"Hydrochlorothiazide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
| Descriptor ID |
D006852
|
| MeSH Number(s) |
D02.886.590.700.135.261.476 D02.886.655.500.261.476 D03.633.100.174.261.476
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Hydrochlorothiazide".
Below are MeSH descriptors whose meaning is more specific than "Hydrochlorothiazide".
This graph shows the total number of publications written about "Hydrochlorothiazide" by people in this website by year, and whether "Hydrochlorothiazide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hydrochlorothiazide" by people in Profiles.
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Hydrochlorothiazide use is strongly associated with risk of lip cancer. J Intern Med. 2017 10; 282(4):322-331.
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Automated Outreach for Cardiovascular-Related Medication Refill Reminders. J Clin Hypertens (Greenwich). 2016 07; 18(7):641-6.
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Antihypertensive drugs and lip cancer in non-Hispanic whites. Arch Intern Med. 2012 Sep 10; 172(16):1246-51.
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Medication adherence before an increase in antihypertensive therapy: a cohort study using pharmacy claims data. Clin Ther. 2005 Jun; 27(6):773-81.
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Effect of low-dose thiazide diuretics on plasma lipids: results from a double-blind, randomized clinical trial in older men and women. J Am Geriatr Soc. 2003 Mar; 51(3):340-7.
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Renal cell carcinoma and thiazide use: a historical, case-control study (California, USA). Cancer Causes Control. 1994 Jul; 5(4):319-25.