Valosin Containing Protein
"Valosin Containing Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly-conserved AAA ATPase that functions in the biogenesis of the transitional ENDOPLASMIC RETICULUM and fragmentation and reassembly of the GOLGI APPARATUS during MITOSIS. It also functions in a complex with UFD1L and NPLOC4 proteins to export misfolded ubiquitinated proteins from the endoplasmic reticulum and outer mitochondrial membrane to the cytoplasm for degradation by the PROTEASOME and also plays a role in AUTOPHAGY of ubiquitinated proteins. It occurs in neuronal INCLUSION BODIES from patients with AMYOTROPHIC LATERAL SCLEROSIS and LEWY BODIES from PARKINSON DISEASE patients.
| Descriptor ID |
D000074405
|
| MeSH Number(s) |
D08.811.277.040.013.500.750 D08.811.277.040.025.024.750 D12.776.157.025.750.750 D12.776.167.800
|
| Concept/Terms |
Valosin Containing Protein- Valosin Containing Protein
- Cell Cycle Protein CDC48
- Valosine-Containing Protein
- Valosine Containing Protein
- p97 Valosin-Containing Protein
- Valosin-Containing Protein, p97
- p97 Valosin Containing Protein
- Valosin-Containing Protein
- CDC48 Protein
- Cell Cycle Protein CDC48p
|
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