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William J. Towner, MD, FACP, FIDSA

TitleResearch Scientist III
InstitutionKaiser Permanente Southern California
DepartmentDepartment of Research and Evaluation
Address100 South Los Robles Avenue
Pasadena CA 91101
ORCID ORCID Icon0000-0001-5645-2979 Additional info
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    Other Positions
    TitlePhysician Director, Division of Clinical Trials Research
    InstitutionKaiser Permanente Southern California
    DepartmentDepartment of Research and Evaluation

    TitleAssociate Professor
    InstitutionKaiser Permanente Bernard J. Tyson School of Medicine
    DepartmentClinical Science


    Collapse Overview 
    Collapse overview
    Dr. Towner is interested in the development and execution of pragmatic clinical trials that seek to answer how to best deliver care for a multitude of chronic disease conditions. His current clinical trial research focuses on infectious diseases, particularly HIV and Hepatitis C. He also conduct outcomes research in infectious disease.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lam JO, Leyden WA, Alexeeff S, Lea AN, Hechter RC, Hu H, Marcus JL, Pitts L, Yuan Q, Towner WJ, Horberg MA, Silverberg MJ. Changes in Body Mass Index Over Time in People With and Without HIV Infection. Open Forum Infect Dis. 2024 Feb; 11(2):ofad611. PMID: 38323078; PMCID: PMC10846771.
      Citations:    
    2. Hechter RC, Zhou H, Leyden WA, Yuan Q, Pak KJ, Lam JO, Alexeeff S, Lea A, Hu H, Marcus JL, Rivera AS, Adams AL, Horberg MA, Towner WJ, Lo JC, Silverberg MJ. Fracture Risk and Association With TDF Use Among People With HIV in Large Integrated Health Systems. J Acquir Immune Defic Syndr. 2023 12 01; 94(4):341-348. PMID: 37884055.
      Citations:    
    3. Silverberg MJ, Pimentel N, Leyden WA, Leong TK, Reynolds K, Ambrosy AP, Towner WJ, Hechter RC, Horberg M, Vupputuri S, Harrison TN, Lea AN, Sung SH, Go AS, Neugebauer R. Initial antiretroviral therapy regimen and risk of heart failure. AIDS. 2023 Nov 14. PMID: 37967231.
      Citations:    
    4. Ackerson B, Sy LS, Slezak J, Qian L, Reynolds K, Huang R, Solano Z, Towner W, Qiu S, Simmons SR, Jacobsen SJ, Bruxvoort KJ. Post-licensure safety study of new-onset immune-mediated diseases, herpes zoster, and anaphylaxis in adult recipients of HepB-CpG vaccine versus HepB-alum vaccine. Vaccine. 2023 Jul 05; 41(30):4392-4401. PMID: 37308363.
      Citations:    Fields:    Translation:HumansCells
    5. Piazza G, Spyropoulos AC, Hsia J, Goldin M, Towner WJ, Go AS, Bull TM, Weng S, Lipardi C, Barnathan ES, Bonaca MP, PREVENT-HD Investigators. Rivaroxaban for Prevention of Thrombotic Events, Hospitalization, and Death in Outpatients With COVID-19: A Randomized Clinical Trial. Circulation. 2023 06 20; 147(25):1891-1901. PMID: 37154020; PMCID: PMC10270282.
      Citations:    Fields:    Translation:Humans
    6. Nacht CL, Felner JK, Muthuramalingam S, Towner W, Ling Grant D, Martos A, Chang JM, Hechter R, Storholm ED. Barriers and Opportunities to Improve the Implementation of Patient Screening and Linkage to Pre-Exposure Prophylaxis in Primary Care. J Clin Res HIV AIDS Prev. 2022; 4(2):15-31. PMID: 37841674; PMCID: PMC10572105.
      Citations:    
    7. Lam JO, Leyden WA, Leong TK, Horberg MA, Reynolds K, Ambrosy AP, Avula HR, Hechter RC, Towner WJ, Vupputuri S, Go AS, Silverberg MJ. Variation in Heart Failure Risk by HIV Severity and Sex in People With HIV Infection. J Acquir Immune Defic Syndr. 2022 10 01; 91(2):175-181. PMID: 36094484; PMCID: PMC9471068.
      Citations:    Fields:    Translation:Humans
    8. Mefford MT, Silverberg MJ, Leong TK, Hechter RC, Towner WJ, Go AS, Horberg M, Hu H, Harrison TN, Sung SH, Reynolds K. Multimorbidity Burden and Incident Heart Failure Among People With and Without HIV: The HIV-HEART Study. Mayo Clin Proc Innov Qual Outcomes. 2022 Jun; 6(3):218-227. PMID: 35539894; PMCID: PMC9079699.
