"Cocaine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
| Descriptor ID |
D003042
|
| MeSH Number(s) |
D02.145.074.722.388 D03.132.889.354 D03.605.084.500.722.388 D03.605.869.388
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cocaine".
Below are MeSH descriptors whose meaning is more specific than "Cocaine".
This graph shows the total number of publications written about "Cocaine" by people in this website by year, and whether "Cocaine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cocaine" by people in Profiles.
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Trends in Self-reported and Biochemically Verified Cocaine and Methamphetamine Use Among Pregnant Individuals in Northern California, 2011-2019. JAMA Netw Open. 2022 12 01; 5(12):e2248055.
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Psychostimulant-related deaths among former inmates. J Addict Med. 2012 Jun; 6(2):97-105.
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Cocaine and coronary calcification in young adults: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am Heart J. 2005 Nov; 150(5):921-6.
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Stroke and cocaine or amphetamine use. Epidemiology. 1998 Nov; 9(6):596-600.
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New-onset bronchospasm or recrudescence of asthma associated with cocaine abuse. Acad Emerg Med. 1997 Jul; 4(7):689-92.
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Lifetime cocaine use and cardiovascular characteristics among young adults: the CARDIA study. Am J Public Health. 1997 Apr; 87(4):629-34.
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Cocaine use and characteristics of young adult users from 1987 to 1992: the CARDIA Study. Coronary Artery Risk Development in Young Adults. Am J Public Health. 1996 Dec; 86(12):1736-41.
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Relationship of maternal substance abuse to subsequent sudden infant death syndrome in offspring. J Pediatr. 1993 Jul; 123(1):120-6.