1-Alkyl-2-acetylglycerophosphocholine Esterase
"1-Alkyl-2-acetylglycerophosphocholine Esterase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA.
| Descriptor ID |
D043203
|
| MeSH Number(s) |
D08.811.277.352.100.680.750.937.249
|
| Concept/Terms |
1-Alkyl-2-acetylglycerophosphocholine Esterase- 1-Alkyl-2-acetylglycerophosphocholine Esterase
- 1 Alkyl 2 acetylglycerophosphocholine Esterase
- Esterase, 1-Alkyl-2-acetylglycerophosphocholine
- PAF Acetylhydrolase II
- Acetylhydrolase II, PAF
- Platelet-Activating Factor Hydrolase
- Factor Hydrolase, Platelet-Activating
- Hydrolase, Platelet-Activating Factor
- Platelet Activating Factor Hydrolase
- PAF 2-Acylhydrolase
- PAF 2 Acylhydrolase
- Lipoprotein-Associated Phospholipase A2
- Lipoprotein Associated Phospholipase A2
- Phospholipase A2, Lipoprotein-Associated
- Lp-PLA(2)
- Lp-PLA2
- Lp PLA2
- PAF 2-Acetylhydrolase
- 2-Acetylhydrolase, PAF
- PAF 2 Acetylhydrolase
- PAF Acetylhydrolase
- Acetylhydrolase, PAF
- Lipoprotein-Associated Phospholipase A(2)
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Below are MeSH descriptors whose meaning is more general than "1-Alkyl-2-acetylglycerophosphocholine Esterase".
Below are MeSH descriptors whose meaning is more specific than "1-Alkyl-2-acetylglycerophosphocholine Esterase".
This graph shows the total number of publications written about "1-Alkyl-2-acetylglycerophosphocholine Esterase" by people in this website by year, and whether "1-Alkyl-2-acetylglycerophosphocholine Esterase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "1-Alkyl-2-acetylglycerophosphocholine Esterase" by people in Profiles.
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Racial variation in lipoprotein-associated phospholipase A2 in older adults. BMC Cardiovasc Disord. 2011 Jun 29; 11:38.
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Lipoprotein-associated phospholipase A(2) and future risk of subclinical disease and cardiovascular events in individuals with type 2 diabetes: the Cardiovascular Health Study. Diabetologia. 2011 Feb; 54(2):329-33.
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Lipoprotein-associated phospholipase A2 and cardiovascular risk: state of the evidence and future directions. Arterioscler Thromb Vasc Biol. 2006 Jan; 26(1):5-6.
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Association of lipoprotein-associated phospholipase A2 mass and activity with calcified coronary plaque in young adults: the CARDIA study. Arterioscler Thromb Vasc Biol. 2005 Jan; 25(1):216-21.