS, Nickerson D, Rich SS, Mitchell BD, Johnson AD, Auer PL, Li Y, Mathias RA, Lettre G, Pankratz N, Laurie CC, Laurie CA, Bauer DE, Conomos MP, Reiner AP, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program. Am J Hum Genet. 2021 Jun 03; 108(6):1165. PMID: 34087167; PMCID: PMC8206380.
      Citations: 5     Fields:    
    28. Currant H, Hysi P, Fitzgerald TW, Gharahkhani P, Bonnemaijer PWM, Senabouth A, Hewitt AW, UK Biobank Eye and Vision Consortium, International Glaucoma Genetics Consortium, Atan D, Aung T, Charng J, Choquet H, Craig J, Khaw PT, Klaver CCW, Kubo M, Ong JS, Pasquale LR, Reisman CA, Daniszewski M, Powell JE, Pébay A, Simcoe MJ, Thiadens AAHJ, van Duijn CM, Yazar S, Jorgenson E, MacGregor S, Hammond CJ, Mackey DA, Wiggs JL, Foster PJ, Patel PJ, Birney E, Khawaja AP. Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images. PLoS Genet. 2021 05; 17(5):e1009497. PMID: 33979322; PMCID: PMC8143408.
      Citations: 17     Fields:    Translation:Humans
    29. Hu Y, Stilp AM, McHugh CP, Rao S, Jain D, Zheng X, Lane J, Méric de Bellefon S, Raffield LM, Chen MH, Yanek LR, Wheeler M, Yao Y, Ren C, Broome J, Moon JY, de Vries PS, Hobbs BD, Sun Q, Surendran P, Brody JA, Blackwell TW, Choquet H, Ryan K, Duggirala R, Heard-Costa N, Wang Z, Chami N, Preuss MH, Min N, Ekunwe L, Lange LA, Cushman M, Faraday N, Curran JE, Almasy L, Kundu K, Smith AV, Gabriel S, Rotter JI, Fornage M, Lloyd-Jones DM, Vasan RS, Smith NL, North KE, Boerwinkle E, Becker LC, Lewis JP, Abecasis GR, Hou L, O'Connell JR, Morrison AC, Beaty TH, Kaplan R, Correa A, Blangero J, Jorgenson E, Psaty BM, Kooperberg C, Walton RT, Kleinstiver BP, Tang H, Loos RJF, Soranzo N, Butterworth AS, Nickerson D, Rich SS, Mitchell BD, Johnson AD, Auer PL, Li Y, Mathias RA, Lettre G, Pankratz N, Laurie CC, Laurie CA, Bauer DE, Conomos MP, Reiner AP, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program. Am J Hum Genet. 2021 05 06; 108(5):874-893. PMID: 33887194; PMCID: PMC8206199.
      Citations: 9     Fields:    Translation:HumansCells
    30. Hardcastle AJ, Liskova P, Bykhovskaya Y, McComish BJ, Davidson AE, Inglehearn CF, Li X, Choquet H, Habeeb M, Lucas SEM, Sahebjada S, Pontikos N, Lopez KER, Khawaja AP, Ali M, Dudakova L, Skalicka P, Van Dooren BTH, Geerards AJM, Haudum CW, Faro VL, Tenen A, Simcoe MJ, Patasova K, Yarrand D, Yin J, Siddiqui S, Rice A, Farraj LA, Chen YI, Rahi JS, Krauss RM, Theusch E, Charlesworth JC, Szczotka-Flynn L, Toomes C, Meester-Smoor MA, Richardson AJ, Mitchell PA, Taylor KD, Melles RB, Aldave AJ, Mills RA, Cao K, Chan E, Daniell MD, Wang JJ, Rotter JI, Hewitt AW, MacGregor S, Klaver CCW, Ramdas WD, Craig JE, Iyengar SK, O'Brart D, Jorgenson E, Baird PN, Rabinowitz YS, Burdon KP, Hammond CJ, Tuft SJ, Hysi PG. A multi-ethnic genome-wide association study implicates collagen matrix integrity and cell differentiation pathways in keratoconus. Commun Biol. 2021 03 01; 4(1):266. PMID: 33649486; PMCID: PMC7921564.
