"Genetic Pleiotropy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phenomenon in which multiple and diverse phenotypic outcomes are influenced by a single gene (or single gene product.)
| Descriptor ID |
D058685
|
| MeSH Number(s) |
G05.420.556 G05.695.550
|
| Concept/Terms |
Genetic Pleiotropy- Genetic Pleiotropy
- Pleiotropy, Genetic
- Genetic Pleiotropism
- Pleiotropism, Genetic
Pleiotropic Gene- Pleiotropic Gene
- Gene, Pleiotropic
- Genes, Pleiotropic
- Pleiotropic Genes
|
Below are MeSH descriptors whose meaning is more general than "Genetic Pleiotropy".
Below are MeSH descriptors whose meaning is more specific than "Genetic Pleiotropy".
This graph shows the total number of publications written about "Genetic Pleiotropy" by people in this website by year, and whether "Genetic Pleiotropy" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genetic Pleiotropy" by people in Profiles.
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Large-scale genomic analyses reveal insights into pleiotropy across circulatory system diseases and nervous system disorders. Nat Commun. 2022 Jun 14; 13(1):3428.
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Lossless integration of multiple electronic health records for identifying pleiotropy using summary statistics. Nat Commun. 2021 01 08; 12(1):168.
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Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Nat Commun. 2020 09 04; 11(1):4423.
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Pleiotropic analysis of cancer risk loci on esophageal adenocarcinoma risk. Cancer Epidemiol Biomarkers Prev. 2015 Nov; 24(11):1801-3.
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Cross-cancer pleiotropic analysis of endometrial cancer: PAGE and E2C2 consortia. Carcinogenesis. 2014 Sep; 35(9):2068-73.
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A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects. Hum Genet. 2014 Jan; 133(1):95-109.
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Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia. Gut. 2014 May; 63(5):800-7.