      Citations: 2     
    9. Hechter RC, Bruxvoort KJ, Zhou H, Towner WJ, Contreras R, Schumacher CM, Grant DL, Jones J. Sexually transmitted infections among men and transgender women using HIV pre-exposure prophylaxis in a large integrated health system- a cohort study. J Acquir Immune Defic Syndr. 2022 May 02. PMID: 35499561.
      Citations:    Fields:    Translation:HumansPHPublic Health
    10. Bruxvoort K, Slezak J, Qian L, Sy LS, Ackerson B, Reynolds K, Huang R, Solano Z, Towner W, Mercado C, Jacobsen SJ. Association Between 2-Dose vs 3-Dose Hepatitis B Vaccine and Acute Myocardial Infarction. JAMA. 2022 04 05; 327(13):1260-1268. PMID: 35333303; PMCID: PMC8957040.
      Citations: 2     Fields:    Translation:Humans
    11. Lam JO, Lee C, Gilsanz P, Hou CE, Leyden WA, Satre DD, Flamm JA, Towner WJ, Horberg MA, Silverberg MJ. Comparison of dementia incidence and prevalence between individuals with and without HIV infection in primary care from 2000 to 2016. AIDS. 2022 Mar 01; 36(3):437-445. PMID: 34816805.
      Citations: 6     Fields:    Translation:Humans
    12. Go AS, Reynolds K, Avula HR, Towner WJ, Hechter RC, Horberg MA, Vupputuri S, Leong TK, Leyden WA, Harrison TN, Lee KK, Sung SH, Silverberg MJ. Human Immunodeficiency Virus Infection and Variation in Heart Failure Risk by Age, Sex, and Ethnicity: The HIV HEART Study. Mayo Clin Proc. 2021 Dec 11. PMID: 34916054.
      Citations: 3     Fields:    Translation:Humans
    13. Avula HR, Ambrosy AP, Silverberg MJ, Reynolds K, Towner WJ, Hechter RC, Horberg M, Vupputuri S, Leong TK, Leyden WA, Harrison TN, Lee KK, Sung SH, Go AS. Human immunodeficiency virus infection and risks of morbidity and death in adults with incident heart failure. Eur Heart J Open. 2021 Nov; 1(3):oeab040. PMID: 35919879; PMCID: PMC9242035.
      Citations:    
    14. Bruxvoort KJ, Schumacher CM, Towner W, Jones J, Contreras R, Ling Grant D, Hechter RC. Referral Linkage to Preexposure Prophylaxis Care and Persistence on Preexposure Prophylaxis in an Integrated Health Care System. J Acquir Immune Defic Syndr. 2021 Jul 01; 87(3):918-927. PMID: 33633035.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    15. Anderson SJ, Murray M, Cella D, Grossberg R, Hagins D, Towner W, Wang M, Clark A, Pierce A, Llamoso C, Ackerman P, Lataillade M. Patient-Reported Outcomes in the Phase III BRIGHTE Trial of the HIV-1 Attachment Inhibitor Prodrug Fostemsavir in Heavily Treatment-Experienced Individuals. Patient. 2021 Jun 28. PMID: 34180035.
      Citations: 1     Fields:    Translation:HumansCellsCTClinical Trials
    16. Bruxvoort K, Sy LS, Ackerson BK, Slezak J, Qian L, Towner W, Reynolds K, Solano Z, Carlson CM, Jacobsen SJ. Challenges in Phase 4 post-licensure safety studies using real world data in the United States: Hepatitis B vaccine example. Vaccine X. 2021 Aug; 8:100101. PMID: 34195599; PMCID: PMC8233154.
      Citations: 1     
    17. Storholm ED, Siconolfi D, Huang W, Towner W, Grant DL, Martos A, Chang JM, Hechter R. Project SLIP: Implementation of a PrEP Screening and Linkage Intervention in Primary Care. AIDS Behav. 2021 Aug; 25(8):2348-2357. PMID: 33624193.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    18. Bruxvoort K, Slezak J, Huang R, Ackerson B, Sy LS, Qian L, Reynolds K, Towner W, Solano Z, Mercado C, Hyer R, Janssen R, Jacobsen SJ. Association of Number of Doses With Hepatitis B Vaccine Series Completion in US Adults. JAMA Netw Open. 2020 11 02; 3(11):e2027577. PMID: 33252692; PMCID: PMC7705595.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    19. Marcus JL, Leyden WA, Alexeeff SE, Anderson AN, Hechter RC, Hu H, Lam JO, Towner WJ, Yuan Q, Horberg MA, Silverberg MJ. Comparison of Overall and Comorbidity-Free Life Expectancy Between Insured Adults With and Without HIV Infection, 2000-2016. JAMA Netw Open. 2020 06 01; 3(6):e207954. PMID: 32539152; PMCID: PMC7296391.
