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Jennifer Bobb, PhD

TitleAssistant Investigator
InstitutionKaiser Permanente Washington
DepartmentHealth Research Institute
ORCID ORCID Icon0000-0002-4744-5897 Additional info
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    Collapse Overview 
    Collapse overview
    Jennifer Bobb, PhD, aims to apply rigorous statistical methods to address important problems in public health. She is interested in statistical issues that occur when data that were not originally collected for research purposes, such as administrative claims data or electronic health records, are used for addressing scientific questions of relevance to clinical practice and health policy.

    At KPWHRI, Dr. Bobb collaborates with scientists across a broad range of research areas, including studies of aging and cognitive function, women’s health, and behavioral health. As an investigator with the Addictions Research Network, she provides statistical leadership on pragmatic clinical trials at Kaiser Permanente Washington and other health systems. She is the lead statistician on a study to evaluate whether exposure to prescription opioids during early pregnancy increases the risk of neural tube defects, as part of the Medication Exposure in Pregnancy Risk Evaluation Program funded by the Food and Drug Administration (FDA), as well as on the Adult Changes in Thought (ACT) study, a cohort study investigating the factors that contribute to dementia, Alzheimer’s disease, and healthy aging.

    Dr. Bobb also has expertise in environmental biostatistics, where she has led large-scale epidemiological investigations on the health effects of exposure to extreme heat and air pollution and worked with interdisciplinary teams to study the health impact of changing environmental stressors under global climate change. She also developed flexible modeling approaches for estimating the health effects of multi-pollutant mixtures that broadly apply to settings where a large number of exposures may interact or have complex relationships with health, along with publicly available software implementing these methods.

    Dr. Bobb is an affiliate assistant professor in biostatistics at the University of Washington. She is also an associate editor of the journal Biostatistics. She serves on the Regional Advisory Board of the Western North American Region of the International Biometric Society and is a member of the American Statistical Association. Before joining KPWHRI, Dr. Bobb completed her PhD in biostatistics at the Johns Hopkins Bloomberg School of Public Health in 2012, followed by a postdoctoral fellowship at the Harvard T.H. Chan School of Public Health.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Williams EC, McGinnis KA, Tate JP, Matson TE, Rubinsky AD, Bobb JF, Lapham GT, Edelman EJ, Catz SL, Satre DD, Bryant KJ, Marshall BDL, Kraemer KL, Bensley KM, Richards JE, Skanderson M, Justice AC, Fiellin DA, Bradley KA. HIV Disease Severity is Sensitive to Temporal Changes in Alcohol Use: A National Study of VA Patients with HIV. J Acquir Immune Defic Syndr. 2019 Apr 15. PMID: 30973541.
      View in: PubMed
    2. Shortreed SM, Cook AJ, Coley RY, Bobb JF, Nelson JC. Challenges and Opportunities for Using Big Health Care Data to Advance Medical Science and Public Health. Am J Epidemiol. 2019 Mar 16. PMID: 30877288.
      View in: PubMed
    3. Drewnowski A, Arterburn D, Zane J, Aggarwal A, Gupta S, Hurvitz PM, Moudon AV, Bobb J, Cook A, Lozano P, Rosenberg D. The Moving to Health (M2H) approach to natural experiment research: A paradigm shift for studies on built environment and health. SSM Popul Health. 2019 Apr; 7:100345. PMID: 30656207.
      View in: PubMed
    4. Liu SH, Bobb JF, Claus Henn B, Gennings C, Schnaas L, Tellez-Rojo M, Bellinger D, Arora M, Wright RO, Coull BA. Bayesian varying coefficient kernel machine regression to assess neurodevelopmental trajectories associated with exposure to complex mixtures. Stat Med. 2018 Dec 30; 37(30):4680-4694. PMID: 30277584.
      View in: PubMed
    5. Bobb JF, Claus Henn B, Valeri L, Coull BA. Statistical software for analyzing the health effects of multiple concurrent exposures via Bayesian kernel machine regression. Environ Health. 2018 08 20; 17(1):67. PMID: 30126431.
      View in: PubMed
    6. Glass JE, Bobb JF, Lee AK, Richards JE, Lapham GT, Ludman E, Achtmeyer C, Caldeiro RM, Parrish R, Williams EC, Lozano P, Bradley KA. Study protocol: a cluster-randomized trial implementing Sustained Patient-centered Alcohol-related Care (SPARC trial). Implement Sci. 2018 08 06; 13(1):108. PMID: 30081930.
      View in: PubMed
    7. Sordillo JE, Switkowski KM, Coull BA, Schwartz J, Kloog I, Gibson H, Litonjua AA, Bobb J, Koutrakis P, Rifas-Shiman SL, Oken E, Gold DR. Relation of Prenatal Air Pollutant and Nutritional Exposures with Biomarkers of Allergic Disease in Adolescence. Sci Rep. 2018 Jul 12; 8(1):10578. PMID: 30002468.
