"B7-2 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A costimulatory ligand glycoprotein that contains a C2 and V-type IMMUNOGLOBULIN DOMAIN. It is expressed by ANTIGEN-PRESENTING CELLS and binds to CD28 ANTIGEN with high specificity and to CTLA-4 ANTIGEN with low specificity. The interaction of CD86 with CD28 ANTIGEN provides a stimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.
| Descriptor ID |
D051940
|
| MeSH Number(s) |
D12.776.467.150.200 D12.776.543.095.200 D23.050.301.285.200 D23.529.168.200
|
| Concept/Terms |
B7-2 Antigen- B7-2 Antigen
- B7 2 Antigen
- B7-2 Costimulatory Molecule
- Costimulatory Molecule, B7-2
- B70 Costimulatory Molecule
- Costimulatory Molecule, B70
- Early T Cell Costimulatory Molecule 1
- CD86 Antigens
- Antigen, B7-2
- Antigen, B7 2
- Antigens, CD86
- CD86 Antigen
- Antigen, CD86
|
Below are MeSH descriptors whose meaning is more general than "B7-2 Antigen".
Below are MeSH descriptors whose meaning is more specific than "B7-2 Antigen".
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