"Forkhead Box Protein L2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A forkhead box transcription factor that is expressed in the developing eyelid and during very early development of the gonad, prior to sex determination. It is essential for development of the ovary and inhibits SOX9 TRANSCRIPTION FACTOR to prevent differentiation to testes. It also induces APOPTOSIS in ovarian cells. Mutations in the FOXL2 gene are associated with BLEPHAROPHIMOSIS; Ptosis, and Epicanthus inversus (BPES with ovarian failure).
| Descriptor ID |
D000074842
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| MeSH Number(s) |
D12.776.260.950.249.032 D12.776.930.977.249.032
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Forkhead Box Protein L2".
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Below are the most recent publications written about "Forkhead Box Protein L2" by people in Profiles.