      View in: PubMed
    8. Liu SH, Bobb JF, Lee KH, Gennings C, Claus Henn B, Bellinger D, Austin C, Schnaas L, Tellez-Rojo MM, Hu H, Wright RO, Arora M, Coull BA. Lagged kernel machine regression for identifying time windows of susceptibility to exposures of complex mixtures. Biostatistics. 2018 07 01; 19(3):325-341. PMID: 28968676.
      View in: PubMed
    9. Yitshak-Sade M, Bobb JF, Schwartz JD, Kloog I, Zanobetti A. The association between short and long-term exposure to PM2.5 and temperature and hospital admissions in New England and the synergistic effect of the short-term exposures. Sci Total Environ. 2018 Oct 15; 639:868-875. PMID: 29929325.
      View in: PubMed
    10. Williams EC, McGinnis KA, Bobb JF, Rubinsky AD, Lapham GT, Skanderson M, Catz SL, Bensley KM, Richards JE, Bryant KJ, Edelman EJ, Satre DD, Marshall BDL, Kraemer KL, Blosnich JR, Crystal S, Gordon AJ, Fiellin DA, Justice AC, Bradley KA. Changes in alcohol use associated with changes in HIV disease severity over time: A national longitudinal study in the Veterans Aging Cohort. Drug Alcohol Depend. 2018 08 01; 189:21-29. PMID: 29859388.
      View in: PubMed
    11. Liu SH, Bobb JF, Henn BC, Schnaas L, Tellez-Rojo MM, Gennings C, Arora M, Wright RO, Coull BA, Wand MP. Modeling the health effects of time-varying complex environmental mixtures: Mean field variational Bayes for lagged kernel machine regression. Environmetrics. 2018 Jun; 29(4). PMID: 30686915.
      View in: PubMed
    12. Bradley KA, Bobb JF, Ludman EJ, Chavez LJ, Saxon AJ, Merrill JO, Williams EC, Hawkins EJ, Caldeiro RM, Achtmeyer CE, Greenberg DM, Lapham GT, Richards JE, Lee AK, Kivlahan DR. Alcohol-Related Nurse Care Management in Primary Care: A Randomized Clinical Trial. JAMA Intern Med. 2018 05 01; 178(5):613-621. PMID: 29582088.
      View in: PubMed
    13. Hopp S, Dominici F, Bobb JF. Medical diagnoses of heat wave-related hospital admissions in older adults. Prev Med. 2018 05; 110:81-85. PMID: 29428173.
      View in: PubMed
    14. Bobb JF, Lee AK, Lapham GT, Oliver M, Ludman E, Achtmeyer C, Parrish R, Caldeiro RM, Lozano P, Richards JE, Bradley KA. Evaluation of a Pilot Implementation to Integrate Alcohol-Related Care within Primary Care. Int J Environ Res Public Health. 2017 09 08; 14(9). PMID: 28885557.
      View in: PubMed
    15. Valeri L, Mazumdar MM, Bobb JF, Claus Henn B, Rodrigues E, Sharif OIA, Kile ML, Quamruzzaman Q, Afroz S, Golam M, Amarasiriwardena C, Bellinger DC, Christiani DC, Coull BA, Wright RO. The Joint Effect of Prenatal Exposure to Metal Mixtures on Neurodevelopmental Outcomes at 20-40 Months of Age: Evidence from Rural Bangladesh. Environ Health Perspect. 2017 06 26; 125(6):067015. PMID: 28669934.
      View in: PubMed
    16. Bradley KA, Ludman EJ, Chavez LJ, Bobb JF, Ruedebusch SJ, Achtmeyer CE, Merrill JO, Saxon AJ, Caldeiro RM, Greenberg DM, Lee AK, Richards JE, Thomas RM, Matson TE, Williams EC, Hawkins E, Lapham G, Kivlahan DR. Patient-centered primary care for adults at high risk for AUDs: the Choosing Healthier Drinking Options In primary CarE (CHOICE) trial. Addict Sci Clin Pract. 2017 05 17; 12(1):15. PMID: 28514963.
      View in: PubMed
    17. Williams EC, Lapham GT, Bobb JF, Rubinsky AD, Catz SL, Shortreed SM, Bensley KM, Bradley KA. Documented brief intervention not associated with resolution of unhealthy alcohol use one year later among VA patients living with HIV. J Subst Abuse Treat. 2017 07; 78:8-14. PMID: 28554608.
      View in: PubMed
    18. Williams EC, Lapham GT, Shortreed SM, Rubinsky AD, Bobb JF, Bensley KM, Catz SL, Richards JE, Bradley KA. Among patients with unhealthy alcohol use, those with HIV are less likely than those without to receive evidence-based alcohol-related care: A national VA study. Drug Alcohol Depend. 2017 05 01; 174:113-120. PMID: 28324813.
      View in: PubMed
    19. Bobb JF, Ho KK, Yeh RW, Harrington L, Zai A, Liao KP, Dominici F. Time-Course of Cause-Specific Hospital Admissions During Snowstorms: An Analysis of Electronic Medical Records From Major Hospitals in Boston, Massachusetts. Am J Epidemiol. 2017 02 15; 185(4):283-294. PMID: 28137774.