      Citations: 11     Translation:HumansCells
    31. Choquet H, Yin J, Jorgenson E. Cigarette smoking behaviors and the importance of ethnicity and genetic ancestry. Transl Psychiatry. 2021 02 11; 11(1):120. PMID: 33633108; PMCID: PMC7907280.
      Citations:    Fields:    Translation:Humans
    32. Young-Wolff KC, Adams SR, Sterling SA, Tan ASL, Salloum RG, Torre K, Carter-Harris L, Prochaska JJ. Nicotine and cannabis vaping among adolescents in treatment for substance use disorders. J Subst Abuse Treat. 2021 06; 125:108304. PMID: 34016296; PMCID: PMC8140195.
      Citations: 3     Fields:    Translation:HumansAnimals
    33. Jorgenson E, Choquet H, Yin J, Hoffmann TJ, Banda Y, Kvale MN, Risch N, Schaefer C, Asgari MM. Genetic ancestry, skin pigmentation, and the risk of cutaneous squamous cell carcinoma in Hispanic/Latino and non-Hispanic white populations. Commun Biol. 2020 12 14; 3(1):765. PMID: 33318654; PMCID: PMC7736583.
      Citations: 2     Translation:Humans
    34. Young-Wolff KC, Wei J, Varnado N, Rios N, Staunton M, Watson C. Adverse Childhood Experiences and Pregnancy Intentions among Pregnant Women Seeking Prenatal Care. Womens Health Issues. 2021 Mar-Apr; 31(2):100-106. PMID: 33032888; PMCID: PMC8005410.
      Citations: 5     Fields:    Translation:Humans
    35. Chen MH, Raffield LM, Mousas A, Sakaue S, Huffman JE, Moscati A, Trivedi B, Jiang T, Akbari P, Vuckovic D, Bao EL, Zhong X, Manansala R, Laplante V, Chen M, Lo KS, Qian H, Lareau CA, Beaudoin M, Hunt KA, Akiyama M, Bartz TM, Ben-Shlomo Y, Beswick A, Bork-Jensen J, Bottinger EP, Brody JA, van Rooij FJA, Chitrala K, Cho K, Choquet H, Correa A, Danesh J, Di Angelantonio E, Dimou N, Ding J, Elliott P, Esko T, Evans MK, Floyd JS, Broer L, Grarup N, Guo MH, Greinacher A, Haessler J, Hansen T, Howson JMM, Huang QQ, Huang W, Jorgenson E, Kacprowski T, Kähönen M, Kamatani Y, Kanai M, Karthikeyan S, Koskeridis F, Lange LA, Lehtimäki T, Lerch MM, Linneberg A, Liu Y, Lyytikäinen LP, Manichaikul A, Martin HC, Matsuda K, Mohlke KL, Mononen N, Murakami Y, Nadkarni GN, Nauck M, Nikus K, Ouwehand WH, Pankratz N, Pedersen O, Preuss M, Psaty BM, Raitakari OT, Roberts DJ, Rich SS, Rodriguez BAT, Rosen JD, Rotter JI, Schubert P, Spracklen CN, Surendran P, Tang H, Tardif JC, Trembath RC, Ghanbari M, Völker U, Völzke H, Watkins NA, Zonderman AB, VA Million Veteran Program, Wilson PWF, Li Y, Butterworth AS, Gauchat JF, Chiang CWK, Li B, Loos RJF, Astle WJ, Evangelou E, van Heel DA, Sankaran VG, Okada Y, Soranzo N, Johnson AD, Reiner AP, Auer PL, Lettre G. Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Cell. 2020 09 03; 182(5):1198-1213.e14. PMID: 32888493; PMCID: PMC7480402.
