Heparin-binding EGF-like Growth Factor
"Heparin-binding EGF-like Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An EGF family member that is expressed in a variety of hematopoietic, endothelial, vascular smooth muscle, and epithelial cells. It is synthesized as a transmembrane protein which is cleaved by proteases to produce the secreted form of the protein which has specificity for the EGF RECEPTOR and the ERBB-4 RECEPTOR. The membrane-bound form of the protein has been identified as the receptor which binds to and allows DIPHTHERIA TOXIN to enter cells.
| Descriptor ID |
D066257
|
| MeSH Number(s) |
D12.644.276.382.625 D12.776.467.382.625 D23.529.382.625
|
| Concept/Terms |
Short Form HB-EGF- Short Form HB-EGF
- HB-EGF, Short Form
- Short Form HB EGF
- SF HB-EGF
- SF HB EGF
Heparin-binding Epidermal Growth Factor-like Growth Factor Precursor Protein- Heparin-binding Epidermal Growth Factor-like Growth Factor Precursor Protein
- Heparin binding Epidermal Growth Factor like Growth Factor Precursor Protein
- Receptor, Diphtheria Toxin
- HB-EGF Precursor
- HB EGF Precursor
- Diphtheria Toxin Receptor
- Toxin Receptor, Diphtheria
- Diphtheria Toxin Receptors
- Receptors, Diphtheria Toxin
- Toxin Receptors, Diphtheria
|
Below are MeSH descriptors whose meaning is more general than "Heparin-binding EGF-like Growth Factor".
Below are MeSH descriptors whose meaning is more specific than "Heparin-binding EGF-like Growth Factor".
This graph shows the total number of publications written about "Heparin-binding EGF-like Growth Factor" by people in this website by year, and whether "Heparin-binding EGF-like Growth Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Heparin-binding EGF-like Growth Factor" by people in Profiles.
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Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimers Dement. 2017 Jul; 13(7):727-738.
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Serous carcinomatous component championed by heparin-binding EGF-like growth factor (HB-EGF) predisposing to metastasis and recurrence in stage I uterine malignant mixed mullerian tumor. Hum Pathol. 2016 07; 53:159-67.