A heterotrimeric GTP-binding protein that mediates the light activation signal from photolyzed rhodopsin to cyclic GMP phosphodiesterase and is pivotal in the visual excitation process. Activation of rhodopsin on the outer membrane of rod and cone cells causes GTP to bind to transducin followed by dissociation of the alpha subunit-GTP complex from the beta/gamma subunits of transducin. The alpha subunit-GTP complex activates the cyclic GMP phosphodiesterase which catalyzes the hydrolysis of cyclic GMP to 5'-GMP. This leads to closure of the sodium and calcium channels and therefore hyperpolarization of the rod cells.

Descriptor ID	D015293
MeSH Number(s)	D08.811.277.040.330.300.200.800 D12.644.360.360.940 D12.776.157.325.332.940 D12.776.476.375.940 D12.776.543.325.800
Concept/Terms	Transducin Transducin Transducin G-Protein (Gt) Gt, Transducin G-Protein G-Protein Gt, Transducin Gt, Transducin G Protein Transducin G-Protein Gt G-Protein, Inhibitory Gt G Protein, Inhibitory Gt Gt G-Protein, Inhibitory Inhibitory Gt G-Protein gamma-Transducin gamma-Transducin gamma Transducin Transducin, gamma Subunit gamma Subunit Transducin beta-Transducin beta-Transducin beta Transducin Transducin, beta Subunit beta Subunit Transducin alpha-Transducin alpha-Transducin alpha Transducin Transducin, alpha Subunit alpha Subunit Transducin

Below are MeSH descriptors whose meaning is more general than "Transducin".

Below are MeSH descriptors whose meaning is related to "Transducin".

Below are MeSH descriptors whose meaning is more specific than "Transducin".