      Citations: 147     Fields:    Translation:HumansCells
    36. Vuckovic D, Bao EL, Akbari P, Lareau CA, Mousas A, Jiang T, Chen MH, Raffield LM, Tardaguila M, Huffman JE, Ritchie SC, Megy K, Ponstingl H, Penkett CJ, Albers PK, Wigdor EM, Sakaue S, Moscati A, Manansala R, Lo KS, Qian H, Akiyama M, Bartz TM, Ben-Shlomo Y, Beswick A, Bork-Jensen J, Bottinger EP, Brody JA, van Rooij FJA, Chitrala KN, Wilson PWF, Choquet H, Danesh J, Di Angelantonio E, Dimou N, Ding J, Elliott P, Esko T, Evans MK, Felix SB, Floyd JS, Broer L, Grarup N, Guo MH, Guo Q, Greinacher A, Haessler J, Hansen T, Howson JMM, Huang W, Jorgenson E, Kacprowski T, Kähönen M, Kamatani Y, Kanai M, Karthikeyan S, Koskeridis F, Lange LA, Lehtimäki T, Linneberg A, Liu Y, Lyytikäinen LP, Manichaikul A, Matsuda K, Mohlke KL, Mononen N, Murakami Y, Nadkarni GN, Nikus K, Pankratz N, Pedersen O, Preuss M, Psaty BM, Raitakari OT, Rich SS, Rodriguez BAT, Rosen JD, Rotter JI, Schubert P, Spracklen CN, Surendran P, Tang H, Tardif JC, Ghanbari M, Völker U, Völzke H, Watkins NA, Weiss S, VA Million Veteran Program, Cai N, Kundu K, Watt SB, Walter K, Zonderman AB, Cho K, Li Y, Loos RJF, Knight JC, Georges M, Stegle O, Evangelou E, Okada Y, Roberts DJ, Inouye M, Johnson AD, Auer PL, Astle WJ, Reiner AP, Butterworth AS, Ouwehand WH, Lettre G, Sankaran VG, Soranzo N. The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell. 2020 09 03; 182(5):1214-1231.e11. PMID: 32888494; PMCID: PMC7482360.
      Citations: 167     Fields:    Translation:Humans
    37. Young-Wolff KC, Sarovar V, Alexeeff SE, Adams SR, Tucker LY, Conway A, Ansley D, Goler N, Armstrong MA, Weisner C. Trends and correlates of self-reported alcohol and nicotine use among women before and during pregnancy, 2009-2017. Drug Alcohol Depend. 2020 09 01; 214:108168. PMID: 32736316; PMCID: PMC7423641.
      Citations: 4     Fields:    Translation:Humans
    38. Choquet H, Thai KK, Jiang C, Ranatunga DK, Hoffmann TJ, Go AS, Lindsay AC, Ehm MG, Waterworth DM, Risch N, Schaefer C. Meta-Analysis of 26 638 Individuals Identifies Two Genetic Loci Associated With Left Ventricular Ejection Fraction. Circ Genom Precis Med. 2020 08; 13(4):e002804. PMID: 32605384; PMCID: PMC7446727.
      Citations: 5     Fields:    Translation:Humans
    39. Choquet H, Melles RB, Yin J, Hoffmann TJ, Thai KK, Kvale MN, Banda Y, Hardcastle AJ, Tuft SJ, Glymour MM, Schaefer C, Risch N, Nair KS, Hysi PG, Jorgenson E. A multiethnic genome-wide analysis of 44,039 individuals identifies 41 new loci associated with central corneal thickness. Commun Biol. 2020 06 11; 3(1):301. PMID: 32528159; PMCID: PMC7289804.
      Citations: 12     Translation:Humans
    40. Choquet H, Ashrafzadeh S, Kim Y, Asgari MM, Jorgenson E. Genetic and environmental factors underlying keratinocyte carcinoma risk. JCI Insight. 2020 05 21; 5(10). PMID: 32434987; PMCID: PMC7259534.
      Citations: 10     Fields:    Translation:HumansCells
    41. Young-Wolff KC, Tucker LY, Armstrong MA, Conway A, Weisner C, Goler N. Correlates of Pregnant Women's Participation in a Substance Use Assessment and Counseling Intervention Integrated into Prenatal Care. Matern Child Health J. 2020 Apr; 24(4):423-431. PMID: 32056081; PMCID: PMC7187921.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    42. Hysi PG, Choquet H, Khawaja AP, Wojciechowski R, Tedja MS, Yin J, Simcoe MJ, Patasova K, Mahroo OA, Thai KK, Cumberland PM, Melles RB, Verhoeven VJM, Vitart V, Segre A, Stone RA, Wareham N, Hewitt AW, Mackey DA, Klaver CCW, MacGregor S, Consortium for Refractive Error and Myopia, Khaw PT, Foster PJ, UK Eye and Vision Consortium, Guggenheim JA, 23andMe Inc., Rahi JS, Jorgenson E, Hammond CJ. Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia. Nat Genet. 2020 04; 52(4):401-407. PMID: 32231278; PMCID: PMC7145443.
