"Phospholipase C gamma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phosphoinositide phospholipase C subtype that is primarily regulated by PROTEIN-TYROSINE KINASES. It is structurally related to PHOSPHOLIPASE C DELTA with the addition of SRC HOMOLOGY DOMAINS and pleckstrin homology domains located between two halves of the CATALYTIC DOMAIN.
Descriptor ID |
D051966
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MeSH Number(s) |
D08.811.277.352.640.700.700.562.750 D12.644.360.571.750 D12.776.476.556.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Phospholipase C gamma".
Below are MeSH descriptors whose meaning is more specific than "Phospholipase C gamma".
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Below are the most recent publications written about "Phospholipase C gamma" by people in Profiles.
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Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nat Genet. 2017 09; 49(9):1373-1384.