"Polypharmacy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The use of multiple drugs administered to the same patient, most commonly seen in elderly patients. It includes also the administration of excessive medication. Since in the United States most drugs are dispensed as single-agent formulations, polypharmacy, though using many drugs administered to the same patient, must be differentiated from DRUG COMBINATIONS, single preparations containing two or more drugs as a fixed dose, and from DRUG THERAPY, COMBINATION, two or more drugs administered separately for a combined effect. (From Segen, Dictionary of Modern Medicine, 1992)
Descriptor ID |
D019338
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MeSH Number(s) |
E02.319.698
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Polypharmacy".
Below are MeSH descriptors whose meaning is more specific than "Polypharmacy".
This graph shows the total number of publications written about "Polypharmacy" by people in this website by year, and whether "Polypharmacy" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2011 | 1 | 0 | 1 |
2015 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2017 | 0 | 2 | 2 |
2020 | 0 | 1 | 1 |
2021 | 1 | 0 | 1 |
2022 | 0 | 1 | 1 |
2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Polypharmacy" by people in Profiles.
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Willingness of older people living with dementia and mild cognitive impairment and their caregivers to have medications deprescribed. Age Ageing. 2023 01 08; 52(1).
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Deprescribing medications: Do out-of-pocket costs have a role? J Am Geriatr Soc. 2022 11; 70(11):3334-3337.
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Evidence-Based Prescribing and Polypharmacy for Patients With Heart Failure. Ann Intern Med. 2021 08; 174(8):1165-1166.
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The OPTIMIZE patient- and family-centered, primary care-based deprescribing intervention for older adults with dementia or mild cognitive impairment and multiple chronic conditions: study protocol for a pragmatic cluster randomized controlled trial. Trials. 2020 Jun 18; 21(1):542.
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Blood Pressure, Antihypertensive Polypharmacy, Frailty, and Risk for Serious Fall Injuries Among Older Treated Adults With Hypertension. Hypertension. 2017 08; 70(2):259-266.
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Prescriber Continuity and Disease Control of Older Adults. Med Care. 2017 04; 55(4):405-410.
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Changes in Medication Use After Dementia Diagnosis in an Observational Cohort of Individuals with Diabetes Mellitus. J Am Geriatr Soc. 2017 01; 65(1):77-82.
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Medical comorbidity and psychotropic medication fills in older adults with breast or prostate cancer. Support Care Cancer. 2015 Oct; 23(10):3005-9.
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Changes in use of lipid-lowering medications among black and white dual enrollees with diabetes transitioning from Medicaid to Medicare Part D drug coverage. Med Care. 2014 Aug; 52(8):695-703.
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Plasma renin activity (PRA) levels and antihypertensive drug use in a large healthcare system. Am J Hypertens. 2012 Mar; 25(3):379-88.