      Citations: 90     Fields:    Translation:Humans
    43. Thompson A, Cook J, Choquet H, Jorgenson E, Yin J, Kinnunen T, Barclay J, Morris AP, Pirmohamed M. Functional validity, role, and implications of heavy alcohol consumption genetic loci. Sci Adv. 2020 01; 6(3):eaay5034. PMID: 31998841; PMCID: PMC6962045.
      Citations: 25     Fields:    Translation:HumansCells
    44. Choquet H, Kim H. Genome-wide Genotyping of Cerebral Cavernous Malformation Type 1 Individuals to Identify Genetic Modifiers of Disease Severity. Methods Mol Biol. 2020; 2152:77-84. PMID: 32524545.
      Citations: 2     Fields:    Translation:Humans
    45. Kowalski MH, Qian H, Hou Z, Rosen JD, Tapia AL, Shan Y, Jain D, Argos M, Arnett DK, Avery C, Barnes KC, Becker LC, Bien SA, Bis JC, Blangero J, Boerwinkle E, Bowden DW, Buyske S, Cai J, Cho MH, Choi SH, Choquet H, Cupples LA, Cushman M, Daya M, de Vries PS, Ellinor PT, Faraday N, Fornage M, Gabriel S, Ganesh SK, Graff M, Gupta N, He J, Heckbert SR, Hidalgo B, Hodonsky CJ, Irvin MR, Johnson AD, Jorgenson E, Kaplan R, Kardia SLR, Kelly TN, Kooperberg C, Lasky-Su JA, Loos RJF, Lubitz SA, Mathias RA, McHugh CP, Montgomery C, Moon JY, Morrison AC, Palmer ND, Pankratz N, Papanicolaou GJ, Peralta JM, Peyser PA, Rich SS, Rotter JI, Silverman EK, Smith JA, Smith NL, Taylor KD, Thornton TA, Tiwari HK, Tracy RP, Wang T, Weiss ST, Weng LC, Wiggins KL, Wilson JG, Yanek LR, Zöllner S, North KE, Auer PL, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Hematology & Hemostasis Working Group, Raffield LM, Reiner AP, Li Y. Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations. PLoS Genet. 2019 12; 15(12):e1008500. PMID: 31869403; PMCID: PMC6953885.
      Citations: 102     Fields:    Translation:Humans
    46. Meyre D, Andress EJ, Sharma T, Snippe M, Asif H, Maharaj A, Vatin V, Gaget S, Besnard P, Choquet H, Froguel P, Linton KJ. Contribution of rare coding mutations in CD36 to type 2 diabetes and cardio-metabolic complications. Sci Rep. 2019 11 20; 9(1):17123. PMID: 31748580; PMCID: PMC6868229.
      Citations: 3     Fields:    Translation:HumansCells
    47. Choquet H, Wiggs JL, Khawaja AP. Clinical implications of recent advances in primary open-angle glaucoma genetics. Eye (Lond). 2020 01; 34(1):29-39. PMID: 31645673; PMCID: PMC7002426.
      Citations: 17     Fields:    Translation:Humans
    48. Young-Wolff KC, Adams SR, Wi S, Weisner C, Conway A. Routes of cannabis administration among females in the year before and during pregnancy: Results from a pilot project. Addict Behav. 2020 01; 100:106125. PMID: 31600645; PMCID: PMC7945962.
      Citations: 20     Fields:    Translation:HumansAnimals
    49. Young-Wolff KC, Sarovar V, Tucker LY, Avalos LA, Alexeeff S, Conway A, Armstrong MA, Weisner C, Campbell CI, Goler N. Trends in marijuana use among pregnant women with and without nausea and vomiting in pregnancy, 2009-2016. Drug Alcohol Depend. 2019 03 01; 196:66-70. PMID: 30711893.
