"Complement C5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
C5 plays a central role in both the classical and the alternative pathway of COMPLEMENT ACTIVATION. C5 is cleaved by C5 CONVERTASE into COMPLEMENT C5A and COMPLEMENT C5B. The smaller fragment C5a is an ANAPHYLATOXIN and mediator of inflammatory process. The major fragment C5b binds to the membrane initiating the spontaneous assembly of the late complement components, C5-C9, into the MEMBRANE ATTACK COMPLEX.
| Descriptor ID |
D003182
|
| MeSH Number(s) |
D12.776.124.486.274.450
|
| Concept/Terms |
Complement C5- Complement C5
- C5, Complement
- C5 Complement
- Complement, C5
- Complement 5
- Complement Component 5
- Component 5, Complement
Complement C5, Precursor- Complement C5, Precursor
- C5, Precursor Complement
- Precursor Complement C5
- Pro-C5
- Pro C5
- Pro-complement 5
- Pro complement 5
- Precursor C5
- C5, Precursor
|
Below are MeSH descriptors whose meaning is more general than "Complement C5".
Below are MeSH descriptors whose meaning is more specific than "Complement C5".
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