Hepatocyte Nuclear Factor 4
"Hepatocyte Nuclear Factor 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subfamily of nuclear receptors that regulate GENETIC TRANSCRIPTION of a diverse group of GENES involved in the synthesis of BLOOD COAGULATION FACTORS; and in GLUCOSE; CHOLESTEROL; and FATTY ACIDS metabolism.
| Descriptor ID |
D051557
|
| MeSH Number(s) |
D12.776.260.262.968 D12.776.660.352.968 D12.776.826.119 D12.776.930.318.968
|
| Concept/Terms |
Hepatocyte Nuclear Factor 4- Hepatocyte Nuclear Factor 4
- Hepatocyte Nuclear Factor-Forkhead Homolog 4
- Hepatocyte Nuclear Factor Forkhead Homolog 4
- HNF4 Transcription Factor
- Transcription Factor, HNF4
|
Below are MeSH descriptors whose meaning is more general than "Hepatocyte Nuclear Factor 4".
Below are MeSH descriptors whose meaning is more specific than "Hepatocyte Nuclear Factor 4".
This graph shows the total number of publications written about "Hepatocyte Nuclear Factor 4" by people in this website by year, and whether "Hepatocyte Nuclear Factor 4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hepatocyte Nuclear Factor 4" by people in Profiles.
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Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer. Nat Commun. 2018 02 08; 9(1):556.
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Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin. Clin Pharmacol Ther. 2014 Sep; 96(3):370-9.
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Prevalence, characteristics and clinical diagnosis of maturity onset diabetes of the young due to mutations in HNF1A, HNF4A, and glucokinase: results from the SEARCH for Diabetes in Youth. J Clin Endocrinol Metab. 2013 Oct; 98(10):4055-62.
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Evidence of interaction between PPARG2 and HNF4A contributing to variation in insulin sensitivity in Mexican Americans. Diabetes. 2008 Apr; 57(4):1048-56.
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Genetics of gestational diabetes mellitus and type 2 diabetes. Diabetes Care. 2007 Jul; 30 Suppl 2:S134-40.