"APOBEC-3G Deaminase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An APOBEC deaminase that functions as an inhibitor of RETROVIRIDAE replication and inhibits the mobility of RETROTRANSPOSONS via deaminase-dependent and independent mechanisms. It is selective for SINGLE-STRANDED DNA and does not deaminate double-stranded DNA or single or DOUBLE-STRANDED RNA. It exhibits potent antiviral activity against VIF PROTEIN deficient HIV-1 through the creation of hypermutations in the VIRAL DNA. It also has anti-viral activity against SIMIAN IMMUNODEFICIENCY VIRUSES and HEPATITIS B VIRUS.
| Descriptor ID |
D000071480
|
| MeSH Number(s) |
D08.811.277.151.486.250.500.750
|
| Concept/Terms |
APOBEC-3G Deaminase- APOBEC-3G Deaminase
- APOBEC 3G Deaminase
- Deaminase, APOBEC-3G
- APOBEC-Related Cytidine Deaminase
- APOBEC Related Cytidine Deaminase
- Cytidine Deaminase, APOBEC-Related
- APOBEC3G Protein
- CEM15 Protein
- APOBEC3G Deaminase
- Deaminase, APOBEC3G
- APOBEC-3G Protein
- APOBEC 3G Protein
- APOBEC-Related Protein
- APOBEC Related Protein
- APOBEC-3G dC-dU Editing Enzyme
- APOBEC 3G dC dU Editing Enzyme
|
Below are MeSH descriptors whose meaning is more general than "APOBEC-3G Deaminase".
Below are MeSH descriptors whose meaning is more specific than "APOBEC-3G Deaminase".
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