      Citations: 120     Fields:    Translation:Humans
    20. Goldman JD, Lye DCB, Hui DS, Marks KM, Bruno R, Montejano R, Spinner CD, Galli M, Ahn MY, Nahass RG, Chen YS, SenGupta D, Hyland RH, Osinusi AO, Cao H, Blair C, Wei X, Gaggar A, Brainard DM, Towner WJ, Muñoz J, Mullane KM, Marty FM, Tashima KT, Diaz G, Subramanian A, GS-US-540-5773 Investigators. Remdesivir for 5 or 10 Days in Patients with Severe Covid-19. N Engl J Med. 2020 11 05; 383(19):1827-1837. PMID: 32459919; PMCID: PMC7377062.
      Citations: 598     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    21. Nguyen HQ, Moy ML, Liu IA, Fan VS, Gould MK, Desai SA, Towner WJ, Yuen G, Lee JS, Park SJ, Xiang AH. Effect of Physical Activity Coaching on Acute Care and Survival Among Patients With Chronic Obstructive Pulmonary Disease: A Pragmatic Randomized Clinical Trial. JAMA Netw Open. 2019 08 02; 2(8):e199657. PMID: 31418811; PMCID: PMC6704745.
      Citations: 3     Fields:    Translation:Humans
    22. Horberg MA, Oakes AH, Hurley LB, Towner WJ, Chao CR, Silverberg MJ, Chantra JQ, Ellis CG, Quesenberry CP. Association of raltegravir use with long-term health outcomes in HIV-infected patients: an observational post-licensure safety study in a large integrated healthcare system. HIV Clin Trials. 2018 10; 19(5):177-187. PMID: 30370835.
      Citations: 5     Fields:    Translation:Humans
    23. Hechter RC, Bider-Canfield Z, Towner W. Effect of an Electronic Alert on Targeted HIV Testing Among High-Risk Populations. Perm J. 2018; 22:18-015. PMID: 30285916.
      Citations: 1     Fields:    Translation:Humans
    24. Arribas JR, DeJesus E, van Lunzen J, Zurawski C, Doroana M, Towner W, Lazzarin A, Nelson M, McColl D, Andreatta K, Swamy R, Szwarcberg J, Nguyen T. Simplification to single-tablet regimen of elvitegravir, cobicistat, emtricitabine, tenofovir DF from multi-tablet ritonavir-boosted protease inhibitor plus coformulated emtricitabine and tenofovir DF regimens: week 96 results of STRATEGY-PI. HIV Clin Trials. 2017 05; 18(3):118-125. PMID: 28555519.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    25. Marcus JL, Leyden WA, Chao CR, Horberg MA, Klein DB, Quesenberry CP, Towner WJ, Silverberg MJ. Immunodeficiency, AIDS-related pneumonia, and risk of lung cancer among HIV-infected individuals. AIDS. 2017 04 24; 31(7):989-993. PMID: 28252529.
      Citations: 14     Fields:    Translation:Humans
    26. Wu JJ, Gilbert KE, Batech M, Manalo IF, Towner WJ, Raposo RA, Nixon DF, Liao W. Examining HIV Viral Load in a Matched Cohort of HIV Positive Individuals With and Without Psoriasis. J Drugs Dermatol. 2017 Apr 01; 16(4):372-377. PMID: 28403272.
      Citations:    Fields:    Translation:HumansCells
    27. Marcus JL, Baxter R, Leyden WA, Muthulingam D, Yee A, Horberg MA, Klein DB, Towner WJ, Chao CR, Quesenberry CP, Silverberg MJ. Invasive Pneumococcal Disease Among HIV-Infected and HIV-Uninfected Adults in a Large Integrated Healthcare System. AIDS Patient Care STDS. 2016 10; 30(10):463-470. PMID: 27749111.
      Citations: 8     Fields:    Translation:HumansCellsPHPublic Health
    28. Marcus JL, Chao CR, Leyden WA, Xu L, Quesenberry CP, Klein DB, Towner WJ, Horberg MA, Silverberg MJ. Narrowing the Gap in Life Expectancy Between HIV-Infected and HIV-Uninfected Individuals With Access to Care. J Acquir Immune Defic Syndr. 2016 09 01; 73(1):39-46. PMID: 27028501.
