An allosteric enzyme that regulates glycolysis and gluconeogenesis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-2,6-bisphosphate, an allosteric effector for the other 6-phosphofructokinase, PHOSPHOFRUCTOKINASE-1. Phosphofructokinase-2 is bifunctional: the dephosphorylated form is a kinase and the phosphorylated form is a phosphatase that breaks down fructose-2,6-bisphosphate to yield fructose-6-phosphate.

Descriptor ID	D025481
MeSH Number(s)	D08.811.277.352.650.622 D08.811.641.843 D08.811.913.696.620.225.850.750
Concept/Terms	Phosphofructokinase-2 Phosphofructokinase-2 Phosphofructokinase 2 ATP-D-Fructose-6-phosphate 2-phosphotransferase 6-Phosphofructo-2-kinase Fructose-6-P,2-kinase Fructose-6-phosphate,2-kinase 6PF2K Fru-6-P,2-kinase Fructose-2,6-bisphosphatase Fructose-2,6-bisphosphatase Fructose-2,6-bisphosphate 2-phosphatase fructose-2,6-diphosphatase Fructose 2,6-bisphosphatase 6-Phosphofructo-2-kinase-fructose-2,6-bisphosphatase 6-Phosphofructo-2-kinase-fructose-2,6-bisphosphatase 6-Phosphofructo 2-kinase-fructose 2,6-bisphosphatase Fructose-6-phosphate,2-kinase-fructose-2,6-bisphosphatase 6-PF-2-K-Fru-2,6-P(2)ase F Kinase-F-bisphosphatase Fru-kinase-Fru-bisphosphatase

Below are MeSH descriptors whose meaning is more general than "Phosphofructokinase-2".

Below are MeSH descriptors whose meaning is related to "Phosphofructokinase-2".

Below are MeSH descriptors whose meaning is more specific than "Phosphofructokinase-2".