      Citations: 26     Fields:    Translation:Humans
    50. Young-Wolff KC, Adams SR, Fogelberg R, Goldstein AA, Preston PG. Evaluation of a Pilot Perioperative Smoking Cessation Program: A Pre-Post Study. J Surg Res. 2019 May; 237:30-40. PMID: 30694789.
      Citations: 3     Fields:    Translation:Humans
    51. Liu M, Jiang Y, Wedow R, Li Y, Brazel DM, Chen F, Datta G, Davila-Velderrain J, McGuire D, Tian C, Zhan X, Choquet H, Docherty AR, Faul JD, Foerster JR, Fritsche LG, Gabrielsen ME, Gordon SD, Haessler J, Hottenga JJ, Huang H, Jang SK, Jansen PR, Ling Y, Mägi R, Matoba N, McMahon G, Mulas A, Orrù V, Palviainen T, Pandit A, Reginsson GW, Skogholt AH, Smith JA, Taylor AE, Turman C, Willemsen G, Young H, Young KA, Zajac GJM, Zhao W, Zhou W, Bjornsdottir G, Boardman JD, Boehnke M, Boomsma DI, Chen C, Cucca F, Davies GE, Eaton CB, Ehringer MA, Esko T, Fiorillo E, Gillespie NA, Gudbjartsson DF, Haller T, Harris KM, Heath AC, Hewitt JK, Hickie IB, Hokanson JE, Hopfer CJ, Hunter DJ, Iacono WG, Johnson EO, Kamatani Y, Kardia SLR, Keller MC, Kellis M, Kooperberg C, Kraft P, Krauter KS, Laakso M, Lind PA, Loukola A, Lutz SM, Madden PAF, Martin NG, McGue M, McQueen MB, Medland SE, Metspalu A, Mohlke KL, Nielsen JB, Okada Y, Peters U, Polderman TJC, Posthuma D, Reiner AP, Rice JP, Rimm E, Rose RJ, Runarsdottir V, Stallings MC, Stancáková A, Stefansson H, Thai KK, Tindle HA, Tyrfingsson T, Wall TL, Weir DR, Weisner C, Whitfield JB, Winsvold BS, Yin J, Zuccolo L, Bierut LJ, Hveem K, Lee JJ, Munafò MR, Saccone NL, Willer CJ, Cornelis MC, David SP, Hinds DA, Jorgenson E, Kaprio J, Stitzel JA, Stefansson K, Thorgeirsson TE, Abecasis G, Liu DJ, Vrieze S. Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use. Nat Genet. 2019 02; 51(2):237-244. PMID: 30643251.
      Citations: 569     Fields:    Translation:HumansAnimals
    52. Hoffmann TJ, Choquet H, Yin J, Banda Y, Kvale MN, Glymour M, Schaefer C, Risch N, Jorgenson E. A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci. Genetics. 2018 10; 210(2):499-515. PMID: 30108127.
      Citations: 65     Fields:    Translation:Humans
    53. Choquet H, Paylakhi S, Kneeland SC, Thai KK, Hoffmann TJ, Yin J, Kvale MN, Banda Y, Tolman NG, Williams PA, Schaefer C, Melles RB, Risch N, John SWM, Nair KS, Jorgenson E. A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci. Nat Commun. 2018 06 11; 9(1):2278. PMID: 29891935.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    54. Jorgenson E, Choquet H, Yin J, Asgari MM. Common Mitochondrial Haplogroups and Cutaneous Squamous Cell Carcinoma Risk. Cancer Epidemiol Biomarkers Prev. 2018 07; 27(7):838-841. PMID: 29695379.
      Citations: 2     Fields:    Translation:HumansCells
    55. Young-Wolff KC, Klebaner D, Folck B, Tan ASL, Fogelberg R, Sarovar V, Prochaska JJ. Documentation of e-cigarette use and associations with smoking from 2012 to 2015 in an integrated healthcare delivery system. Prev Med. 2018 04; 109:113-118. PMID: 29360481.
      Citations: 17     Fields:    Translation:Humans
    56. Choquet H, Thai KK, Yin J, Hoffmann TJ, Kvale MN, Banda Y, Schaefer C, Risch N, Nair KS, Melles R, Jorgenson E. A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure. Nat Commun. 2017 12 13; 8(1):2108. PMID: 29235454.
