A glycoprotein that is central in both the classical and the alternative pathway of COMPLEMENT ACTIVATION. C3 can be cleaved into COMPLEMENT C3A and COMPLEMENT C3B, spontaneously at low level or by C3 CONVERTASE at high level. The smaller fragment C3a is an ANAPHYLATOXIN and mediator of local inflammatory process. The larger fragment C3b binds with C3 convertase to form C5 convertase.

Descriptor ID	D003176
MeSH Number(s)	D12.776.124.050.140 D12.776.124.486.274.250
Concept/Terms	Complement C3 Complement C3 C3, Complement Complement 3 Complement Component 3 Component 3, Complement C3 Complement Complement, C3 Complement C3 Precursor Complement C3 Precursor C3 Precursor, Complement Precursor, Complement C3 Pro-C3 Pro C3 Precursor-Complement 3 Precursor Complement 3 Pro-Complement 3 Pro Complement 3 C3 Precursor Precursor, C3

Below are MeSH descriptors whose meaning is more general than "Complement C3".

Below are MeSH descriptors whose meaning is related to "Complement C3".

Below are MeSH descriptors whose meaning is more specific than "Complement C3".