Arachidonate 5-Lipoxygenase
"Arachidonate 5-Lipoxygenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate (5-HPETE) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-HETE). The 5-hydroperoxides are preferentially formed in leukocytes.
| Descriptor ID |
D001094
|
| MeSH Number(s) |
D08.811.682.690.416.583.500.055 D12.776.556.579.374.568.500.020
|
| Concept/Terms |
Arachidonate 5-Lipoxygenase- Arachidonate 5-Lipoxygenase
- 5-Lipoxygenase, Arachidonate
- Arachidonate 5 Lipoxygenase
- Arachidonic Acid 5-Lipoxygenase
- 5-Lipoxygenase, Arachidonic Acid
- Arachidonic Acid 5 Lipoxygenase
- LTA4 Synthase
- Synthase, LTA4
- Leukotriene A4 Synthase
- Synthase, Leukotriene A4
- Leukotriene A4 Synthetase
- Synthetase, Leukotriene A4
- 5-Lipoxygenase
- 5 Lipoxygenase
- Leukotriene A Synthase
- Synthase, Leukotriene A
|
Below are MeSH descriptors whose meaning is more general than "Arachidonate 5-Lipoxygenase".
Below are MeSH descriptors whose meaning is more specific than "Arachidonate 5-Lipoxygenase".
This graph shows the total number of publications written about "Arachidonate 5-Lipoxygenase" by people in this website by year, and whether "Arachidonate 5-Lipoxygenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Arachidonate 5-Lipoxygenase" by people in Profiles.
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Genetic variation in the lipoxygenase pathway and risk of colorectal neoplasia. Genes Chromosomes Cancer. 2013 May; 52(5):437-49.
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Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease. Hum Genet. 2008 May; 123(4):399-408.