      Citations: 177     Fields:    Translation:Humans
    29. Marcus JL, Neugebauer RS, Leyden WA, Chao CR, Xu L, Quesenberry CP, Klein DB, Towner WJ, Horberg MA, Silverberg MJ. Use of Abacavir and Risk of Cardiovascular Disease Among HIV-Infected Individuals. J Acquir Immune Defic Syndr. 2016 Apr 01; 71(4):413-9. PMID: 26536316.
      Citations: 31     Fields:    Translation:Humans
    30. Foster GR, Afdhal N, Roberts SK, Bräu N, Gane EJ, Pianko S, Lawitz E, Thompson A, Shiffman ML, Cooper C, Towner WJ, Conway B, Ruane P, Bourlière M, Asselah T, Berg T, Zeuzem S, Rosenberg W, Agarwal K, Stedman CA, Mo H, Dvory-Sobol H, Han L, Wang J, McNally J, Osinusi A, Brainard DM, McHutchison JG, Mazzotta F, Tran TT, Gordon SC, Patel K, Reau N, Mangia A, Sulkowski M. Sofosbuvir and Velpatasvir for HCV Genotype 2 and 3 Infection. N Engl J Med. 2015 Dec 31; 373(27):2608-17. PMID: 26575258.
      Citations: 256     Fields:    Translation:HumansCellsCTClinical Trials
    31. Feld JJ, Jacobson IM, Hézode C, Asselah T, Ruane PJ, Gruener N, Abergel A, Mangia A, Lai CL, Chan HL, Mazzotta F, Moreno C, Yoshida E, Shafran SD, Towner WJ, Tran TT, McNally J, Osinusi A, Svarovskaia E, Zhu Y, Brainard DM, McHutchison JG, Agarwal K, Zeuzem S. Sofosbuvir and Velpatasvir for HCV Genotype 1, 2, 4, 5, and 6 Infection. N Engl J Med. 2015 Dec 31; 373(27):2599-607. PMID: 26571066.
      Citations: 356     Fields:    Translation:HumansCellsCTClinical Trials
    32. Everson GT, Towner WJ, Davis MN, Wyles DL, Nahass RG, Thuluvath PJ, Etzkorn K, Hinestrosa F, Tong M, Rabinovitz M, McNally J, Brainard DM, Han L, Doehle B, McHutchison JG, Morgan T, Chung RT, Tran TT. Sofosbuvir With Velpatasvir in Treatment-Naive Noncirrhotic Patients With Genotype 1 to 6 Hepatitis C Virus Infection: A Randomized Trial. Ann Intern Med. 2015 Dec 01; 163(11):818-26. PMID: 26551051.
      Citations: 37     Fields:    Translation:HumansCells
    33. Pianko S, Flamm SL, Shiffman ML, Kumar S, Strasser SI, Dore GJ, McNally J, Brainard DM, Han L, Doehle B, Mogalian E, McHutchison JG, Rabinovitz M, Towner WJ, Gane EJ, Stedman CA, Reddy KR, Roberts SK. Sofosbuvir Plus Velpatasvir Combination Therapy for Treatment-Experienced Patients With Genotype 1 or 3 Hepatitis C Virus Infection: A Randomized Trial. Ann Intern Med. 2015 Dec 01; 163(11):809-17. PMID: 26551263.
      Citations: 36     Fields:    Translation:HumansCellsCTClinical Trials
    34. Horberg MA, Hurley LB, Klein DB, Towner WJ, Kadlecik P, Antoniskis D, Mogyoros M, Brachman PS, Remmers CL, Gambatese RC, Blank J, Ellis CG, Silverberg MJ. The HIV Care Cascade Measured Over Time and by Age, Sex, and Race in a Large National Integrated Care System. AIDS Patient Care STDS. 2015 Nov; 29(11):582-90. PMID: 26505968.
      Citations: 55     Fields:    Translation:Humans
    35. Nguyen HQ, Bailey A, Coleman KJ, Desai S, Fan VS, Gould MK, Maddock L, Miller K, Towner W, Xiang AH, Moy ML. Patient-centered physical activity coaching in COPD (Walk On!): A study protocol for a pragmatic randomized controlled trial. Contemp Clin Trials. 2016 Jan; 46:18-29. PMID: 26597414.
      Citations: 10     Fields:    Translation:Humans
    36. Naggie S, Cooper C, Saag M, Workowski K, Ruane P, Towner WJ, Marks K, Luetkemeyer A, Baden RP, Sax PE, Gane E, Santana-Bagur J, Stamm LM, Yang JC, German P, Dvory-Sobol H, Ni L, Pang PS, McHutchison JG, Stedman CA, Morales-Ramirez JO, Bräu N, Jayaweera D, Colson AE, Tebas P, Wong DK, Dieterich D, Sulkowski M. Ledipasvir and Sofosbuvir for HCV in Patients Coinfected with HIV-1. N Engl J Med. 2015 Aug 20; 373(8):705-13. PMID: 26196665.
