"Drug Tolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from DRUG RESISTANCE wherein an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. It should also be differentiated from MAXIMUM TOLERATED DOSE and NO-OBSERVED-ADVERSE-EFFECT LEVEL.
| Descriptor ID |
D004361
|
| MeSH Number(s) |
G07.690.773.992
|
| Concept/Terms |
Drug Tolerance- Drug Tolerance
- Drug Tolerances
- Tolerance, Drug
- Tolerances, Drug
|
Below are MeSH descriptors whose meaning is more general than "Drug Tolerance".
Below are MeSH descriptors whose meaning is more specific than "Drug Tolerance".
This graph shows the total number of publications written about "Drug Tolerance" by people in this website by year, and whether "Drug Tolerance" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Drug Tolerance" by people in Profiles.
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The tolerability of linezolid in the treatment of nontuberculous mycobacterial disease. Eur Respir J. 2015 Apr; 45(4):1177-9.
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Opioid pharmacotherapy for chronic non-cancer pain in the United States: a research guideline for developing an evidence-base. J Pain. 2010 Sep; 11(9):807-29.
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Do heavy smokers benefit from higher dose nicotine patch therapy? Exp Clin Psychopharmacol. 1999 Aug; 7(3):226-33.
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Craving is associated with smoking relapse: findings from three prospective studies. Exp Clin Psychopharmacol. 1997 May; 5(2):137-42.