"Leptin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.
| Descriptor ID |
D020738
|
| MeSH Number(s) |
D06.472.699.042.500 D12.644.276.024.500 D12.644.548.011.500 D12.776.467.024.500 D23.529.024.500
|
| Concept/Terms |
Leptin- Leptin
- Obese Protein
- Obese Gene Product
- Gene Product, Obese
- Ob Gene Product
- Gene Product, Ob
- Ob Protein
|
Below are MeSH descriptors whose meaning is more general than "Leptin".
Below are MeSH descriptors whose meaning is more specific than "Leptin".
This graph shows the total number of publications written about "Leptin" by people in this website by year, and whether "Leptin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 2 | 0 | 2 |
| 2004 | 0 | 1 | 1 |
| 2006 | 2 | 3 | 5 |
| 2007 | 2 | 2 | 4 |
| 2008 | 3 | 0 | 3 |
| 2009 | 1 | 1 | 2 |
| 2011 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "Leptin" by people in Profiles.
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Genetic variation in the SIM1 locus is associated with erectile dysfunction. Proc Natl Acad Sci U S A. 2018 10 23; 115(43):11018-11023.
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Longitudinal Increases in Adiposity Contribute to Worsening Adipokine Profile over Time in Mexican Americans. Obesity (Silver Spring). 2018 04; 26(4):703-712.
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Ghrelin and Leptin Have a Complex Relationship with Risk of Barrett's Esophagus. Dig Dis Sci. 2016 Jan; 61(1):70-9.
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Lactation intensity and fasting plasma lipids, lipoproteins, non-esterified free fatty acids, leptin and adiponectin in postpartum women with recent gestational diabetes mellitus: the SWIFT cohort. Metabolism. 2014 Jul; 63(7):941-50.
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Obesity-related hormones and endometrial cancer among postmenopausal women: a nested case-control study within the B~FIT cohort. Endocr Relat Cancer. 2013 Feb; 20(1):151-60.
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Metabolic and inflammatory links to depression in youth with diabetes. Diabetes Care. 2012 Dec; 35(12):2443-6.
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Central obesity, leptin and cognitive decline: the Sacramento Area Latino Study on Aging. Dement Geriatr Cogn Disord. 2012; 33(6):400-9.
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A low-glycemic load diet reduces serum C-reactive protein and modestly increases adiponectin in overweight and obese adults. J Nutr. 2012 Feb; 142(2):369-74.
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Duration of lactation and maternal adipokines at 3 years postpartum. Diabetes. 2011 Apr; 60(4):1277-85.
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Late-life dementias: does this unyielding global challenge require a broader view? JAMA. 2009 Dec 16; 302(23):2593-4.