      Citations: 183     Fields:    Translation:HumansCellsCTClinical Trials
    37. Marcus JL, Leyden WA, Chao CR, Xu L, Quesenberry CP, Tien PC, Klein DB, Towner WJ, Horberg MA, Silverberg MJ. Differences in Response to Antiretroviral Therapy by Sex and Hepatitis C Infection Status. AIDS Patient Care STDS. 2015 Jul; 29(7):370-8. PMID: 26061798.
      Citations: 16     Fields:    Translation:HumansCells
    38. Marcus JL, Chao C, Leyden WA, Xu L, Yu J, Horberg MA, Klein D, Towner WJ, Quesenberry CP, Abrams DI, Silverberg MJ. Survival among HIV-infected and HIV-uninfected individuals with common non-AIDS-defining cancers. Cancer Epidemiol Biomarkers Prev. 2015 Aug; 24(8):1167-73. PMID: 25713023.
      Citations: 44     Fields:    Translation:Humans
    39. Klein DB, Leyden WA, Xu L, Chao CR, Horberg MA, Towner WJ, Hurley LB, Marcus JL, Quesenberry CP, Silverberg MJ. Declining relative risk for myocardial infarction among HIV-positive compared with HIV-negative individuals with access to care. Clin Infect Dis. 2015 Apr 15; 60(8):1278-80. PMID: 25595743.
      Citations: 61     Fields:    Translation:HumansCTClinical Trials
    40. Gazzard B, Girard PM, Di Perri G, Gallant J, Towner W, Rogatto F, Demorin J, McColl D, Liu H, Rhee M, Szwarcberg J, Piontkowsky D. Long-term efficacy and safety of E/C/F/TDF vs EFV/FTC/TDF and ATV+RTV+FTC/TDF in HIV-1-infected treatment-naïve subjects =50 years. J Int AIDS Soc. 2014; 17(4 Suppl 3):19767. PMID: 25397511.
      Citations: 2     Fields:    
    41. Marcus JL, Leyden WA, Chao CR, Chow FC, Horberg MA, Hurley LB, Klein DB, Quesenberry CP, Towner WJ, Silverberg MJ. HIV infection and incidence of ischemic stroke. AIDS. 2014 Aug 24; 28(13):1911-9. PMID: 24937309.
      Citations: 69     Fields:    Translation:Humans
    42. Marcus JL, Chao CR, Leyden WA, Xu L, Klein DB, Horberg MA, Towner WJ, Quesenberry CP, Abrams DI, Van Den Eeden SK, Silverberg MJ. Prostate cancer incidence and prostate-specific antigen testing among HIV-positive and HIV-negative men. J Acquir Immune Defic Syndr. 2014 Aug 15; 66(5):495-502. PMID: 24820107.
      Citations: 21     Fields:    Translation:Humans
    43. Manns M, Pol S, Jacobson IM, Marcellin P, Gordon SC, Peng CY, Chang TT, Everson GT, Heo J, Gerken G, Yoffe B, Towner WJ, Bourliere M, Metivier S, Chu CJ, Sievert W, Bronowicki JP, Thabut D, Lee YJ, Kao JH, McPhee F, Kopit J, Mendez P, Linaberry M, Hughes E, Noviello S. All-oral daclatasvir plus asunaprevir for hepatitis C virus genotype 1b: a multinational, phase 3, multicohort study. Lancet. 2014 Nov 01; 384(9954):1597-605. PMID: 25078304.
      Citations: 134     Fields:    Translation:HumansCellsCTClinical Trials
    44. Cohen C, Wohl D, Arribas JR, Henry K, Van Lunzen J, Bloch M, Towner W, Wilkins E, Ebrahimi R, Porter D, White K, Walker I, Chuck S, De-Oertel S, Fralich T. Week 48 results from a randomized clinical trial of rilpivirine/emtricitabine/tenofovir disoproxil fumarate vs. efavirenz/emtricitabine/tenofovir disoproxil fumarate in treatment-naive HIV-1-infected adults. AIDS. 2014 Apr 24; 28(7):989-97. PMID: 24508782.
