Chitinase-3-Like Protein 1
"Chitinase-3-Like Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lectin that binds CHITIN, but lacks chitinase activity. It may be involved in tissue remodeling and cellular responses to the environment, including the response of type 2 HELPER T-CELLS to INFLAMMATION and sensitization to ALLERGENS. Mutations in the CHI3L1 gene are associated with ASTHMA.
Descriptor ID |
D000071451
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MeSH Number(s) |
D08.811.277.450.207.500 D12.776.503.070
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Concept/Terms |
Chitinase-3-Like Protein 1- Chitinase-3-Like Protein 1
- Chitinase 3 Like Protein 1
- Cartilage Glycoprotein 39
- Glycoprotein 39, Cartilage
- GP-39 Protein
- GP 39 Protein
- YLK-40 Protein
- YLK 40 Protein
- CHI3L1 Protein
- CGP-39 Protein
- CGP 39 Protein
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Below are MeSH descriptors whose meaning is more general than "Chitinase-3-Like Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Chitinase-3-Like Protein 1".
This graph shows the total number of publications written about "Chitinase-3-Like Protein 1" by people in this website by year, and whether "Chitinase-3-Like Protein 1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chitinase-3-Like Protein 1" by people in Profiles.
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Biomarkers of inflammation and repair in kidney disease progression. J Clin Invest. 2021 02 01; 131(3).
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Circulating serum interleukin-6, serum chitinase-3-like protein-1, and plasma vascular endothelial growth factor are not predictive for remission and radiographic progression in patients with early rheumatoid arthritis: post-hoc explorative and validation studies based on the CIMESTRA and OPERA trials. Scand J Rheumatol. 2018 07; 47(4):259-269.
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Chitinase-3-like 1 protein (CHI3L1) locus influences cerebrospinal fluid levels of YKL-40. BMC Neurol. 2016 Nov 10; 16(1):217.
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High serum levels of YKL-40 in patients with systemic sclerosis are associated with pulmonary involvement. Scand J Rheumatol. 2005 Jul-Aug; 34(4):293-7.