      Citations: 44     Fields:    Translation:Humans
    57. Young-Wolff KC, Klebaner D, Folck B, Carter-Harris L, Salloum RG, Prochaska JJ, Fogelberg R, Tan ASL. Do you vape? Leveraging electronic health records to assess clinician documentation of electronic nicotine delivery system use among adolescents and adults. Prev Med. 2017 Dec; 105:32-36. PMID: 28823688.
      Citations: 12     Fields:    Translation:Humans
    58. Jorgenson E, Thai KK, Hoffmann TJ, Sakoda LC, Kvale MN, Banda Y, Schaefer C, Risch N, Mertens J, Weisner C, Choquet H. Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study. Mol Psychiatry. 2017 09; 22(9):1359-1367. PMID: 28485404.
      Citations: 71     Fields:    Translation:Humans
    59. Young-Wolff KC, Kline-Simon AH, Das S, Mordecai DJ, Miller-Rosales C, Weisner C. Smoking Trends Among Adults With Behavioral Health Conditions in Integrated Health Care: A Retrospective Cohort Study. Psychiatr Serv. 2016 09 01; 67(9):996-1003. PMID: 27079992.
      Citations: 4     Fields:    Translation:Humans
    60. Choquet H, Trapani E, Goitre L, Trabalzini L, Akers A, Fontanella M, Hart BL, Morrison LA, Pawlikowska L, Kim H, Retta SF. Cytochrome P450 and matrix metalloproteinase genetic modifiers of disease severity in Cerebral Cavernous Malformation type 1. Free Radic Biol Med. 2016 Mar; 92:100-109. PMID: 26795600; PMCID: PMC4774945.
      Citations: 27     Fields:    Translation:Humans
    61. Choquet H, Pawlikowska L, Lawton MT, Kim H. Genetics of cerebral cavernous malformations: current status and future prospects. J Neurosurg Sci. 2015 Sep; 59(3):211-20. PMID: 25900426; PMCID: PMC4461471.
      Citations: 34     Fields:    Translation:Humans
    62. Young-Wolff KC, Wang P, Tuvblad C, Baker LA, Raine A, Prescott CA. Drinking experience uncovers genetic influences on alcohol expectancies across adolescence. Addiction. 2015 Apr; 110(4):610-8. PMID: 25586461.
      Citations: 9     Fields:    Translation:Humans
    63. Choquet H, Pawlikowska L, Nelson J, McCulloch CE, Akers A, Baca B, Khan Y, Hart B, Morrison L, Kim H, Brain Vascular Malformation Consortium (BVMC) Study. Polymorphisms in inflammatory and immune response genes associated with cerebral cavernous malformation type 1 severity. Cerebrovasc Dis. 2014; 38(6):433-40. PMID: 25472749; PMCID: PMC4297571.
      Citations: 35     Fields:    Translation:Humans
    64. Choquet H, Nelson J, Pawlikowska L, McCulloch CE, Akers A, Baca B, Khan Y, Hart B, Morrison L, Kim H. Association of cardiovascular risk factors with disease severity in cerebral cavernous malformation type 1 subjects with the common Hispanic mutation. Cerebrovasc Dis. 2014; 37(1):57-63. PMID: 24401931; PMCID: PMC3995158.
      Citations: 20     Fields:    Translation:Humans
    65. Choquet H, Joslyn G, Lee A, Kasberger J, Robertson M, Brush G, Schuckit MA, White R, Jorgenson E. Examination of rare missense variants in the CHRNA5-A3-B4 gene cluster to level of response to alcohol in the San Diego Sibling Pair study. Alcohol Clin Exp Res. 2013 Aug; 37(8):1311-6. PMID: 23458267.
      Citations: 11     Fields:    Translation:Humans
    66. Choquet H, Kasberger J, Hamidovic A, Jorgenson E. Contribution of common PCSK1 genetic variants to obesity in 8,359 subjects from multi-ethnic American population. PLoS One. 2013; 8(2):e57857. PMID: 23451278.
