"Interleukin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation.
    
			
			
				
				
					
						| Descriptor ID | 
										
							D007375
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						| MeSH Number(s) | 
						
							 D12.644.276.374.465.010 D12.644.276.374.500.400 D12.776.467.374.465.010 D12.776.467.374.500.400 D23.529.374.465.131 D23.529.374.500.400 
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						| Concept/Terms | 
						
							Interleukin-1- Interleukin-1
 - Interleukin 1
 - IL-1
 - T Helper Factor
 - Lymphocyte-Activating Factor
 - Lymphocyte Activating Factor
 - Macrophage Cell Factor
 - Epidermal Cell Derived Thymocyte-Activating Factor
 - Epidermal Cell Derived Thymocyte Activating Factor
 - Interleukin I
 
  
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				Below are MeSH descriptors whose meaning is more general than "Interleukin-1".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Interleukin-1".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Interleukin-1" by people in this website by year, and whether "Interleukin-1" was a major or minor topic of these publications. 
				
					
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 2004 | 0 | 1 | 1 | 
| 2016 | 0 | 1 | 1 | 
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				Below are the most recent publications written about "Interleukin-1" by people in Profiles.
						
					
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Inflammation and Progression of CKD: The CRIC Study. Clin J Am Soc Nephrol. 2016 09 07; 11(9):1546-56.
															
								 
							
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Elevated maternal interleukin-8 levels and risk of schizophrenia in adult offspring. Am J Psychiatry. 2004 May; 161(5):889-95.
															
								 
							
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Long-term effects of 60-Hz electric vs. magnetic fields on IL-1 and IL-2 activity in sheep. Bioelectromagnetics. 2001 Apr; 22(3):170-7.