      Citations: 42     Fields:    Translation:HumansCellsCTClinical Trials
    45. Mills A, Crofoot G, Ortiz R, Rashbaum B, Towner W, Ward D, Brinson C, Kulkarni R, Garner W, Ebrahimi R, Cao H, Cheng A, Szwarcberg J. Switching from twice-daily raltegravir plus tenofovir disoproxil fumarate/emtricitabine to once-daily elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate in virologically suppressed, HIV-1-infected subjects: 48 weeks data. HIV Clin Trials. 2014 Mar-Apr; 15(2):51-6. PMID: 24710918.
      Citations: 7     Fields:    Translation:HumansCellsCTClinical Trials
    46. Hechter RC, Jacobsen SJ, Luo Y, Nomura JH, Towner WJ, Tartof SY, Tseng HF. Hepatitis B testing and vaccination among adults with sexually transmitted infections in a large managed care organization. Clin Infect Dis. 2014 Jun; 58(12):1739-45. PMID: 24571863.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    47. Silverberg MJ, Leyden WA, Xu L, Horberg MA, Chao CR, Towner WJ, Hurley LB, Quesenberry CP, Klein DB. Immunodeficiency and risk of myocardial infarction among HIV-positive individuals with access to care. J Acquir Immune Defic Syndr. 2014 Feb 01; 65(2):160-6. PMID: 24442222.
      Citations: 88     Fields:    Translation:Humans
    48. Melikian GL, Rhee SY, Varghese V, Porter D, White K, Taylor J, Towner W, Troia P, Burack J, Dejesus E, Robbins GK, Razzeca K, Kagan R, Liu TF, Fessel WJ, Israelski D, Shafer RW. Non-nucleoside reverse transcriptase inhibitor (NNRTI) cross-resistance: implications for preclinical evaluation of novel NNRTIs and clinical genotypic resistance testing. J Antimicrob Chemother. 2014 Jan; 69(1):12-20. PMID: 23934770.
      Citations: 41     Fields:    Translation:HumansCells
    49. Chao C, Leyden WA, Xu L, Horberg MA, Klein D, Towner WJ, Quesenberry CP, Abrams DI, Silverberg MJ. Exposure to antiretroviral therapy and risk of cancer in HIV-infected persons. AIDS. 2012 Nov 13; 26(17):2223-31. PMID: 22951631.
      Citations: 27     Fields:    Translation:HumansCells
    50. Horberg MA, Hurley LB, Towner WJ, Allerton MW, Tang BT, Catz SL, Silverberg MJ, Quesenberry CP. Influence of provider experience on antiretroviral adherence and viral suppression. HIV AIDS (Auckl). 2012; 4:125-33. PMID: 22924015.
      Citations: 4     
    51. Towner WJ, Xu L, Leyden WA, Horberg MA, Chao CR, Tang B, Klein DB, Hurley LB, Quesenberry CP, Silverberg MJ. The effect of HIV infection, immunodeficiency, and antiretroviral therapy on the risk of hepatic dysfunction. J Acquir Immune Defic Syndr. 2012 Jul 01; 60(3):321-7. PMID: 22343179.
      Citations: 20     Fields:    Translation:HumansCells
    52. Horberg MA, Hurley LB, Towner WJ, Allerton MW, Tang BT, Catz SL, Silverberg MJ, Quesenberry CP. Determination of optimized multidisciplinary care team for maximal antiretroviral therapy adherence. J Acquir Immune Defic Syndr. 2012 Jun 01; 60(2):183-90. PMID: 22293551.
      Citations: 26     Fields:    Translation:Humans
    53. Rhee SY, Blanco JL, Liu TF, Pere I, Kaiser R, Zazzi M, Incardona F, Towner W, Gatell JM, De Luca A, Fessel WJ, Shafer RW. Standardized representation, visualization and searchable repository of antiretroviral treatment-change episodes. AIDS Res Ther. 2012 May 03; 9(1):13. PMID: 22554313.
      Citations: 2     Fields:    
    54. Chao C, Tang B, Hurley L, Silverberg MJ, Towner W, Preciado M, Horberg M. Risk factors for short-term virologic outcomes among HIV-infected patients undergoing regimen switch of combination antiretroviral therapy. AIDS Res Hum Retroviruses. 2012 Dec; 28(12):1630-6. PMID: 22475276.
      Citations: 6     Fields:    Translation:Humans
    55. Chao C, Tang B, Towner W, Silverberg MJ, Hurley L, Horberg M. Short-term clinical outcomes among treatment-experienced HIV-positive patients with early low level viremia. AIDS Patient Care STDS. 2012 May; 26(5):253-5. PMID: 22424146.
