"Epistasis, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of gene interaction whereby the expression of one gene interferes with or masks the expression of a different gene or genes. Genes whose expression interferes with or masks the effects of other genes are said to be epistatic to the effected genes. Genes whose expression is affected (blocked or masked) are hypostatic to the interfering genes.
Descriptor ID |
D004843
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MeSH Number(s) |
G05.308.207
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Concept/Terms |
Epistasis, Genetic- Epistasis, Genetic
- Epistases, Genetic
- Gene-Gene Interactions, Epistatic
- Gene Gene Interactions, Epistatic
- Gene-Gene Interaction, Epistatic
- Epistatic Gene-Gene Interaction
- Epistatic Gene-Gene Interactions
- Gene Gene Interaction, Epistatic
- Interaction, Epistatic Gene-Gene
- Interactions, Epistatic Gene-Gene
- Non-Allelic Gene Interactions
- Gene Interaction, Non-Allelic
- Gene Interactions, Non-Allelic
- Interaction, Non-Allelic Gene
- Interactions, Non-Allelic Gene
- Non Allelic Gene Interactions
- Non-Allelic Gene Interaction
- Genetic Epistasis
- Genetic Epistases
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Below are MeSH descriptors whose meaning is more general than "Epistasis, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Epistasis, Genetic".
This graph shows the total number of publications written about "Epistasis, Genetic" by people in this website by year, and whether "Epistasis, Genetic" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2010 | 1 | 0 | 1 |
2011 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Epistasis, Genetic" by people in Profiles.
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Identifying gene-gene interactions that are highly associated with four quantitative lipid traits across multiple cohorts. Hum Genet. 2017 02; 136(2):165-178.
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Genome-wide search for gene-gene interactions in colorectal cancer. PLoS One. 2012; 7(12):e52535.
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Computational analysis of simulated SNP interactions between 26 growth factor-related genes in a breast cancer association study. OMICS. 2011 Jun; 15(6):399-407.
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An "almost exhaustive" search-based sequential permutation method for detecting epistasis in disease association studies. Genet Epidemiol. 2010 Jul; 34(5):434-43.
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A second locus for very-late-onset Alzheimer disease: a genome scan reveals linkage to 20p and epistasis between 20p and the amyloid precursor protein region. Am J Hum Genet. 2002 Jul; 71(1):154-61.