"Monoamine Oxidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the oxidative deamination of naturally occurring monoamines. It is a flavin-containing enzyme that is localized in mitochondrial membranes, whether in nerve terminals, the liver, or other organs. Monoamine oxidase is important in regulating the metabolic degradation of catecholamines and serotonin in neural or target tissues. Hepatic monoamine oxidase has a crucial defensive role in inactivating circulating monoamines or those, such as tyramine, that originate in the gut and are absorbed into the portal circulation. (From Goodman and Gilman's, The Pharmacological Basis of Therapeutics, 8th ed, p415) EC 1.4.3.4.
Descriptor ID |
D008995
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MeSH Number(s) |
D08.811.682.664.750
|
Concept/Terms |
Monoamine Oxidase- Monoamine Oxidase
- Oxidase, Monoamine
- Amine Oxidase (Flavin-Containing)
- MAO
- Tyramine Oxidase
- Oxidase, Tyramine
|
Below are MeSH descriptors whose meaning is more general than "Monoamine Oxidase".
Below are MeSH descriptors whose meaning is more specific than "Monoamine Oxidase".
This graph shows the total number of publications written about "Monoamine Oxidase" by people in this website by year, and whether "Monoamine Oxidase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 1 | 0 | 1 |
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Below are the most recent publications written about "Monoamine Oxidase" by people in Profiles.
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Relationships between effects of smoking, gender, and alcohol dependence on platelet monoamine oxidase-B: activity, affinity labeling, and protein measurements. Alcohol Clin Exp Res. 2002 Jul; 26(7):1105-13.