      View in: PubMed
    20. Valeri L, Patterson-Lomba O, Gurmu Y, Ablorh A, Bobb J, Townes FW, Harling G. Predicting Subnational Ebola Virus Disease Epidemic Dynamics from Sociodemographic Indicators. PLoS One. 2016; 11(10):e0163544. PMID: 27732614.
      View in: PubMed
    21. Wang Y, Bobb JF, Papi B, Wang Y, Kosheleva A, Di Q, Schwartz JD, Dominici F. Heat stroke admissions during heat waves in 1,916 US counties for the period from 1999 to 2010 and their effect modifiers. Environ Health. 2016 08 08; 15(1):83. PMID: 27503399.
      View in: PubMed
    22. Johnson S, Bobb JF, Ito K, Savitz DA, Elston B, Shmool JL, Dominici F, Ross Z, Clougherty JE, Matte T. Ambient Fine Particulate Matter, Nitrogen Dioxide, and Preterm Birth in New York City. Environ Health Perspect. 2016 08; 124(8):1283-90. PMID: 26862865.
      View in: PubMed
    23. Shmool JL, Bobb JF, Ito K, Elston B, Savitz DA, Ross Z, Matte TD, Johnson S, Dominici F, Clougherty JE. Area-level socioeconomic deprivation, nitrogen dioxide exposure, and term birth weight in New York City. Environ Res. 2015 Oct; 142:624-32. PMID: 26318257.
      View in: PubMed
    24. Savitz DA, Elston B, Bobb JF, Clougherty JE, Dominici F, Ito K, Johnson S, McAlexander T, Ross Z, Shmool JL, Matte TD, Wellenius GA. Ambient Fine Particulate Matter, Nitrogen Dioxide, and Hypertensive Disorders of Pregnancy in New York City. Epidemiology. 2015 Sep; 26(5):748-57. PMID: 26237745.
      View in: PubMed
    25. Coull BA, Bobb JF, Wellenius GA, Kioumourtzoglou MA, Mittleman MA, Koutrakis P, Godleski JJ. Part 1. Statistical Learning Methods for the Effects of Multiple Air Pollution Constituents. Res Rep Health Eff Inst. 2015 Jun; (183 Pt 1-2):5-50. PMID: 26333238.
      View in: PubMed
    26. Bobb JF, Valeri L, Claus Henn B, Christiani DC, Wright RO, Mazumdar M, Godleski JJ, Coull BA. Bayesian kernel machine regression for estimating the health effects of multi-pollutant mixtures. Biostatistics. 2015 Jul; 16(3):493-508. PMID: 25532525.
      View in: PubMed
    27. Bobb JF, Obermeyer Z, Wang Y, Dominici F. Cause-specific risk of hospital admission related to extreme heat in older adults. JAMA. 2014 Dec 24-31; 312(24):2659-67. PMID: 25536257.
      View in: PubMed
    28. Bobb JF, Peng RD, Bell ML, Dominici F. Heat-related mortality and adaptation to heat in the United States. Environ Health Perspect. 2014 Aug; 122(8):811-6. PMID: 24780880.
      View in: PubMed
    29. Savitz DA, Bobb JF, Carr JL, Clougherty JE, Dominici F, Elston B, Ito K, Ross Z, Yee M, Matte TD. Ambient fine particulate matter, nitrogen dioxide, and term birth weight in New York, New York. Am J Epidemiol. 2014 Feb 15; 179(4):457-66. PMID: 24218031.
      View in: PubMed
    30. Roberts AL, Lyall K, Hart JE, Laden F, Just AC, Bobb JF, Koenen KC, Ascherio A, Weisskopf MG. Perinatal air pollutant exposures and autism spectrum disorder in the children of Nurses' Health Study II participants. Environ Health Perspect. 2013 Aug; 121(8):978-84. PMID: 23816781.
      View in: PubMed
    31. Bobb JF, Dominici F, Peng RD. Reduced hierarchical models with application to estimating health effects of simultaneous exposure to multiple pollutants. J R Stat Soc Ser C Appl Stat. 2013 May; 62(3). PMID: 24357883.
      View in: PubMed
    32. Bobb JF, Schwartz BS, Davatzikos C, Caffo B. Cross-sectional and longitudinal association of body mass index and brain volume. Hum Brain Mapp. 2014 Jan; 35(1):75-88. PMID: 23008165.
      View in: PubMed
    33. Bobb JF, Dominici F, Peng RD. A Bayesian model averaging approach for estimating the relative risk of mortality associated with heat waves in 105 U.S. cities. Biometrics. 2011 Dec; 67(4):1605-16. PMID: 21447046.
      View in: PubMed
    34. Peng RD, Bobb JF, Tebaldi C, McDaniel L, Bell ML, Dominici F. Toward a quantitative estimate of future heat wave mortality under global climate change. Environ Health Perspect. 2011 May; 119(5):701-6. PMID: 21193384.
      View in: PubMed
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    KP Researcher Profiles is funded by Kaiser Permanente Research.