T-Lymphoma Invasion and Metastasis-inducing Protein 1
"T-Lymphoma Invasion and Metastasis-inducing Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A Rho guanine nucleotide exchange factor that consists of two pleckstrin homology domains flanking central Ras-binding, Dbl-homology (DH) and PDZ domains. It stimulates GTP-GDP exchange of rho-like GTPases such as RAC1 PROTEIN; CDC42 PROTEIN; and RHOA PROTEIN, and functions to link extracellular signals to remodeling of the CYTOSKELETON for CELL ADHESION and CELL MOVEMENT.
| Descriptor ID |
D000075684
|
| MeSH Number(s) |
D12.644.360.325.300.850 D12.776.476.325.300.850
|
| Concept/Terms |
|
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