      Citations: 3     Fields:    Translation:Humans
    56. Melikian GL, Rhee SY, Taylor J, Fessel WJ, Kaufman D, Towner W, Troia-Cancio PV, Zolopa A, Robbins GK, Kagan R, Israelski D, Shafer RW. Standardized comparison of the relative impacts of HIV-1 reverse transcriptase (RT) mutations on nucleoside RT inhibitor susceptibility. Antimicrob Agents Chemother. 2012 May; 56(5):2305-13. PMID: 22330916.
      Citations: 38     Fields:    Translation:HumansCells
    57. Silverberg MJ, Chao C, Leyden WA, Xu L, Horberg MA, Klein D, Towner WJ, Dubrow R, Quesenberry CP, Neugebauer RS, Abrams DI. HIV infection, immunodeficiency, viral replication, and the risk of cancer. Cancer Epidemiol Biomarkers Prev. 2011 Dec; 20(12):2551-9. PMID: 22109347.
      Citations: 122     Fields:    Translation:Humans
    58. Chao C, Xu L, Abrams DI, Towner WJ, Horberg MA, Leyden WA, Silverberg MJ. HMG-CoA reductase inhibitors (statins) use and risk of non-Hodgkin lymphoma in HIV-positive persons. AIDS. 2011 Sep 10; 25(14):1771-7. PMID: 21681055.
      Citations: 22     Fields:    Translation:Humans
    59. Wohl AR, Carlos JA, Tejero J, Dierst-Davies R, Daar ES, Khanlou H, Cadden J, Towner W, Frye D. Barriers and unmet need for supportive services for HIV patients in care in Los Angeles County, California. AIDS Patient Care STDS. 2011 Sep; 25(9):525-32. PMID: 21774689.
      Citations: 18     Fields:    Translation:Humans
    60. Horberg M, Hurley L, Towner W, Gambatese R, Klein D, Antoniskis D, Weinberg W, Kadlecik P, Remmers C, Dobrinich R, Quesenberry C, Silverberg M, Johnson M. HIV quality performance measures in a large integrated health care system. AIDS Patient Care STDS. 2011 Jan; 25(1):21-8. PMID: 21214376.
      Citations: 14     Fields:    Translation:Humans
    61. Rhee SY, Taylor J, Fessel WJ, Kaufman D, Towner W, Troia P, Ruane P, Hellinger J, Shirvani V, Zolopa A, Shafer RW. HIV-1 protease mutations and protease inhibitor cross-resistance. Antimicrob Agents Chemother. 2010 Oct; 54(10):4253-61. PMID: 20660676.
      Citations: 87     Fields:    Translation:Cells
    62. Chao C, Xu L, Abrams D, Leyden W, Horberg M, Towner W, Klein D, Tang B, Silverberg M. Survival of non-Hodgkin lymphoma patients with and without HIV infection in the era of combined antiretroviral therapy. AIDS. 2010 Jul 17; 24(11):1765-70. PMID: 20453630.
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    63. Grinsztejn B, Di Perri G, Towner W, Woodfall B, De Smedt G, Peeters M. A review of the safety and tolerability profile of the next-generation NNRTI etravirine. AIDS Res Hum Retroviruses. 2010 Jul; 26(7):725-33. PMID: 20624073.
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    64. Towner W, Lalezari J, Sension MG, Wohlfeiler M, Gathe J, Appelbaum JS, Bellman P, Gottlieb MS, Ryan R, Nijs S, Hoogstoel A, Van Solingen-Ristea R, Witek J. Efficacy, safety, and tolerability of etravirine with and without darunavir/ritonavir or raltegravir in treatment-experienced patients: analysis of the etravirine early access program in the United States. J Acquir Immune Defic Syndr. 2010 Apr; 53(5):614-8. PMID: 20134329.
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    65. Horberg M, Tang B, Towner W, Silverberg M, Bersoff-Matcha S, Hurley L, Chang J, Blank J, Quesenberry C, Klein D. Impact of tenofovir on renal function in HIV-infected, antiretroviral-naive patients. J Acquir Immune Defic Syndr. 2010 Jan; 53(1):62-9. PMID: 19838127.
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    66. Towner WJ, Cassetti I, Domingo P, Nijs S, Kakuda TN, Vingerhoets J, Woodfall B. Etravirine: clinical review of a treatment option for HIV type-1-infected patients with non-nucleoside reverse transcriptase inhibitor resistance. Antivir Ther. 2010; 15(6):803-16. PMID: 20834093.
      Citations: 2     Fields:    Translation:HumansCells
    67. Katlama C, Clotet B, Mills A, Trottier B, Molina JM, Grinsztejn B, Towner W, Haubrich R, Nijs S, Vingerhoets J, Woodfall B, Witek J. Efficacy and safety of etravirine at week 96 in treatment-experienced HIV type-1-infected patients in the DUET-1 and DUET-2 trials. Antivir Ther. 2010; 15(7):1045-52. PMID: 21041921.
