DNA-(Apurinic or Apyrimidinic Site) Lyase
"DNA-(Apurinic or Apyrimidinic Site) Lyase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA repair enzyme that catalyses the excision of ribose residues at apurinic and apyrimidinic DNA sites that can result from the action of DNA GLYCOSYLASES. The enzyme catalyzes a beta-elimination reaction in which the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. This enzyme was previously listed under EC 3.1.25.2.
| Descriptor ID |
D043603
|
| MeSH Number(s) |
D08.811.074.750 D08.811.520.241.225
|
| Concept/Terms |
DNA-(Apurinic or Apyrimidinic Site) Lyase- DNA-(Apurinic or Apyrimidinic Site) Lyase
- AP Endonuclease
- Endonuclease, AP
- Endodeoxyribonuclease (Apurinic or Apyrimidinic)
- Apurine-Apyrimidine Endonuclease
- Apurine Apyrimidine Endonuclease
- Endonuclease, Apurine-Apyrimidine
- Apurinic DNA Endonuclease
- DNA Endonuclease, Apurinic
- Endonuclease, Apurinic DNA
- Apurinic Endonuclease
- Endonuclease, Apurinic
- DNA Lyase (Apurinic or Apyrimidinic)
- AP Lyase
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