"Sitagliptin Phosphate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pyrazine-derived DIPEPTIDYL-PEPTIDASE IV INHIBITOR and HYPOGLYCEMIC AGENT that increases the levels of the INCRETIN hormones GLUCAGON-LIKE PEPTIDE-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). It is used in the treatment of TYPE 2 DIABETES.
| Descriptor ID |
D000068900
|
| MeSH Number(s) |
D03.383.129.799.725 D03.383.679.875
|
| Concept/Terms |
Sitagliptin Phosphate- Sitagliptin Phosphate
- Phosphate, Sitagliptin
- Sitagliptin Phosphate Monohydrate
- Monohydrate, Sitagliptin Phosphate
- Phosphate Monohydrate, Sitagliptin
- Sitagliptin Monophosphate Monohydrate
- Monohydrate, Sitagliptin Monophosphate
- Monophosphate Monohydrate, Sitagliptin
MK 0431- MK 0431
- 0431, MK
- MK0431
- MK-0431
Sitagliptin- Sitagliptin
- 4-Oxo-4-(3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-amine
|
Below are MeSH descriptors whose meaning is more general than "Sitagliptin Phosphate".
Below are MeSH descriptors whose meaning is more specific than "Sitagliptin Phosphate".
This graph shows the total number of publications written about "Sitagliptin Phosphate" by people in this website by year, and whether "Sitagliptin Phosphate" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sitagliptin Phosphate" by people in Profiles.
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Glycemia Reduction in Type 2 Diabetes - Microvascular and Cardiovascular Outcomes. N Engl J Med. 2022 09 22; 387(12):1075-1088.
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Optimization of Metformin in the GRADE Cohort: Effect on Glycemia and Body Weight. Diabetes Care. 2020 05; 43(5):940-947.
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International variation in characteristics and clinical outcomes of patients with type 2 diabetes and heart failure: Insights from TECOS. Am Heart J. 2019 12; 218:57-65.
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Prospective Postmarketing Surveillance of Acute Myocardial Infarction in New Users of Saxagliptin: A Population-Based Study. Diabetes Care. 2018 01; 41(1):39-48.
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Risk for Hospitalized Heart Failure Among New Users of Saxagliptin, Sitagliptin, and Other Antihyperglycemic Drugs: A Retrospective Cohort Study. Ann Intern Med. 2016 Jun 07; 164(11):705-14.