Arachidonate 12-Lipoxygenase
"Arachidonate 12-Lipoxygenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-HPETE) which is itself rapidly converted by a peroxidase to 12-hydroxy-5,8,10,14-eicosatetraenoate (12-HETE). The 12-hydroperoxides are preferentially formed in PLATELETS.
| Descriptor ID |
D001092
|
| MeSH Number(s) |
D08.811.682.690.416.583.500.060 D12.776.556.579.374.568.500.025
|
| Concept/Terms |
Arachidonate 12-Lipoxygenase- Arachidonate 12-Lipoxygenase
- 12-Lipoxygenase, Arachidonate
- Arachidonate 12 Lipoxygenase
- Arachidonic Acid 12-Lipoxygenase
- 12-Lipoxygenase, Arachidonic Acid
- Arachidonic Acid 12 Lipoxygenase
- 12-Lipoxygenase
- 12 Lipoxygenase
|
Below are MeSH descriptors whose meaning is more general than "Arachidonate 12-Lipoxygenase".
Below are MeSH descriptors whose meaning is more specific than "Arachidonate 12-Lipoxygenase".
This graph shows the total number of publications written about "Arachidonate 12-Lipoxygenase" by people in this website by year, and whether "Arachidonate 12-Lipoxygenase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Arachidonate 12-Lipoxygenase" by people in Profiles.
-
Genetic variation in the lipoxygenase pathway and risk of colorectal neoplasia. Genes Chromosomes Cancer. 2013 May; 52(5):437-49.
-
A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease. Atherosclerosis. 2008 May; 198(1):136-44.