AlkB Homolog 4, Lysine Demethylase
"AlkB Homolog 4, Lysine Demethylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dioxygenase and alkylation repair homolog that mediates demethylation of ACTIN monomethylated at 'Lys-84' (K84me1). Demethylation of actin LYSINE 84 (K84me1) is required for maintaining actin and MYOSIN dynamics to support normal cleavage furrow ingression during CYTOKINESIS and CELL MIGRATION. It may also be involved in transcription regulation.
| Descriptor ID |
D000071501
|
| MeSH Number(s) |
D08.811.682.662.582.138 D08.811.682.690.416.139.937
|
| Concept/Terms |
AlkB Homolog 4, Lysine Demethylase- AlkB Homolog 4, Lysine Demethylase
- Alpha-Ketoglutarate-Dependent Dioxygenase Alkb Homolog 4
- Alpha Ketoglutarate Dependent Dioxygenase Alkb Homolog 4
- Alkylated DNA Repair Protein AlkB Homolog 4
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Below are MeSH descriptors whose meaning is more general than "AlkB Homolog 4, Lysine Demethylase".
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