"Phosphofructokinase-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. D-tagatose- 6-phosphate and sedoheptulose-7-phosphate also are acceptors. UTP, CTP, and ITP also are donors. In human phosphofructokinase-1, three types of subunits have been identified. They are PHOSPHOFRUCTOKINASE-1, MUSCLE TYPE; PHOSPHOFRUCTOKINASE-1, LIVER TYPE; and PHOSPHOFRUCTOKINASE-1, TYPE C; found in platelets, brain, and other tissues.
| Descriptor ID |
D010732
|
| MeSH Number(s) |
D08.811.913.696.620.225.850.500
|
| Concept/Terms |
Phosphofructokinase-1- Phosphofructokinase-1
- Phosphofructokinase 1
- 6-Phosphofructokinase
- 6 Phosphofructokinase
- Fructose-6-phosphate 1-Phosphotransferase
- 6-Phosphofructo-1-kinase
- Fructose-6-P 1-Kinase
|
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