Peroxisomal Multifunctional Protein-2
"Peroxisomal Multifunctional Protein-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dimeric protein found in liver peroxisomes that plays an important role in FATTY ACID metabolism and steroid metabolism. The dimer is formed by cleavage of a single protein precursor and contains an enoyl-CoA hydratase-2 domain and a second domain that displays (S)-3-hydroxyacyl-CoA dehydrogenase and 17-beta-estradiol dehydrogenase activities. The enzyme is stereospecific with regards to arrangement of the substrate double bonds and position of the 3-hydroxy group of the reaction intermediate. It is complemented by PEROXISOMAL BIFUNCTIONAL ENZYME, which has the opposite reaction stereospecificity.
| Descriptor ID |
D064029
|
| MeSH Number(s) |
D08.811.520.241.300.275.500 D08.811.641.812 D08.811.682.047.436.375.640 D08.811.682.047.820.150.926
|
| Concept/Terms |
Peroxisomal Multifunctional Protein-2- Peroxisomal Multifunctional Protein-2
- Multifunctional Protein-2, Peroxisomal
- Peroxisomal Multifunctional Protein 2
- 3-alpha,7-alpha,12-alpha-Trihydroxy-5-beta-Cholest-24-enoyl-CoA Hydratase
- Peroxisomal Multifunctional Enzyme Type 2
- 17-beta-Hydroxysteroid Dehydrogenase 4
- 17 beta Hydroxysteroid Dehydrogenase 4
- 4, 17-beta-Hydroxysteroid Dehydrogenase
- Dehydrogenase 4, 17-beta-Hydroxysteroid
|
Below are MeSH descriptors whose meaning is more general than "Peroxisomal Multifunctional Protein-2".
Below are MeSH descriptors whose meaning is more specific than "Peroxisomal Multifunctional Protein-2".
This graph shows the total number of publications written about "Peroxisomal Multifunctional Protein-2" by people in this website by year, and whether "Peroxisomal Multifunctional Protein-2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Peroxisomal Multifunctional Protein-2" by people in Profiles.
-
Genetic variation in hormone metabolizing genes and risk of testicular germ cell tumors. Cancer Causes Control. 2008 Nov; 19(9):917-29.