"Receptor, EphA1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The founding member of the EPH FAMILY RECEPTORS. It was first cloned from an erythropoietin-producing human hepatocellular carcinoma cell line and is highly conserved among many mammalian species. Overproduction of the EphA1 receptor is associated with tumors and tumor cells of epithelial origin. It is also expressed at high levels in LIVER; LUNG; and KIDNEY; which is in contrast to many other members of the Eph receptor that are found primarily in tissues of the nervous system.
| Descriptor ID |
D036082
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.850.050 D12.776.543.750.630.500.050
|
| Concept/Terms |
Receptor, EphA1- Receptor, EphA1
- EPHA1 Receptor Tyrosine Kinase
- Eph Receptor
- EPHA1 Protein
- EphA1 Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptor, EphA1".
Below are MeSH descriptors whose meaning is more specific than "Receptor, EphA1".
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Below are the most recent publications written about "Receptor, EphA1" by people in Profiles.
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Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet. 2011 May; 43(5):436-41.