The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.

Descriptor ID	D013974
MeSH Number(s)	D06.472.931.812 D12.125.072.050.767
Concept/Terms	Thyroxine Thyroxine T4 Thyroid Hormone Thyroid Hormone, T4 Thyroxin O-(4-Hydroxy-3,5-diiodophenyl) 3,5-diiodo-L-tyrosine L-3,5,3',5'-Tetraiodothyronine Levothyroxine L-Thyroxine L Thyroxine 3,5,3',5'-Tetraiodothyronine O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine L-Thyroxin Henning L-Thyroxin Henning L Thyroxin Henning LThyroxin Henning Levothyroxine Sodium Levothyroxine Sodium Sodium Levothyroxine Levoxine Levoxine Levoxyl Levoxyl Lévothyrox Lévothyrox L-Thyroxine Roche L-Thyroxine Roche L Thyroxine Roche Levo-T Levo-T Levo T LevoT Levothroid Levothroid Novothyral Novothyral Berlthyrox Berlthyrox Dexnon Dexnon Novothyrox Novothyrox Oroxine Oroxine Synthroid Synthroid Synthrox Synthrox Thyrax Thyrax Tiroidine Tiroidine Tiroxina Leo Tiroxina Leo Leo, Tiroxina Unithroid Unithroid Eferox Eferox Eltroxin Eltroxin Thevier Eltroxine Eltroxine Euthyrox Euthyrox Eutirox L-Thyrox L-Thyrox L Thyrox L-Thyroxin beta L-Thyroxin beta L Thyroxin beta LThyroxin beta Levothyroid Levothyroid Levothyroxin Deladande Levothyroxin Deladande Deladande, Levothyroxin Levothyroxin Delalande Delalande, Levothyroxin

Below are MeSH descriptors whose meaning is more general than "Thyroxine".

Below are MeSH descriptors whose meaning is related to "Thyroxine".

Below are MeSH descriptors whose meaning is more specific than "Thyroxine".