In Situ Nick-End Labeling

"In Situ Nick-End Labeling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

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An in situ method for detecting areas of DNA which are nicked during APOPTOSIS. Terminal deoxynucleotidyl transferase is used to add labeled dUTP, in a template-independent manner, to the 3 prime OH ends of either single- or double-stranded DNA. The terminal deoxynucleotidyl transferase nick end labeling, or TUNEL, assay labels apoptosis on a single-cell level, making it more sensitive than agarose gel electrophoresis for analysis of DNA FRAGMENTATION.

Descriptor ID	D020287
MeSH Number(s)	E05.393.475
Concept/Terms	In Situ Nick-End Labeling In Situ Nick-End Labeling TUNEL Nick-End Labeling, In Situ In Situ Nick End Labelling In Situ Nick End Labeling In Situ Nick End-Labelling In Situ Nick-End Labelling Nick End-Labeling, In Situ Nick End Labeling, In Situ Nick End-Labelling, In Situ Nick End Labelling, In Situ Nick-End Labelling, In Situ In Situ Nick End-Labeling

Below are MeSH descriptors whose meaning is more general than "In Situ Nick-End Labeling".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Genetic Techniques [E05.393]
In Situ Nick-End Labeling [E05.393.475]

Below are MeSH descriptors whose meaning is more specific than "In Situ Nick-End Labeling".

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