"Thymidylate Synthase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme of the transferase class that catalyzes the reaction 5,10-methylenetetrahydrofolate and dUMP to dihydrofolate and dTMP in the synthesis of thymidine triphosphate. (From Dorland, 27th ed) EC 2.1.1.45.
| Descriptor ID |
D013940
|
| MeSH Number(s) |
D08.811.913.555.500.862
|
| Concept/Terms |
Thymidylate Synthase- Thymidylate Synthase
- Synthase, Thymidylate
- Thymidylate Synthetase
- Synthetase, Thymidylate
|
Below are MeSH descriptors whose meaning is more general than "Thymidylate Synthase".
Below are MeSH descriptors whose meaning is more specific than "Thymidylate Synthase".
This graph shows the total number of publications written about "Thymidylate Synthase" by people in this website by year, and whether "Thymidylate Synthase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
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Below are the most recent publications written about "Thymidylate Synthase" by people in Profiles.
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Thymidylate synthase polymorphisms and colon cancer: associations with tumor stage, tumor characteristics and survival. Int J Cancer. 2007 May 15; 120(10):2226-32.
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Polymorphisms in the reduced folate carrier, thymidylate synthase, or methionine synthase and risk of colon cancer. Cancer Epidemiol Biomarkers Prev. 2005 Nov; 14(11 Pt 1):2509-16.