      Citations: 14     Fields:    Translation:Humans
    67. Ichimura A, Hirasawa A, Poulain-Godefroy O, Bonnefond A, Hara T, Yengo L, Kimura I, Leloire A, Liu N, Iida K, Choquet H, Besnard P, Lecoeur C, Vivequin S, Ayukawa K, Takeuchi M, Ozawa K, Tauber M, Maffeis C, Morandi A, Buzzetti R, Elliott P, Pouta A, Jarvelin MR, Körner A, Kiess W, Pigeyre M, Caiazzo R, Van Hul W, Van Gaal L, Horber F, Balkau B, Lévy-Marchal C, Rouskas K, Kouvatsi A, Hebebrand J, Hinney A, Scherag A, Pattou F, Meyre D, Koshimizu TA, Wolowczuk I, Tsujimoto G, Froguel P. Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human. Nature. 2012 Feb 19; 483(7389):350-4. PMID: 22343897.
      Citations: 259     Fields:    Translation:HumansAnimalsCells
    68. Creemers JW, Choquet H, Stijnen P, Vatin V, Pigeyre M, Beckers S, Meulemans S, Than ME, Yengo L, Tauber M, Balkau B, Elliott P, Jarvelin MR, Van Hul W, Van Gaal L, Horber F, Pattou F, Froguel P, Meyre D. Heterozygous mutations causing partial prohormone convertase 1 deficiency contribute to human obesity. Diabetes. 2012 Feb; 61(2):383-90. PMID: 22210313; PMCID: PMC3266396.
      Citations: 48     Fields:    Translation:HumansCells
    69. Choquet H, Meyre D. Genetics of Obesity: What have we Learned? Curr Genomics. 2011 May; 12(3):169-79. PMID: 22043165; PMCID: PMC3137002.
      Citations: 76     
    70. Choquet H, Meyre D. Molecular basis of obesity: current status and future prospects. Curr Genomics. 2011 May; 12(3):154-68. PMID: 22043164; PMCID: PMC3137001.
      Citations: 33     
    71. Choquet H, Stijnen P, Creemers JW. Genetic and functional characterization of PCSK1. Methods Mol Biol. 2011; 768:247-53. PMID: 21805247.
      Citations: 6     Fields:    Translation:Humans
    72. Choquet H, Labrune Y, De Graeve F, Hinney A, Hebebrand J, Scherag A, Lecoeur C, Tauber M, Balkau B, Elliot P, Jarvelin MR, Walley AJ, Besnard P, Froguel P, Meyre D. Lack of association of CD36 SNPs with early onset obesity: a meta-analysis in 9,973 European subjects. Obesity (Silver Spring). 2011 Apr; 19(4):833-9. PMID: 20966904.
      Citations: 7     Fields:    Translation:Humans
    73. Choquet H, Meyre D. Genomic insights into early-onset obesity. Genome Med. 2010 Jun 23; 2(6):36. PMID: 20587078; PMCID: PMC2905096.
      Citations: 20     Fields:    
    74. Cauchi S, Del Guerra S, Choquet H, D'Aleo V, Groves CJ, Lupi R, McCarthy MI, Froguel P, Marchetti P. Meta-analysis and functional effects of the SLC30A8 rs13266634 polymorphism on isolated human pancreatic islets. Mol Genet Metab. 2010 May; 100(1):77-82. PMID: 20138556.
      Citations: 42     Fields:    Translation:Humans
    75. Choquet H, Cavalcanti-Proença C, Lecoeur C, Dina C, Cauchi S, Vaxillaire M, Hadjadj S, Horber F, Potoczna N, Charpentier G, Ruiz J, Hercberg S, Maimaitiming S, Roussel R, Boenhnke M, Jackson AU, Patsch W, Krempler F, Voight BF, Altshuler D, Groop L, Thorleifsson G, Steinthorsdottir V, Stefansson K, Balkau B, Froguel P, Meyre D. The T-381C SNP in BNP gene may be modestly associated with type 2 diabetes: an updated meta-analysis in 49 279 subjects. Hum Mol Genet. 2009 Jul 01; 18(13):2495-501. PMID: 19377085.
      Citations: 20     Fields:    Translation:Humans
    76. Bouhaha R, Choquet H, Meyre D, Abid Kamoun H, Ennafaa H, Baroudi T, Sassi R, Vaxillaire M, Elgaaied A, Froguel P, Cauchi S. TCF7L2 is associated with type 2 diabetes in nonobese individuals from Tunisia. Pathol Biol (Paris). 2010 Dec; 58(6):426-9. PMID: 19286335.
