"MicroRNAs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.
| Descriptor ID |
D035683
|
| MeSH Number(s) |
D13.150.650.319 D13.444.735.150.319 D13.444.735.790.552.500
|
| Concept/Terms |
MicroRNAs- MicroRNAs
- MicroRNA
- miRNAs
- Micro RNA
- RNA, Micro
- miRNA
Primary MicroRNA- Primary MicroRNA
- MicroRNA, Primary
- Primary miRNA
- miRNA, Primary
- pri-miRNA
- pri miRNA
|
Below are MeSH descriptors whose meaning is more general than "MicroRNAs".
Below are MeSH descriptors whose meaning is more specific than "MicroRNAs".
This graph shows the total number of publications written about "MicroRNAs" by people in this website by year, and whether "MicroRNAs" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 5 | 0 | 5 |
| 2018 | 1 | 0 | 1 |
| 2019 | 3 | 0 | 3 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "MicroRNAs" by people in Profiles.
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DNA self-assembled FeNxC nanocatalytic network for ultrasensitive electrochemical detection of microRNA. Anal Chim Acta. 2022 Aug 29; 1223:340218.
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Molecular markers of risk of subsequent invasive breast cancer in women with ductal carcinoma in situ: protocol for a population-based cohort study. BMJ Open. 2021 10 26; 11(10):e053397.
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miRNA contributions to pediatric-onset multiple sclerosis inferred from GWAS. Ann Clin Transl Neurol. 2019 Jun; 6(6):1053-1061.
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Rolling circle amplification-mediated in situ synthesis of palladium nanoparticles for the ultrasensitive electrochemical detection of microRNA. Analyst. 2019 Jun 21; 144(12):3817-3825.
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A miRNA Expression Signature in Breast Tumor Tissue Is Associated with Risk of Distant Metastasis. Cancer Res. 2019 04 01; 79(7):1705-1713.
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Physical activity and epigenetic biomarkers in maternal blood during pregnancy. Epigenomics. 2018 11; 10(11):1383-1395.
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The NF-?B signalling pathway in colorectal cancer: associations between dysregulated gene and miRNA expression. J Cancer Res Clin Oncol. 2018 Feb; 144(2):269-283.
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The PI3K/AKT signaling pathway: Associations of miRNAs with dysregulated gene expression in colorectal cancer. Mol Carcinog. 2018 02; 57(2):243-261.
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The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer. Genes Chromosomes Cancer. 2017 11; 56(11):769-787.
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Genome-wide association screens for Achilles tendon and ACL tears and tendinopathy. PLoS One. 2017; 12(3):e0170422.