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    68. Silverberg MJ, Chao C, Leyden WA, Xu L, Tang B, Horberg MA, Klein D, Quesenberry CP, Towner WJ, Abrams DI. HIV infection and the risk of cancers with and without a known infectious cause. AIDS. 2009 Nov 13; 23(17):2337-45. PMID: 19741479.
      Citations: 148     Fields:    Translation:Humans
    69. Shahriar R, Rhee SY, Liu TF, Fessel WJ, Scarsella A, Towner W, Holmes SP, Zolopa AR, Shafer RW. Nonpolymorphic human immunodeficiency virus type 1 protease and reverse transcriptase treatment-selected mutations. Antimicrob Agents Chemother. 2009 Nov; 53(11):4869-78. PMID: 19721070.
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    70. Towner W, Klein D, Kerrigan HL, Follansbee S, Yu K, Horberg M. Virologic outcomes of changing enfuvirtide to raltegravir in HIV-1 patients well controlled on an enfuvirtide based regimen: 24-week results of the CHEER study. J Acquir Immune Defic Syndr. 2009 Aug 01; 51(4):367-73. PMID: 19487951.
      Citations: 10     Fields:    Translation:HumansCellsCTClinical Trials
    71. Horberg M, Klein D, Hurley L, Silverberg M, Towner W, Antoniskis D, Kovach D, Mogyoros M, Blake W, Dobrinich R, Dodge W. Efficacy and safety of ritonavir-boosted and unboosted atazanavir among antiretroviral-naïve patients. HIV Clin Trials. 2008 Nov-Dec; 9(6):367-74. PMID: 19203902.
      Citations: 7     Fields:    Translation:HumansCellsCTClinical Trials
    72. Lawrence JM, Liu IL, Towner WJ. Trends and correlates of HIV testing during pregnancy in racially/ethnically diverse insured population, 1997-2006. Matern Child Health J. 2009 Sep; 13(5):633-40. PMID: 18712463.
      Citations: 3     Fields:    Translation:Humans
    73. Elion R, Dejesus E, Sension M, Berger D, Towner W, Richmond G, St Clair M, Yau L, Ha B. Once-daily abacavir/lamivudine and ritonavir-boosted atazanavir for the treatment of HIV-1 infection in antiretroviral-naïve patients: a 48-week pilot study. HIV Clin Trials. 2008 May-Jun; 9(3):152-63. PMID: 18547902.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    74. Horberg MA, Silverberg MJ, Hurley LB, Towner WJ, Klein DB, Bersoff-Matcha S, Weinberg WG, Antoniskis D, Mogyoros M, Dodge WT, Dobrinich R, Quesenberry CP, Kovach DA. Effects of depression and selective serotonin reuptake inhibitor use on adherence to highly active antiretroviral therapy and on clinical outcomes in HIV-infected patients. J Acquir Immune Defic Syndr. 2008 Mar 01; 47(3):384-90. PMID: 18091609.
      Citations: 128     Fields:    Translation:HumansCells
    75. Towner WJ. The Changing Face of HIV Infection. Perm J. 2008; 12(4):60-4. PMID: 21339926.
      Citations: 2     Fields:    
    76. Lazzarin A, Campbell T, Clotet B, Johnson M, Katlama C, Moll A, Towner W, Trottier B, Peeters M, Vingerhoets J, de Smedt G, Baeten B, Beets G, Sinha R, Woodfall B. Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-2: 24-week results from a randomised, double-blind, placebo-controlled trial. Lancet. 2007 Jul 07; 370(9581):39-48. PMID: 17617271.
      Citations: 115     Fields:    Translation:HumansCells
    77. Horberg M, Antoniskis D, Bersoff-Matcha S, Hurley L, Klein D, Kovach D, Mogyoros M, Towner W, Weinberg W. Perceptions of human immunodeficiency virus testing services among HIV-positive persons not in medical care. Sex Transm Dis. 2006 Jul; 33(7):464; author reply 465. PMID: 16688101.
      Citations:    Fields:    Translation:Humans
    78. Wohl AR, Lu S, Turner J, Kovacs A, Witt M, Squires K, Towner W, Beer V. Risk of opportunistic infection in the HAART era among HIV-infected Latinos born in the United States compared to Latinos born in Mexico and Central America. AIDS Patient Care STDS. 2003 Jun; 17(6):267-75. PMID: 12880490.
      Citations: 7     Fields:    Translation:Humans
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