3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)

"3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

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A ketone oxidoreductase that catalyzes the overall conversion of alpha-keto acids to ACYL-CoA and CO2. The enzyme requires THIAMINE DIPHOSPHATE as a cofactor. Defects in genes that code for subunits of the enzyme are a cause of MAPLE SYRUP URINE DISEASE. The enzyme was formerly classified as EC 1.2.4.3.

Descriptor ID	D042942
MeSH Number(s)	D08.811.682.657.350.760
Concept/Terms	3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide) 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide) 2-Oxoisocaproate Dehydrogenase 2 Oxoisocaproate Dehydrogenase Dehydrogenase, 2-Oxoisocaproate 2-Oxoisovalerate Dehydrogenase (Lipoamide) Branched-Chain Keto Acid Dehydrogenase Branched Chain Keto Acid Dehydrogenase BCKA Decarboxylase Decarboxylase, BCKA Branched Chain Alpha-Keto Acid Decarboxylase Branched Chain Alpha Keto Acid Decarboxylase Branched Chain Ketoacid Dehydrogenase Branched-Chain 2-Oxo Acid Dehydrogenase Branched Chain 2 Oxo Acid Dehydrogenase Branched-Chain Oxo-Acid Dehydrogenase Branched Chain Oxo Acid Dehydrogenase Dehydrogenase, Branched-Chain Oxo-Acid Oxo-Acid Dehydrogenase, Branched-Chain Alpha-Keto Acid Dehydrogenase Acid Dehydrogenase, Alpha-Keto Alpha Keto Acid Dehydrogenase Dehydrogenase, Alpha-Keto Acid

Below are MeSH descriptors whose meaning is more general than "3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Oxidoreductases [D08.811.682]
Oxidoreductases Acting on Aldehyde or Oxo Group Donors [D08.811.682.657]
Ketone Oxidoreductases [D08.811.682.657.350]
3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide) [D08.811.682.657.350.760]

Below are MeSH descriptors whose meaning is related to "3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)".

Below are MeSH descriptors whose meaning is more specific than "3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)".

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