"Collectins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of C-type lectins that target the carbohydrate structures found on invading pathogens. Binding of collectins to microorganisms results in their agglutination and enhanced clearance. Collectins form trimers that may assemble into larger oligomers. Each collectin polypeptide chain consists of four regions: a relatively short N-terminal region, a collagen-like region, an alpha-helical coiled-coil region, and carbohydrate-binding region.
| Descriptor ID |
D037222
|
| MeSH Number(s) |
D12.776.503.280.249
|
| Concept/Terms |
Collectins- Collectins
- Collagenous Lectins
- Lectins, Collagenous
- Collectin
|
Below are MeSH descriptors whose meaning is more general than "Collectins".
Below are MeSH descriptors whose meaning is more specific than "Collectins".
This graph shows the total number of publications written about "Collectins" by people in this website by year, and whether "Collectins" was a major or minor topic of these publications.
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Below are the most recent publications written about "Collectins" by people in Profiles.
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The influence of mannose binding lectin polymorphisms on disease outcome in early polyarthritis. TIRA Group. J Rheumatol. 2001 May; 28(5):935-42.
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Mannose-binding lectin polymorphisms and susceptibility to infection in systemic lupus erythematosus. Arthritis Rheum. 1999 Oct; 42(10):2145-52.