Trimetrexate

"Trimetrexate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

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A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against PNEUMOCYSTIS PNEUMONIA in AIDS patients. Myelosuppression is its dose-limiting toxic effect.

Descriptor ID	D016597
MeSH Number(s)	D03.633.100.786.925
Concept/Terms	Trimetrexate Trimetrexate JB-11 JB-11 JB 11 JB11 Trimetrexate Monohydrate, Monoacetate Trimetrexate Monohydrate, Monoacetate Monohydrate, Monoacetate Trimetrexate NSC-328564 NSC-328564 NSC 328564 NSC328564 Trimetrexate Hydrate Trimetrexate Hydrate Hydrate, Trimetrexate CI-898 CI-898 CI 898 CI898 NSC-249008 NSC-249008 NSC 249008 NSC249008

Below are MeSH descriptors whose meaning is more general than "Trimetrexate".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Quinazolines [D03.633.100.786]
Trimetrexate [D03.633.100.786.925]

Below are MeSH descriptors whose meaning is related to "Trimetrexate".

Below are MeSH descriptors whose meaning is more specific than "Trimetrexate".

publications

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