      Citations: 8     Fields:    Translation:Humans
    77. Cauchi S, Nead KT, Choquet H, Horber F, Potoczna N, Balkau B, Marre M, Charpentier G, Froguel P, Meyre D. The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies. BMC Med Genet. 2008 May 22; 9:45. PMID: 18498634; PMCID: PMC2412856.
      Citations: 60     Fields:    Translation:Humans
    78. Cauchi S, Meyre D, Durand E, Proença C, Marre M, Hadjadj S, Choquet H, De Graeve F, Gaget S, Allegaert F, Delplanque J, Permutt MA, Wasson J, Blech I, Charpentier G, Balkau B, Vergnaud AC, Czernichow S, Patsch W, Chikri M, Glaser B, Sladek R, Froguel P. Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value. PLoS One. 2008 May 07; 3(5):e2031. PMID: 18461161; PMCID: PMC2346547.
      Citations: 68     Fields:    Translation:Humans
    79. Cauchi S, Choquet H, Gutiérrez-Aguilar R, Capel F, Grau K, Proença C, Dina C, Duval A, Balkau B, Marre M, Potoczna N, Langin D, Horber F, Sørensen TI, Charpentier G, Meyre D, Froguel P. Effects of TCF7L2 polymorphisms on obesity in European populations. Obesity (Silver Spring). 2008 Feb; 16(2):476-82. PMID: 18239663.
      Citations: 45     Fields:    Translation:Humans
    80. Cauchi S, Proença C, Choquet H, Gaget S, De Graeve F, Marre M, Balkau B, Tichet J, Meyre D, Vaxillaire M, Froguel P, D.E.S.I.R. Study Group. Analysis of novel risk loci for type 2 diabetes in a general French population: the D.E.S.I.R. study. J Mol Med (Berl). 2008 Mar; 86(3):341-8. PMID: 18210030.
      Citations: 31     Fields:    Translation:Humans
    81. Cauchi S, Meyre D, Choquet H, Deghmoun S, Durand E, Gaget S, Lecoeur C, Froguel P, Levy-Marchal C. TCF7L2 rs7903146 variant does not associate with smallness for gestational age in the French population. BMC Med Genet. 2007 Jun 25; 8:37. PMID: 17593304; PMCID: PMC1920504.
      Citations: 7     Fields:    Translation:Humans
    82. Cauchi S, El Achhab Y, Choquet H, Dina C, Krempler F, Weitgasser R, Nejjari C, Patsch W, Chikri M, Meyre D, Froguel P. TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis. J Mol Med (Berl). 2007 Jul; 85(7):777-82. PMID: 17476472.
      Citations: 152     Fields:    Translation:Humans
    83. Cauchi S, Vaxillaire M, Choquet H, Durand E, Duval A, Polak M, Froguel P. No major contribution of TCF7L2 sequence variants to maturity onset of diabetes of the young (MODY) or neonatal diabetes mellitus in French white subjects. Diabetologia. 2007 Jan; 50(1):214-6. PMID: 17093940.
      Citations: 8     Fields:    Translation:HumansCells
    84. Cauchi S, Meyre D, Choquet H, Dina C, Born C, Marre M, Balkau B, Froguel P, DESIR Study Group. TCF7L2 variation predicts hyperglycemia incidence in a French general population: the data from an epidemiological study on the Insulin Resistance Syndrome (DESIR) study. Diabetes. 2006 Nov; 55(11):3189-92. PMID: 17065361.
      Citations: 38     Fields:    Translation:Humans
    85. Cauchi S, Meyre D, Dina C, Choquet H, Samson C, Gallina S, Balkau B, Charpentier G, Pattou F, Stetsyuk V, Scharfmann R, Staels B, Frühbeck G, Froguel P. Transcription factor TCF7L2 genetic study in the French population: expression in human beta-cells and adipose tissue and strong association with type 2 diabetes. Diabetes. 2006 Oct; 55(10):2903-8. PMID: 17003360.
      Citations: 132     Fields:    Translation:HumansAnimalsCells
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